KEGG   PATHWAY: ume00630
Entry
ume00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Umezawaea sp. Da 62-37
Class
Metabolism; Carbohydrate metabolism
Pathway map
ume00630  Glyoxylate and dicarboxylate metabolism
ume00630

Module
ume_M00621  Glycine cleavage system [PATH:ume00630]
Other DBs
GO: 0046487 0043648
Organism
Umezawaea sp. Da 62-37 [GN:ume]
Gene
RM788_26690  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
RM788_16920  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
RM788_21490  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
RM788_28055  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
RM788_28175  citrate synthase [KO:K01647] [EC:2.3.3.1]
RM788_48945  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
RM788_10760  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
RM788_15295  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RM788_17970  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RM788_24440  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RM788_29440  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RM788_50445  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RM788_17975  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
RM788_18105  protein meaA [KO:K14447] [EC:5.4.99.63]
RM788_20980  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
RM788_20940  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
RM788_21070  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
RM788_21075  methylmalonyl-CoA mutase family protein [KO:K01847] [EC:5.4.99.2]
RM788_45780  methylaspartate mutase [KO:K19268] [EC:5.4.99.1]
RM788_38905  cobalamin-dependent protein [KO:K01846] [EC:5.4.99.1]
RM788_45775  cobalamin B12-binding domain-containing protein [KO:K01846] [EC:5.4.99.1]
RM788_08485  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
RM788_24185  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
RM788_05995  catalase [KO:K03781] [EC:1.11.1.6]
RM788_26470  catalase [KO:K03781] [EC:1.11.1.6]
RM788_48750  catalase [KO:K03781] [EC:1.11.1.6]
RM788_50275  catalase [KO:K03781] [EC:1.11.1.6]
RM788_06205  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
RM788_27870  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
RM788_51350  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
RM788_01875  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RM788_07205  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RM788_11160  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RM788_30650  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RM788_30730  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
RM788_15255  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RM788_42140  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RM788_13800  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
RM788_47230  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
RM788_47225  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
RM788_15260  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
RM788_18255  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
RM788_35825  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
RM788_13830  gcvH; glycine cleavage system protein GcvH [KO:K02437]
RM788_20185  gcvH; glycine cleavage system protein GcvH [KO:K02437]
RM788_16885  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
RM788_16895  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
RM788_16890  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
RM788_16880  glycerate kinase [KO:K00865] [EC:2.7.1.165]
RM788_35880  glycerate kinase [KO:K00865] [EC:2.7.1.165]
RM788_49875  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RM788_19705  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RM788_36260  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RM788_20230  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
RM788_23210  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ume00010  Glycolysis / Gluconeogenesis
ume00020  Citrate cycle (TCA cycle)
ume00030  Pentose phosphate pathway
ume00053  Ascorbate and aldarate metabolism
ume00071  Fatty acid degradation
ume00230  Purine metabolism
ume00250  Alanine, aspartate and glutamate metabolism
ume00260  Glycine, serine and threonine metabolism
ume00620  Pyruvate metabolism
ume00710  Carbon fixation by Calvin cycle
ume00750  Vitamin B6 metabolism
ume00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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