KEGG   PATHWAY: psc00230
Entry
psc00230                    Pathway                                
Name
Purine metabolism - Stutzerimonas stutzeri CCUG 29243
Class
Metabolism; Nucleotide metabolism
Pathway map
psc00230  Purine metabolism
psc00230

Module
psc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:psc00230]
psc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:psc00230]
psc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:psc00230]
psc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:psc00230]
psc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:psc00230]
psc_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:psc00230]
psc_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:psc00230]
Other DBs
GO: 0006163 0042278
Organism
Stutzerimonas stutzeri CCUG 29243 [GN:psc]
Gene
A458_02435  nudF; ADP-ribose pyrophosphatase NudF [KO:K01515] [EC:3.6.1.13 3.6.1.-]
A458_19825  nudE; adenosine nucleotide hydrolase NudE [KO:K08312] [EC:3.6.1.-]
A458_00245  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
A458_19045  phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
A458_17505  phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
A458_04730  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
A458_11855  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
A458_04280  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
A458_14825  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
A458_15815  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
A458_15850  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
A458_14820  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
A458_20255  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
A458_20260  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
A458_14610  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
A458_09255  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
A458_04285  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
A458_11695  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
A458_08415  surE; 5'(3')-nucleotidase/polyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
A458_19830  HAD superfamily hydrolase [KO:K20881] [EC:3.1.3.-]
A458_11510  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
A458_03235  multi-copper polyphenol oxidoreductase, laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
A458_04795  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
A458_05595  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
A458_05470  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
A458_08465  nucleoside-triphosphatase [KO:K01519] [EC:3.6.1.66]
A458_01435  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
A458_18955  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
A458_05245  xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
A458_05240  xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
A458_17850  putative xanthine dehydrogenase YagR molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
A458_17120  aldehyde oxidase and xanthine dehydrogenase family protein [KO:K11177] [EC:1.17.1.4]
A458_17845  oxidoreductase, molybdopterin-binding subunit [KO:K11178] [EC:1.17.1.4]
A458_17125  oxidoreductase, molybdopterin-binding subunit [KO:K11178] [EC:1.17.1.4]
A458_17840  (2Fe-2S)-binding domain-containing protein [KO:K13483]
A458_17130  iron-sulfur cluster-binding protein [KO:K13483]
A458_20220  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
A458_05600  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
A458_05230  guanine deaminase [KO:K01487] [EC:3.5.4.3]
A458_19090  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
A458_20805  ribonucleotide reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
A458_08795  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
A458_08790  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
A458_14150  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
A458_12675  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
A458_08510  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
A458_06775  hypothetical protein [KO:K06952] [EC:3.1.3.89]
A458_19100  guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
A458_18675  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
A458_08995  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
A458_18515  hypothetical protein [KO:K07816] [EC:2.7.6.5]
A458_08780  hypothetical protein [KO:K07816] [EC:2.7.6.5]
A458_13085  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
A458_18815  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
A458_03135  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
A458_02760  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
A458_20790  decarboxylase family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
A458_03385  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
A458_14400  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
A458_09000  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
A458_02445  Ser/Thr protein phosphatase [KO:K03651] [EC:3.1.4.53]
A458_18395  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
A458_16505  bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein [KO:K00955] [EC:2.7.7.4 2.7.1.25]
A458_16510  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
A458_05105  transthyretin family protein [KO:K07127] [EC:3.5.2.17]
A458_05185  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
A458_05175  hypothetical protein [KO:K13485] [EC:4.1.1.97]
A458_05180  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
A458_05170  allantoicase [KO:K01477] [EC:3.5.3.4]
A458_05165  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
A458_02830  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
A458_02835  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
A458_02845  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
psc00030  Pentose phosphate pathway
psc00220  Arginine biosynthesis
psc00250  Alanine, aspartate and glutamate metabolism
psc00260  Glycine, serine and threonine metabolism
psc00340  Histidine metabolism
psc00630  Glyoxylate and dicarboxylate metabolism
psc00730  Thiamine metabolism
psc00740  Riboflavin metabolism
psc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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