KEGG   PATHWAY: pfa00230
Entry
pfa00230                    Pathway                                
Name
Purine metabolism - Plasmodium falciparum 3D7
Class
Metabolism; Nucleotide metabolism
Pathway map
pfa00230  Purine metabolism
pfa00230

Module
pfa_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pfa00230]
pfa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pfa00230]
pfa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pfa00230]
pfa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pfa00230]
Other DBs
GO: 0006163 0042278
Organism
Plasmodium falciparum 3D7 [GN:pfa]
Gene
PF3D7_1012500  phosphoglucomutase, putative [KO:K01835] [EC:5.4.2.2]
PF3D7_1325100  phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
PF3D7_1327800  ribose-phosphate pyrophosphokinase, putative [KO:K00948] [EC:2.7.6.1]
PF3D7_0206700  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
PF3D7_1206100  IMP-specific 5'-nucleotidase, putative [KO:K18550] [EC:3.1.3.99 3.1.3.-]
PF3D7_1012400  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
PF3D7_0920800  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
PF3D7_1366500  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
PF3D7_0605600  nucleoside diphosphate kinase, putative [KO:K00940] [EC:2.7.4.6]
PF3D7_0720800  Ham1-like protein, putative [KO:K01519] [EC:3.6.1.66]
PF3D7_0520600  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
PF3D7_1012600  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
PF3D7_0928900  guanylate kinase [KO:K00942] [EC:2.7.4.8]
PF3D7_1437200  ribonucleoside-diphosphate reductase large subunit, putative [KO:K10807] [EC:1.17.4.1]
PF3D7_1015800  ribonucleoside-diphosphate reductase small chain, putative [KO:K10808] [EC:1.17.4.1]
PF3D7_1405600  ribonucleoside-diphosphate reductase small chain, putative [KO:K10808] [EC:1.17.4.1]
PF3D7_1402000  conserved Plasmodium protein, unknown function [KO:K01514] [EC:3.6.1.11]
PF3D7_1360500  guanylyl cyclase beta [KO:K01769] [EC:4.6.1.2]
PF3D7_1470500  cGMP-specific 3',5'-cyclic phosphodiesterase delta [KO:K01120] [EC:3.1.4.17]
PF3D7_1209500.1  cGMP-specific 3',5'-cyclic phosphodiesterase alpha [KO:K01120] [EC:3.1.4.17]
PF3D7_1321500.1  3',5'-cyclic nucleotide phosphodiesterase beta [KO:K01120] [EC:3.1.4.17]
PF3D7_1354500  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
PF3D7_1329400  AMP deaminase [KO:K01490] [EC:3.5.4.6]
PF3D7_1029600  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
PF3D7_1008900  adenylate kinase [KO:K00939] [EC:2.7.4.3]
PF3D7_0415600  GTP:AMP phosphotransferase [KO:K00939] [EC:2.7.4.3]
PF3D7_0816900  adenylate kinase 2 [KO:K00939] [EC:2.7.4.3]
PF3D7_0110900  adenylate kinase-like protein 1 [KO:K18532] [EC:2.7.4.3]
PF3D7_1321600  cGMP-specific 3',5'-cyclic phosphodiesterase gamma, putative [KO:K13293] [EC:3.1.4.53]
PF3D7_1436900  histidine triad protein, putative [KO:K01522] [EC:3.6.1.29]
PF3D7_1440500  allantoicase, putative [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pfa00030  Pentose phosphate pathway
pfa00220  Arginine biosynthesis
pfa00250  Alanine, aspartate and glutamate metabolism
pfa00260  Glycine, serine and threonine metabolism
pfa00630  Glyoxylate and dicarboxylate metabolism
pfa00730  Thiamine metabolism
pfa00740  Riboflavin metabolism
pfa00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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