KEGG   PATHWAY: umr03250
Entry
umr03250                    Pathway                                
Name
Viral life cycle - HIV-1 - Ursus maritimus (polar bear)
Class
Genetic Information Processing; Information processing in viruses
Pathway map
umr03250  Viral life cycle - HIV-1
umr03250

Organism
Ursus maritimus (polar bear) [GN:umr]
Gene
103656146  BICD1; protein bicaudal D homolog 1 isoform X1 [KO:K18739]
103656225  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
103656600  MDFIC; LOW QUALITY PROTEIN: myoD family inhibitor domain-containing protein [KO:K27688]
103656971  CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 [KO:K14398]
103659212  [KO:K18750] [EC:3.5.4.-]
103659405  TSG101; tumor susceptibility gene 101 protein isoform X1 [KO:K12183]
103660267  FURIN; furin [KO:K01349] [EC:3.4.21.75]
103660626  FEZ1; fasciculation and elongation protein zeta-1 [KO:K25663]
103660820  [KO:K03767] [EC:5.2.1.8]
103661030  SUPT5H; transcription elongation factor SPT5 [KO:K15172]
103661236  RAN; GTP-binding nuclear protein Ran [KO:K07936]
103662172  PSIP1; PC4 and SFRS1-interacting protein isoform X1 [KO:K25057]
103662194  MLLT3; protein AF-9 [KO:K15187]
103662589  [KO:K15183]
103663297  BICD2; protein bicaudal D homolog 2 isoform X1 [KO:K18739]
103663590  MAP1B; microtubule-associated protein 1B [KO:K10429]
103663825  AFF4; AF4/FMR2 family member 4 [KO:K15185]
103665116  NUP153; nuclear pore complex protein Nup153 isoform X1 [KO:K14296]
103665806  CHMP6; charged multivesicular body protein 6 [KO:K12195]
103665999  HGS; hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [KO:K12182]
103667350  SUPT4H1; transcription elongation factor SPT4 [KO:K15171]
103667666  CCNT2; LOW QUALITY PROTEIN: cyclin-T2 [KO:K15188]
103667676  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
103668810  [KO:K04498] [EC:2.3.1.48]
103669281  SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 [KO:K11648]
103669735  SERINC3; serine incorporator 3 isoform X1 [KO:K25661]
103669780  SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 [KO:K22544] [EC:3.1.5.-]
103670450  CDK9; cyclin-dependent kinase 9 [KO:K02211] [EC:2.7.11.22 2.7.11.23]
103670652  RANBP2; E3 SUMO-protein ligase RanBP2 isoform X1 [KO:K12172] [EC:2.3.2.-]
103670964  NELFCD; negative elongation factor C/D isoform X1 [KO:K15181]
103671303  XPO1; exportin-1 [KO:K14290]
103672230  ELL2; RNA polymerase II elongation factor ELL2 isoform X1 [KO:K15183]
103672619  KAT2A; histone acetyltransferase KAT2A isoform X1 [KO:K06062] [EC:2.3.1.48]
103673398  MAP1A; microtubule-associated protein 1A [KO:K10429]
103673526  ELL3; RNA polymerase II elongation factor ELL3 isoform X1 [KO:K15183]
103673616  VPS4A; vacuolar protein sorting-associated protein 4A isoform X1 [KO:K12196]
103674159  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
103674452  CHMP4B; charged multivesicular body protein 4b [KO:K12194]
103674567  PPIA; peptidyl-prolyl cis-trans isomerase A [KO:K03767] [EC:5.2.1.8]
103674885  CCR5; C-C chemokine receptor type 5 [KO:K04180]
103674936  ELL; RNA polymerase II elongation factor ELL [KO:K15183]
103674956  BST2; bone marrow stromal antigen 2 [KO:K06731]
103675171  MAP1S; microtubule-associated protein 1S [KO:K10429]
