 | | PATHWAY: rn00627 | |
| Entry |
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| Name |
Aminobenzoate degradation |
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| Class |
Metabolism; Xenobiotics biodegradation and metabolism
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| Pathway map |
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| Module |
| M00637 | Anthranilate degradation, anthranilate => catechol [PATH:rn00627] |
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| Other DBs |
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| Reaction |
| R00815 | phenol,NADPH:oxogen oxidoreductase (2-hydroxylating) |
| R00821 | 2,3-dihydroxybenzoate carboxy-lyase |
| R00823 | anthranilate,NADH:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating) |
| R00825 | anthranilate,NADPH:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating) |
| R00980 | anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating) |
| R00982 | anthranilate:CoA ligase (AMP-forming) |
| R01238 | 4-hydroxybenzoate carboxy-lyase (phenol-forming) |
| R01293 | 4-hydroxybenzaldehyde:NAD+ oxidoreductase |
| R01294 | 4-hydroxybenzaldehyde:NADP+ oxidoreductase |
| R01295 | benzoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating) |
| R01300 | 4-hydroxybenzoate:CoA ligase (AMP-forming) |
| R01419 | benzaldehyde:NAD+ oxidoreductase |
| R01420 | benzaldehyde:NADP+ oxidoreductase |
| R01421 | benzoyl phosphate phosphohydrolase |
| R01422 | benzoate:CoA ligase (AMP-forming) |
| R01632 | protocatechuate:oxygen 4,5-oxidoreductase (decyclizing) |
| R01764 | benzoylformate carboxy-lyase (benzaldehyde-forming) |
| R02561 | 4-aminobenzoate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating) |
| R02562 | 4-aminobenzoate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating) |
| R02672 | 4-hydroxybenzoylformate carboxy-lyase |
| R02673 | (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase |
| R02877 | vanillyl alcohol:oxygen oxidoreductase |
| R03023 | 4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating) |
| R03024 | 4-nitrophenyl phosphate phosphohydrolase |
| R03026 | (S)-3-hydroxybutanoyl-CoA hydro-lyase |
| R03794 | (S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) |
| R03998 | anthranilyl-CoA,NADH:oxygen oxidoreductase (de-aromatizing) |
| R03999 | anthranilyl-CoA,NADH:oxygen oxidoreductase (de-aromatizing) |
| R04277 | 2-pyrone-4,6-dicarboxylate lactonohydrolase |
| R04278 | 2-hydroxy-2-hydropyrone-4,6-dicarboxylate:NAD+ 6-oxidoreductase |
| R04279 | 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal:NADP+ 2-oxidoreductase |
| R04280 | 3-O-methylgallate:oxygen 4,5-oxidoreductase (decyclizing) |
| R04297 | 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase |
| R05244 | NADPH:p-benzoquinone oxidoreductase |
| R05258 | 4-nitrophenol,NADPH:oxygen 4-oxidoreductase (4-hydroxylating, nitrite-forming) |
| R05259 | parathion,NADPH---hemoprotein reductase:oxygen oxidoreductase (paraoxon-forming) |
| R05274 | vanillate:oxygen oxidoreductase (demethylating) |
| R05308 | dihydrophloroglucinol:NADP+ oxidoreductase |
| R05316 | benzoyl-CoA:acceptor oxidoreductase |
| R05383 | (hydroxyamino)benzene hydroxymutase |
| R05399 | NADH:2-hydroxy-1,4-benzoquinone oxidoreductase |
| R05400 | hydroxylaminobenzene:NADP+ oxidoreductase |
| R05401 | nitrosobenzene:NADP+ oxidoreductase |
| R05405 | 2-aminophenol:oxygen 1,6-oxidoreductase (decyclizing) |
| R05420 | 4-sulfomuconolactone sulfohydrolase |
| R05590 | acylamide aminohydrolase |
| R05603 | 4-hydroxybenzoate carboxy-lyase (phenyl phosphate-forming) |
| R05625 | ATP:phenol phosphotransferase (AMP-forming) |
| R05699 | vanillin:NAD oxidoreductase |
| R06988 | 3-(hydroxyamino)phenol hydroxymutase |
| R07664 | (S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase |
| R07706 | nitrobenzene 1,2-dioxygenase |
| R07832 | 3-hydroxy-5-oxohexanoyl-CoA:acetate CoA-transferase |
| R09270 | syringate:tetrahydrofolate N-methyltransferase |
| R09271 | 3-O-methylgallate:tetrahydrofolate O-methyltransferase |
| R09272 | 3-O-methylgallate:oxygen 3,4-oxidoreductase (decyclizing) |
