KEGG   PATHWAY: ptro00230
Entry
ptro00230                   Pathway                                
Name
Purine metabolism - Paraburkholderia tropica
Class
Metabolism; Nucleotide metabolism
Pathway map
ptro00230  Purine metabolism
ptro00230

Module
ptro_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ptro00230]
ptro_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ptro00230]
ptro_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ptro00230]
ptro_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ptro00230]
ptro_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ptro00230]
ptro_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ptro00230]
ptro_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ptro00230]
Other DBs
GO: 0006163 0042278
Organism
Paraburkholderia tropica [GN:ptro]
Gene
G5S35_01475  [KO:K00948] [EC:2.7.6.1]
G5S35_01570  [KO:K00759] [EC:2.4.2.7]
G5S35_01940  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
G5S35_02065  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
G5S35_02505  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
G5S35_02730  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
G5S35_02735  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
G5S35_03025  [KO:K01525] [EC:3.6.1.41]
G5S35_03180  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
G5S35_03225  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
G5S35_03270  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
G5S35_03275  [KO:K01429] [EC:3.5.1.5]
G5S35_03280  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
G5S35_03390  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
G5S35_03395  [KO:K00956] [EC:2.7.7.4]
G5S35_04355  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
G5S35_04570  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
G5S35_04905  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
G5S35_05170  [KO:K00988] [EC:2.7.7.5 2.7.7.53]
G5S35_05395  [KO:K00951] [EC:2.7.6.5]
G5S35_05585  [KO:K03651] [EC:3.1.4.53]
G5S35_06030  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
G5S35_06100  [KO:K01939] [EC:6.3.4.4]
G5S35_06610  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
G5S35_06620  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
G5S35_06670  [KO:K16841] [EC:5.1.99.3]
G5S35_06675  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
G5S35_06680  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
G5S35_06685  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
G5S35_06690  [KO:K01483] [EC:4.3.2.3]
G5S35_06725  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
G5S35_07360  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
G5S35_07630  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
G5S35_07680  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
G5S35_09690  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
G5S35_10615  [KO:K21053] [EC:3.5.4.2]
G5S35_10625  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
G5S35_10710  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
G5S35_10720  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
G5S35_10735  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
G5S35_11200  [KO:K11175] [EC:2.1.2.2]
G5S35_11430  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
G5S35_11840  [KO:K01589] [EC:6.3.4.18]
G5S35_11845  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
G5S35_11850  [KO:K01923] [EC:6.3.2.6]
G5S35_12345  [KO:K01081] [EC:3.1.3.5]
G5S35_12420  [KO:K00856] [EC:2.7.1.20]
G5S35_12435  [KO:K00526] [EC:1.17.4.1]
G5S35_12440  [KO:K00525] [EC:1.17.4.1]
G5S35_12465  [KO:K00760] [EC:2.4.2.8]
G5S35_13175  [KO:K01129] [EC:3.1.5.1]
G5S35_14580  [KO:K01951] [EC:6.3.5.2]
G5S35_15720  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
G5S35_18705  [KO:K00525] [EC:1.17.4.1]
G5S35_19360  [KO:K13483]
G5S35_19365  [KO:K11178] [EC:1.17.1.4]
G5S35_19370  [KO:K11177] [EC:1.17.1.4]
G5S35_19635  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
G5S35_21650  [KO:K16856] [EC:4.3.2.3]
G5S35_22110  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
G5S35_22475  [KO:K01241] [EC:3.2.2.4]
G5S35_22995  [KO:K16856] [EC:4.3.2.3]
G5S35_26520  [KO:K03651] [EC:3.1.4.53]
G5S35_29935  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
G5S35_30155  [KO:K22602] [EC:3.5.1.126]
G5S35_35775  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
G5S35_36305  [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ptro00030  Pentose phosphate pathway
ptro00220  Arginine biosynthesis
ptro00250  Alanine, aspartate and glutamate metabolism
ptro00260  Glycine, serine and threonine metabolism
ptro00340  Histidine metabolism
ptro00630  Glyoxylate and dicarboxylate metabolism
ptro00730  Thiamine metabolism
ptro00740  Riboflavin metabolism
ptro00790  Folate biosynthesis
KO pathway
ko00230   

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