KEGG   PATHWAY: piz00230
Entry
piz00230                    Pathway                                
Name
Purine metabolism - Pseudomonas izuensis
Class
Metabolism; Nucleotide metabolism
Pathway map
piz00230  Purine metabolism
piz00230

Module
piz_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:piz00230]
piz_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:piz00230]
piz_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:piz00230]
piz_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:piz00230]
piz_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:piz00230]
piz_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:piz00230]
piz_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:piz00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas izuensis [GN:piz]
Gene
LAB08_R02480  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
LAB08_R02490  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
LAB08_R04420  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
LAB08_R04540  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
LAB08_R04560  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
LAB08_R04850  [KO:K01939] [EC:6.3.4.4]
LAB08_R05420  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
LAB08_R05430  [KO:K01429] [EC:3.5.1.5]
LAB08_R05460  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
LAB08_R05710  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
LAB08_R05720  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
LAB08_R06320  [KO:K21053] [EC:3.5.4.2]
LAB08_R08000  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
LAB08_R08010  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
LAB08_R09260  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
LAB08_R09550  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
LAB08_R09630  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
LAB08_R09650  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
LAB08_R09660  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
LAB08_R10560  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
LAB08_R11120  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
LAB08_R12910  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
LAB08_R15080  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
LAB08_R15510  [KO:K16841] [EC:5.1.99.3]
LAB08_R16160  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
LAB08_R16180  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
LAB08_R16190  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
LAB08_R16330  [KO:K00759] [EC:2.4.2.7]
LAB08_R18040  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
LAB08_R30060  [KO:K01835] [EC:5.4.2.2]
LAB08_R36450  [KO:K16842] [EC:3.5.2.5]
LAB08_R37090  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
LAB08_R37650  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
LAB08_R39370  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
LAB08_R40860  [KO:K03787] [EC:3.1.3.5 3.1.3.6]
LAB08_R40930  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
LAB08_R43000  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
LAB08_R43210  [KO:K01129] [EC:3.1.5.1]
LAB08_R43550  [KO:K01081] [EC:3.1.3.5]
LAB08_R44160  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
LAB08_R44170  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
LAB08_R44180  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
LAB08_R44190  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
LAB08_R44200  [KO:K01483] [EC:4.3.2.3]
LAB08_R44960  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
LAB08_R44970  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
LAB08_R46740  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
LAB08_R46750  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
LAB08_R47040  [KO:K00525] [EC:1.17.4.1]
LAB08_R47550  [KO:K00526] [EC:1.17.4.1]
LAB08_R51270  [KO:K00760] [EC:2.4.2.8]
LAB08_R51480  [KO:K00948] [EC:2.7.6.1]
LAB08_R52460  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
LAB08_R53480  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
LAB08_R55390  [KO:K01525] [EC:3.6.1.41]
LAB08_R57160  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
LAB08_R58380  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
LAB08_R58630  [KO:K05851] [EC:4.6.1.1]
LAB08_R58860  [KO:K03816] [EC:2.4.2.22]
LAB08_R59070  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
LAB08_R59140  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
LAB08_R59160  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
LAB08_R59690  [KO:K01589] [EC:6.3.4.18]
LAB08_R59700  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
piz00030  Pentose phosphate pathway
piz00220  Arginine biosynthesis
piz00250  Alanine, aspartate and glutamate metabolism
piz00260  Glycine, serine and threonine metabolism
piz00340  Histidine metabolism
piz00630  Glyoxylate and dicarboxylate metabolism
piz00730  Thiamine metabolism
piz00740  Riboflavin metabolism
piz00790  Folate biosynthesis
KO pathway
ko00230   

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