KEGG   PATHWAY: thai00230
Entry
thai00230                   Pathway                                
Name
Purine metabolism - Thalassospira sp. A40-3
Class
Metabolism; Nucleotide metabolism
Pathway map
thai00230  Purine metabolism
thai00230

Module
thai_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:thai00230]
thai_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:thai00230]
thai_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:thai00230]
thai_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:thai00230]
thai_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:thai00230]
thai_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:thai00230]
Other DBs
GO: 0006163 0042278
Organism
Thalassospira sp. A40-3 [GN:thai]
Gene
IT893_10010  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
IT893_08895  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
IT893_15455  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
IT893_05985  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
IT893_03150  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
IT893_11860  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
IT893_13950  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
IT893_13940  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
IT893_13945  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
IT893_11855  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
IT893_13605  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
IT893_13600  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
IT893_13935  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
IT893_13895  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
IT893_18325  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
IT893_10255  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
IT893_09435  5'-nucleotidase C-terminal domain-containing protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
IT893_09070  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
IT893_09405  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
IT893_15465  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
IT893_07170  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
IT893_12725  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
IT893_11885  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
IT893_18910  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
IT893_00670  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
IT893_17625  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
IT893_17620  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
IT893_15435  GMP synthase [KO:K01951] [EC:6.3.5.2]
IT893_12710  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
IT893_17610  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
IT893_06075  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
IT893_10715  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
IT893_02925  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
IT893_03410  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
IT893_08150  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
IT893_11750  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
IT893_12740  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
IT893_05710  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IT893_00470  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IT893_03370  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IT893_09975  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IT893_13525  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IT893_15345  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IT893_19470  hypothetical protein [KO:K01768] [EC:4.6.1.1]
IT893_20005  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IT893_09840  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
IT893_06690  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
IT893_03060  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
IT893_19475  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
IT893_16060  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
IT893_11230  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
IT893_12185  adenylate kinase [KO:K00939] [EC:2.7.4.3]
IT893_08510  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
IT893_10795  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
IT893_14320  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
IT893_05610  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
IT893_05615  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
IT893_17630  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
IT893_18545  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
IT893_17635  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
IT893_17645  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
IT893_05170  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
IT893_17650  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
IT893_17505  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
IT893_17510  urease subunit beta [KO:K01429] [EC:3.5.1.5]
IT893_17515  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
IT893_07025  gamma-glutamyltransferase family protein [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
thai00030  Pentose phosphate pathway
thai00220  Arginine biosynthesis
thai00250  Alanine, aspartate and glutamate metabolism
thai00260  Glycine, serine and threonine metabolism
thai00340  Histidine metabolism
thai00630  Glyoxylate and dicarboxylate metabolism
thai00730  Thiamine metabolism
thai00740  Riboflavin metabolism
thai00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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