KEGG   PATHWAY: sspo00230
Entry
sspo00230                   Pathway                                
Name
Purine metabolism - Streptomyces spongiicola
Class
Metabolism; Nucleotide metabolism
Pathway map
sspo00230  Purine metabolism
sspo00230

Module
sspo_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sspo00230]
sspo_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sspo00230]
sspo_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sspo00230]
sspo_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sspo00230]
sspo_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sspo00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces spongiicola [GN:sspo]
Gene
DDQ41_00925  phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
DDQ41_11590  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
DDQ41_14730  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DDQ41_14805  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
DDQ41_00090  hypothetical protein [KO:K11175] [EC:2.1.2.2]
DDQ41_21290  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DDQ41_14750  phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
DDQ41_14760  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
DDQ41_14755  phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
DDQ41_14725  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
DDQ41_08825  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
DDQ41_08820  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
DDQ41_14790  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DDQ41_10595  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DDQ41_21295  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DDQ41_01070  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DDQ41_14355  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
DDQ41_07765  TIGR01457 family HAD-type hydrolase [KO:K02566] [EC:3.1.3.5]
DDQ41_21795  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
DDQ41_03030  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
DDQ41_00675  pyrimidine-specific ribonucleoside hydrolase RihA [KO:K25589] [EC:3.2.2.2 3.2.2.3]
DDQ41_17855  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DDQ41_19290  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
DDQ41_19295  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
DDQ41_12355  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DDQ41_06710  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DDQ41_07910  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
DDQ41_21155  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
DDQ41_11370  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
DDQ41_11450  guanylate kinase [KO:K00942] [EC:2.7.4.8]
DDQ41_23140  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
DDQ41_24450  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
DDQ41_23135  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
DDQ41_06035  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
DDQ41_01065  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DDQ41_24390  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DDQ41_18090  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DDQ41_09105  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DDQ41_21850  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
DDQ41_14675  adenylyl cyclase [KO:K05873] [EC:4.6.1.1]
DDQ41_17140  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
DDQ41_03465  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
DDQ41_27720  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DDQ41_18760  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DDQ41_21710  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DDQ41_06330  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
DDQ41_02625  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
DDQ41_19010  adenylate kinase [KO:K00939] [EC:2.7.4.3]
DDQ41_01150  HIT family hydrolase [KO:K19710] [EC:2.7.7.53]
DDQ41_26410  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
DDQ41_26400  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
DDQ41_26405  sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
DDQ41_27250  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
DDQ41_27245  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
DDQ41_27240  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
DDQ41_21525  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
DDQ41_27300  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
DDQ41_27305  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
DDQ41_03885  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
DDQ41_20585  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
DDQ41_03880  hypothetical protein [KO:K01429] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sspo00030  Pentose phosphate pathway
sspo00220  Arginine biosynthesis
sspo00250  Alanine, aspartate and glutamate metabolism
sspo00260  Glycine, serine and threonine metabolism
sspo00340  Histidine metabolism
sspo00630  Glyoxylate and dicarboxylate metabolism
sspo00730  Thiamine metabolism
sspo00740  Riboflavin metabolism
sspo00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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