KEGG   PATHWAY: sfiy00230
Entry
sfiy00230                   Pathway                                
Name
Purine metabolism - Streptomyces finlayi
Class
Metabolism; Nucleotide metabolism
Pathway map
sfiy00230  Purine metabolism
sfiy00230

Module
sfiy_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sfiy00230]
sfiy_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sfiy00230]
sfiy_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sfiy00230]
sfiy_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sfiy00230]
sfiy_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sfiy00230]
sfiy_M00546  Purine degradation, xanthine => urea [PATH:sfiy00230]
sfiy_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sfiy00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces finlayi [GN:sfiy]
Gene
F0344_33445  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
F0344_21745  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
F0344_16350  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
F0344_16430  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
F0344_13360  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
F0344_16375  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
F0344_16385  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
F0344_16380  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
F0344_16345  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
F0344_22080  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
F0344_22085  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
F0344_16415  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
F0344_31985  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
F0344_13355  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
F0344_31010  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
F0344_15935  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
F0344_23185  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
F0344_12845  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
F0344_27975  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
F0344_20200  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
F0344_13610  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
F0344_13615  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
F0344_07495  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
F0344_24920  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
F0344_22940  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
F0344_32005  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13481] [EC:1.17.1.4]
F0344_32000  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
F0344_13555  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
F0344_31240  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
F0344_31185  guanylate kinase [KO:K00942] [EC:2.7.4.8]
F0344_07120  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
F0344_10830  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
F0344_10835  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
F0344_25545  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
F0344_07175  HD domain-containing protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
F0344_31015  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
F0344_20435  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
F0344_21895  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
F0344_12790  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
F0344_16225  CYTH domain-containing protein [KO:K05873] [EC:4.6.1.1]
F0344_18995  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
F0344_27600  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
F0344_12925  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
F0344_14065  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
F0344_25275  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
F0344_28400  twin-arginine translocation signal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
F0344_07340  hypothetical protein [KO:K00939] [EC:2.7.4.3]
F0344_13845  adenylate kinase [KO:K00939] [EC:2.7.4.3]
F0344_30930  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
F0344_05040  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
F0344_05050  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
F0344_05045  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
F0344_04425  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
F0344_04430  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
F0344_04435  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
F0344_13195  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
F0344_04360  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
F0344_04355  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
F0344_09185  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
F0344_32115  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
F0344_32110  urease subunit beta [KO:K01429] [EC:3.5.1.5]
F0344_32105  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
F0344_09190  ureA; urease subunit gamma [KO:K14048] [EC:3.5.1.5]
F0344_01000  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sfiy00030  Pentose phosphate pathway
sfiy00220  Arginine biosynthesis
sfiy00250  Alanine, aspartate and glutamate metabolism
sfiy00260  Glycine, serine and threonine metabolism
sfiy00340  Histidine metabolism
sfiy00630  Glyoxylate and dicarboxylate metabolism
sfiy00730  Thiamine metabolism
sfiy00740  Riboflavin metabolism
sfiy00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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