KEGG   PATHWAY: sma00620
Entry
sma00620                    Pathway                                
Name
Pyruvate metabolism - Streptomyces avermitilis
Class
Metabolism; Carbohydrate metabolism
Pathway map
sma00620  Pyruvate metabolism
sma00620

Module
sma_M00168  CAM (Crassulacean acid metabolism), dark [PATH:sma00620]
sma_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sma00620]
sma_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sma00620]
Other DBs
GO: 0006090
Organism
Streptomyces avermitilis [GN:sma]
Gene
SAVERM_1141  adhA1; putative alcohol dehydrogenase [KO:K13953] [EC:1.1.1.1]
SAVERM_1187  aldH; putative aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SAVERM_1242  [KO:K00626] [EC:2.3.1.9]
SAVERM_1357  adhA2; putative alcohol dehydrogenase [KO:K00001] [EC:1.1.1.1]
SAVERM_1514  maeA1; putative malate dehydrogenase (oxaloacetate-decarboxylating; NAD-requiring) [KO:K00027] [EC:1.1.1.38]
SAVERM_1681  fadA4; putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SAVERM_2000  aceB1; putative malate synthase [KO:K01638] [EC:2.3.3.9]
SAVERM_2031  acsA4; putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SAVERM_2044  aceB2; putative malate synthase [KO:K01638] [EC:2.3.3.9]
SAVERM_2079  poxB2; putative pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors [KO:K00156] [EC:1.2.5.1]
SAVERM_2154  lpdA2; putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SAVERM_2659  acyP; putative acylphosphatase [KO:K01512] [EC:3.6.1.7]
SAVERM_2710  leuA1; putative 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
SAVERM_2823  pta; putative phosphotransacetylase [KO:K13788] [EC:2.3.1.8]
SAVERM_2824  ackA; putative acetate kinase [KO:K00925] [EC:2.7.2.1]
SAVERM_2825  pykA1; putative pyruvate kinase [KO:K00873] [EC:2.7.1.40]
SAVERM_2856  fadA1; putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SAVERM_2981  maeB1; putative malate dehydrogenase (oxaloacetate-decarboxylating; NADP-requiring) [KO:K00027] [EC:1.1.1.38]
SAVERM_3218  fumB; putative fumarate hydratase class I [KO:K01676] [EC:4.2.1.2]
SAVERM_3221  fumC; putative fumarate hydratase C [KO:K01679] [EC:4.2.1.2]
SAVERM_3287  pckA; putative phosphoenolpyruvate carboxykinase [KO:K01596] [EC:4.1.1.32]
SAVERM_3314  adhA4; putative NADP-dependent alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
SAVERM_3337  accA3; putative acyl-CoA carboxylase, alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
SAVERM_3347  [KO:K00128] [EC:1.2.1.3]
SAVERM_339  ldhA; putative lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
SAVERM_3436  mdh; putative malate/lactate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SAVERM_3512  fadA2; putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SAVERM_3566  ppc; putative phosphoenolpyruvate carboxylase [KO:K01595] [EC:4.1.1.31]
SAVERM_3828  [KO:K24012]
SAVERM_3870  maeA2; putative malate dehydrogenase (oxaloacetate-decarboxylating; NAD-requiring) [KO:K00027] [EC:1.1.1.38]
SAVERM_4599  acsA1; putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SAVERM_4650  [KO:K00128] [EC:1.2.1.3]
SAVERM_4876  korB; putative 2-oxoglutarate ferredoxin oxidoreductase, beta subunit [KO:K00175] [EC:1.2.7.3 1.2.7.11]
SAVERM_4877  korA; putative 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit [KO:K00174] [EC:1.2.7.3 1.2.7.11]
SAVERM_5126  maeB2; putative malate dehydrogenase (oxaloacetate-decarboxylating; NADP-requiring) [KO:K00027] [EC:1.1.1.38]
SAVERM_5601  leuA2; putative 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
SAVERM_5654  ppdK; putative pyruvate phosphate dikinase [KO:K01006] [EC:2.7.9.1]
SAVERM_5800  aceE1; putative pyruvate dehydrogenase E1 component [KO:K00163] [EC:1.2.4.1]
SAVERM_5852  [KO:K00128] [EC:1.2.1.3]
SAVERM_5871  [KO:K00121] [EC:1.1.1.284 1.1.1.1]
SAVERM_6020  aceE2; putative pyruvate dehydrogenase E1 component [KO:K00163] [EC:1.2.4.1]
SAVERM_6022  sucB; putative dihydrolipoamide S-succinyltransferase [KO:K00627] [EC:2.3.1.12]
SAVERM_6024  lpdA1; putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SAVERM_6217  pykA2; putative pyruvate kinase [KO:K00873] [EC:2.7.1.40]
SAVERM_6595  [KO:K00128] [EC:1.2.1.3]
SAVERM_6843  [KO:K01069] [EC:3.1.2.6]
SAVERM_7177  thcA; putative aldehyde dehydrogenase [KO:K00138] [EC:1.2.1.-]
SAVERM_7482  lldA; putative L-lactate 2-monooxygenase [KO:K00467] [EC:1.13.12.4]
SAVERM_955  poxB1; putative pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors [KO:K00156] [EC:1.2.5.1]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
sma00010  Glycolysis / Gluconeogenesis
sma00020  Citrate cycle (TCA cycle)
sma00061  Fatty acid biosynthesis
sma00250  Alanine, aspartate and glutamate metabolism
sma00260  Glycine, serine and threonine metabolism
sma00290  Valine, leucine and isoleucine biosynthesis
sma00300  Lysine biosynthesis
sma00522  Biosynthesis of 12-, 14- and 16-membered macrolides
sma00630  Glyoxylate and dicarboxylate metabolism
sma00640  Propanoate metabolism
sma00650  Butanoate metabolism
sma00760  Nicotinate and nicotinamide metabolism
sma01056  Biosynthesis of type II polyketide backbone
sma01059  Biosynthesis of enediyne antibiotics
KO pathway
ko00620   

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