KEGG   PATHWAY: zju00053
Entry
zju00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Ziziphus jujuba (Chinese jujube)
Class
Metabolism; Carbohydrate metabolism
Pathway map
zju00053  Ascorbate and aldarate metabolism
zju00053

Module
zju_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:zju00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Ziziphus jujuba (Chinese jujube) [GN:zju]
Gene
107407569  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
107415933  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
107428892  UDP-glucose 6-dehydrogenase 5 [KO:K00012] [EC:1.1.1.22]
107421126  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
107415267  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
107432793  inositol oxygenase 4 [KO:K00469] [EC:1.13.99.1]
107424630  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
107432774  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
107429605  inositol oxygenase 1 [KO:K00469] [EC:1.13.99.1]
107430805  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
107430806  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
107430804  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
107429630  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
107431284  aldose reductase isoform X1 [KO:K00002] [EC:1.1.1.2]
107420638  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
107404356  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
125423703  probable L-gulonolactone oxidase 6 isoform X2 [KO:K00103] [EC:1.1.3.8]
107403832  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
107423798  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
107423797  probable L-gulonolactone oxidase 4 [KO:K00103] [EC:1.1.3.8]
107423858  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
107423856  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
107412204  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
107413123  GDP-mannose 3,5-epimerase 1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
107416252  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
107432716  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
107435207  inositol-phosphate phosphatase [KO:K10047] [EC:3.1.3.25 3.1.3.93]
107426610  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
107427462  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
107433785  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
107423612  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
107422361  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
107419385  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
107414699  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
107420538  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
132800370  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
132799157  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
125421739  monodehydroascorbate reductase, seedling isozyme [KO:K08232] [EC:1.6.5.4]
107430170  monodehydroascorbate reductase, chloroplastic/mitochondrial isoform X1 [KO:K08232] [EC:1.6.5.4]
107434950  monodehydroascorbate reductase, seedling isozyme [KO:K08232] [EC:1.6.5.4]
107429997  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
107415283  monodehydroascorbate reductase 4, peroxisomal [KO:K08232] [EC:1.6.5.4]
107434770  monodehydroascorbate reductase, seedling isozyme [KO:K08232] [EC:1.6.5.4]
107404477  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
107405610  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
132803817  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
107411283  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
107424422  L-ascorbate peroxidase 3-like isoform X1 [KO:K00434] [EC:1.11.1.11]
107432898  L-ascorbate peroxidase 2, cytosolic isoform X1 [KO:K00434] [EC:1.11.1.11]
107421180  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
107413560  glutathione S-transferase DHAR1, mitochondrial isoform X1 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
107416296  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
107410428  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
107419354  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107419355  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107405734  aldehyde dehydrogenase family 2 member B4, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
132803832  aldehyde dehydrogenase family 3 member H1 isoform X1 [KO:K00128] [EC:1.2.1.3]
107425367  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
125421093  aldehyde dehydrogenase family 3 member F1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
107412581  aldehyde dehydrogenase family 3 member F1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
107428629  aldehyde dehydrogenase family 2 member B7, mitochondrial [KO:K00128] [EC:1.2.1.3]
107423905  aldehyde dehydrogenase family 7 member A1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
zju00020  Citrate cycle (TCA cycle)
zju00040  Pentose and glucuronate interconversions
zju00051  Fructose and mannose metabolism
zju00520  Amino sugar and nucleotide sugar metabolism
zju00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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