103675255  NELFB; negative elongation factor B [KO:K15180]
103675444  CCNT1; cyclin-T1 [KO:K15188]
103675825  VPS4B; vacuolar protein sorting-associated protein 4B [KO:K12196]
103676525  [KO:K18750] [EC:3.5.4.-]
103676647  TNPO3; transportin-3 isoform X1 [KO:K15436]
103676976  NELFA; negative elongation factor A isoform X1 [KO:K15179]
103678163  CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform X5 [KO:K14398]
103678740  PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [KO:K09578] [EC:5.2.1.8]
103679286  CHMP4A; charged multivesicular body protein 4a [KO:K12194]
103679428  [KO:K03767] [EC:5.2.1.8]
103680048  [KO:K10648] [EC:2.3.2.27]
103680723  [KO:K14754]
103680726  [KO:K14754]
103681381  [KO:K18750] [EC:3.5.4.-]
103681499  SERINC5; serine incorporator 5 [KO:K25655]
103681863  MLLT1; protein ENL [KO:K15187]
103681930  KAT2B; histone acetyltransferase KAT2B [KO:K06062] [EC:2.3.1.48]
103682235  [KO:K12200]
103682286  NELFE; negative elongation factor E [KO:K15182]
121106081  [KO:K03767] [EC:5.2.1.8]
Reference
  Authors
Li G, De Clercq E
  Title
HIV Genome-Wide Protein Associations: a Review of 30 Years of Research.
  Journal
Microbiol Mol Biol Rev 80:679-731 (2016)
DOI:10.1128/MMBR.00065-15
Reference
  Authors
Tagliamonte M, Tornesello ML, Buonaguro FM, Buonaguro L
  Title
Conformational HIV-1 envelope on particulate structures: a tool for chemokine coreceptor binding studies.
  Journal
J Transl Med 9 Suppl 1:S1 (2011)
DOI:10.1186/1479-5876-9-S1-S1
Reference
  Authors
Novikova M, Zhang Y, Freed EO, Peng K
  Title
Multiple Roles of HIV-1 Capsid during the Virus Replication Cycle.
  Journal
Virol Sin 34:119-134 (2019)
DOI:10.1007/s12250-019-00095-3
Reference
  Authors
Rawle DJ, Harrich D
  Title
Toward the "unravelling" of HIV: Host cell factors involved in HIV-1 core uncoating.
  Journal
PLoS Pathog 14:e1007270 (2018)
DOI:10.1371/journal.ppat.1007270
Reference
  Authors
Le Sage V, Mouland AJ, Valiente-Echeverria F
  Title
Roles of HIV-1 capsid in viral replication and immune evasion.
  Journal
Virus Res 193:116-29 (2014)
DOI:10.1016/j.virusres.2014.07.010
Reference
  Authors
Murphy RE, Saad JS
  Title
The Interplay between HIV-1 Gag Binding to the Plasma Membrane and Env Incorporation.
  Journal
Viruses 12:E548 (2020)
DOI:10.3390/v12050548
Reference
  Authors
He N, Zhou Q
  Title
New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC).
  Journal
J Neuroimmune Pharmacol 6:260-8 (2011)
DOI:10.1007/s11481-011-9267-6
Reference
  Authors
Pincetic A, Leis J
  Title
The Mechanism of Budding of Retroviruses From Cell Membranes.
  Journal
Adv Virol 2009:6239691-6239699 (2009)
DOI:10.1155/2009/623969
Reference
  Authors
Kleinpeter AB, Freed EO
  Title
HIV-1 Maturation: Lessons Learned from Inhibitors.
  Journal
Viruses 12:E940 (2020)
DOI:10.3390/v12090940
Reference
  Authors
Young TM, Wang Q, Pe'ery T, Mathews MB
  Title
The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.
  Journal
Mol Cell Biol 23:6373-84 (2003)
DOI:10.1128/MCB.23.18.6373-6384.2003
Related
pathway
umr03013  Nucleocytoplasmic transport
umr04144  Endocytosis
KO pathway
ko03250   

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