| R09273 | 4-carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate acylhydrolase |
| R09275 | 5,5'-dehydrodivanillate,NADPH:oxygen oxidoreductase (demethylating) |
| R09276 | 2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl:oxygen 1,2-oxidoreductase (decyclizing) |
| R09277 | 4-[2-(5-carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate 5-carboxy-2-hydroxy-3-methoxybenzoylhydrolase |
| R09278 | 5-carboxyvanillate 5-carboxy-lyase (vanillate-forming) |
| R09284 | 3-(hydroxyamino)phenol hydroxymutase |
| R09288 | 3-hydroxyaminophenol:NAD+ oxidoreductase |
| R09565 | gallate:oxygen oxidoreductase |
| R10136 | vanillate:tetrahydrofolate O-methyltransferase |
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| Compound |
| C00755 | 4-Hydroxy-3-methoxy-benzaldehyde |
| C01108 | 1,2,3-Trihydroxybenzene |
| C01144 | (S)-3-Hydroxybutanoyl-CoA |
| C02137 | alpha-Oxo-benzeneacetic acid |
| C03360 | 4-Nitrophenyl phosphate |
| C03590 | 4-Hydroxyphenylglyoxylate |
| C03671 | 2-Pyrone-4,6-dicarboxylate |
| C03824 | 2-Aminomuconate semialdehyde |
| C04434 | (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate |
| C04484 | 4-Carboxy-2-hydroxymuconate semialdehyde |
| C05165 | 2-Amino-5-oxocyclohex-1-enecarbonyl-CoA |
| C06335 | 4-Aminobenzenesulfonate |
| C06607 | Diethylthiophosphoric acid |
| C06673 | 4-Carboxy-4'-sulfoazobenzene |
| C07103 | 2-Hydroxy-1,4-benzoquinone |
| C16235 | o-Hydroxylaminobenzoate |
| C16267 | Cyclopropanecarboxylate |
| C16268 | Cyclopropanecarboxyl-CoA |
| C16272 | 3-Hydroxy-5-oxohexanoate |
| C16273 | 3-Hydroxy-5-oxohexanoyl-CoA |
| C16285 | Thiobenzamide S,S-dioxide |
| C18345 | 4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate |
| C18347 | 5,5'-Dehydrodivanillate |
| C18348 | 2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl |
| C18349 | 4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate |
| C23074 | 4-Hydroxylaminobenzoate |
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| Reference |
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| Authors |
Fewson CA |
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| Title |
Microbial metabolism of mandelate: a microcosm of diversity. |
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| Journal |
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| Reference |
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| Authors |
McLeish MJ, Kneen MM, Gopalakrishna KN, Koo CW, Babbitt PC, Gerlt JA, Kenyon GL |
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| Title |
Identification and characterization of a mandelamide hydrolase and an NAD(P)+-dependent benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633. |
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| Journal |
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| Reference |
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| Authors |
Shimao M, Nakamura T, Okuda A, Harayama S. |
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| Title |
Characteristics of transposon insertion mutants of mandelic acid-utilizing Pseudomonas putida strain A10L. |
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| Journal |
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| Reference |
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| Authors |
Naidu D, Ragsdale SW. |
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| Title |
Characterization of a three-component vanillate O-demethylase from Moorella thermoacetica. |
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| Journal |
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| Reference |
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| Authors |
Toraya T, Oka T, Ando M, Yamanishi M, Nishihara H. |
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| Title |
Novel pathway for utilization of cyclopropanecarboxylate by Rhodococcus rhodochrous. |
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| Journal |
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Related
pathway |
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| KO pathway |
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