KEGG   PATHWAY: sfiy00630
Entry
sfiy00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces finlayi
Class
Metabolism; Carbohydrate metabolism
Pathway map
sfiy00630  Glyoxylate and dicarboxylate metabolism
sfiy00630

Module
sfiy_M00621  Glycine cleavage system [PATH:sfiy00630]
sfiy_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sfiy00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces finlayi [GN:sfiy]
Gene
F0344_04260  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
F0344_04515  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
F0344_19465  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
F0344_04380  malate synthase A [KO:K01638] [EC:2.3.3.9]
F0344_13325  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
F0344_14820  citrate synthase [KO:K01647] [EC:2.3.3.1]
F0344_23660  citrate synthase [KO:K01647] [EC:2.3.3.1]
F0344_05645  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
F0344_02850  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
F0344_04965  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
F0344_09815  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
F0344_20900  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
F0344_21955  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
F0344_26620  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
F0344_28320  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
F0344_33675  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
F0344_09820  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
F0344_03865  protein meaA [KO:K14447] [EC:5.4.99.63]
F0344_12820  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
F0344_12800  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
F0344_12805  acyl-CoA carboxylase subunit epsilon [KO:K27095]
F0344_33455  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
F0344_33460  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
F0344_13110  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
F0344_22835  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
F0344_35075  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
F0344_01410  catalase [KO:K03781] [EC:1.11.1.6]
F0344_04485  catalase [KO:K03781] [EC:1.11.1.6]
F0344_10985  catalase [KO:K03781] [EC:1.11.1.6]
F0344_15130  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
F0344_19700  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
F0344_27165  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
F0344_27360  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
F0344_27435  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
F0344_30420  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
F0344_09455  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
F0344_09970  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
F0344_31590  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
F0344_09445  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
F0344_27510  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
F0344_33110  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
F0344_09450  gcvH; glycine cleavage system protein GcvH [KO:K02437]
F0344_04490  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
F0344_04475  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
F0344_04480  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
F0344_03925  glycerate kinase [KO:K00865] [EC:2.7.1.165]
F0344_26900  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
F0344_10440  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
F0344_14750  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sfiy00010  Glycolysis / Gluconeogenesis
sfiy00020  Citrate cycle (TCA cycle)
sfiy00030  Pentose phosphate pathway
sfiy00053  Ascorbate and aldarate metabolism
sfiy00071  Fatty acid degradation
sfiy00230  Purine metabolism
sfiy00250  Alanine, aspartate and glutamate metabolism
sfiy00260  Glycine, serine and threonine metabolism
sfiy00620  Pyruvate metabolism
sfiy00710  Carbon fixation by Calvin cycle
sfiy00750  Vitamin B6 metabolism
sfiy00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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