KEGG   PATHWAY: pauu00230
Entry
pauu00230                   Pathway                                
Name
Purine metabolism - Polyangium aurulentum
Class
Metabolism; Nucleotide metabolism
Pathway map
pauu00230  Purine metabolism
pauu00230

Module
pauu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pauu00230]
pauu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pauu00230]
pauu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pauu00230]
pauu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pauu00230]
Other DBs
GO: 0006163 0042278
Organism
Polyangium aurulentum [GN:pauu]
Gene
E8A73_011730  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
E8A73_003595  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
E8A73_048220  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
E8A73_047105  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
E8A73_014770  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
E8A73_012365  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
E8A73_002210  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
E8A73_025755  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
E8A73_018600  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
E8A73_007025  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
E8A73_022585  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
E8A73_022590  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
E8A73_025750  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
E8A73_011320  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
E8A73_030715  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
E8A73_047970  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
E8A73_012070  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
E8A73_023925  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
E8A73_047965  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
E8A73_047460  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
E8A73_017610  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
E8A73_013670  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
E8A73_016930  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
E8A73_047990  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
E8A73_011175  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
E8A73_046960  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K00087] [EC:1.17.1.4]
E8A73_046965  FAD binding domain-containing protein [KO:K11178] [EC:1.17.1.4]
E8A73_046955  (2Fe-2S)-binding protein [KO:K13483]
E8A73_023670  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
E8A73_033950  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
E8A73_032310  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
E8A73_005175  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
E8A73_025825  guanine deaminase [KO:K01487] [EC:3.5.4.3]
E8A73_035275  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
E8A73_019290  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
E8A73_013470  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
E8A73_032615  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
E8A73_017300  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
E8A73_024425  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
E8A73_010940  FHA domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8A73_014780  FHA domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8A73_017890  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8A73_022235  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8A73_030805  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8A73_046600  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8A73_048060  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8A73_015025  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
E8A73_016975  deoxynucleoside kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
E8A73_006975  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
E8A73_037060  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
E8A73_013990  adenylate kinase [KO:K00939] [EC:2.7.4.3]
E8A73_030480  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
E8A73_003655  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
E8A73_016795  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
E8A73_019685  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
E8A73_016790  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
E8A73_024130  cysC; adenylyl-sulfate kinase [KO:K00958] [EC:2.7.7.4]
E8A73_001100  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
E8A73_001095  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
E8A73_001085  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
E8A73_001090  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pauu00030  Pentose phosphate pathway
pauu00220  Arginine biosynthesis
pauu00250  Alanine, aspartate and glutamate metabolism
pauu00260  Glycine, serine and threonine metabolism
pauu00340  Histidine metabolism
pauu00630  Glyoxylate and dicarboxylate metabolism
pauu00730  Thiamine metabolism
pauu00740  Riboflavin metabolism
pauu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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