KEGG   ORTHOLOGY: K07936
Entry
K07936                      KO                                     
Symbol
RAN
Name
GTP-binding nuclear protein Ran
Pathway
map03008  Ribosome biogenesis in eukaryotes
map03013  Nucleocytoplasmic transport
map03250  Viral life cycle - HIV-1
map05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    K07936  RAN; GTP-binding nuclear protein Ran
   03008 Ribosome biogenesis in eukaryotes
    K07936  RAN; GTP-binding nuclear protein Ran
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    K07936  RAN; GTP-binding nuclear protein Ran
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K07936  RAN; GTP-binding nuclear protein Ran
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K07936  RAN; GTP-binding nuclear protein Ran
   03009 Ribosome biogenesis
    K07936  RAN; GTP-binding nuclear protein Ran
   03016 Transfer RNA biogenesis
    K07936  RAN; GTP-binding nuclear protein Ran
   03036 Chromosome and associated proteins
    K07936  RAN; GTP-binding nuclear protein Ran
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07936  RAN; GTP-binding nuclear protein Ran
   04031 GTP-binding proteins
    K07936  RAN; GTP-binding nuclear protein Ran
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Ran-mediated transport factors
     K07936  RAN; GTP-binding nuclear protein Ran
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-40S particles
   Export and cytoplasmic maturation factors
    K07936  RAN; GTP-binding nuclear protein Ran
  Pre-60S particles
   Export and cytoplasmic maturation factors
    K07936  RAN; GTP-binding nuclear protein Ran
Transfer RNA biogenesis [BR:ko03016]
 Eukaryotic type
  tRNA transport factors
   tRNA export factors
    K07936  RAN; GTP-binding nuclear protein Ran
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     K07936  RAN; GTP-binding nuclear protein Ran
   Spindle formation proteins
    K07936  RAN; GTP-binding nuclear protein Ran
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07936  RAN; GTP-binding nuclear protein Ran
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Ran Family
   Ran
    K07936  RAN; GTP-binding nuclear protein Ran
Genes
HSA: 5901(RAN)
PTR: 452414(RAN)
PPS: 100976346(RAN) 100988742 117975609 117975697
GGO: 101143548(RAN)
PON: 100173539(RAN) 100937596
NLE: 100581875(RAN) 100590022 100592573 100599771
MCC: 709200(RAN)
MCF: 102133660(RAN)
MTHB: 126930550
CSAB: 103218749 103239407(RAN)
CATY: 105591055(RAN)
PANU: 101006459(RAN) 101007107
TGE: 112625116 112634488(RAN)
RRO: 104655552(RAN) 104674363
RBB: 108526883(RAN)
TFN: 117089172(RAN)
CJC: 100400787(RAN)
SBQ: 101043259(RAN) 101046456
CSYR: 103271889(RAN)
MMUR: 105872759(RAN)
LCAT: 123625769(RAN)
OGA: 100941328(RAN)
MMU: 19384(Ran) 19428(Rasl2-9) 75471(1700009N14Rik)
RNO: 313163(RGD1306195) 751812(Rasl2-9) 84509(Ran)
NGI: 103750614(Ran)
HGL: 101711994(Ran)
CCAN: 109695688(Ran)
DORD: 105990688(Ran)
DSP: 122101938(Ran)
NCAR: 124991882
OCU: 100352306(RAN) 100357230
OPI: 101525062(RAN)
TUP: 102500543(RAN)
CFA: 100499482(RAN)
VVP: 112920146 112933832(RAN)
VLG: 121475819(RAN) 121484203
AML: 100468957(RAN) 117799753
UMR: 103661236(RAN)
UAH: 113266861(RAN)
UAR: 123780403(RAN)
LLV: 125082448
MPUF: 101690738(RAN)
NSU: 110588199(RAN)
FCA: 101080666(RAN)
PYU: 121010445(RAN)
PBG: 122470111(RAN)
LRUF: 124522026
PTG: 102954016(RAN)
PPAD: 109257606(RAN)
AJU: 106986939(RAN)
HHV: 120243453(RAN)
BIU: 109562689 109571399(RAN)
SSC: 397655(RAN)
BACU: 103016841(RAN)
LVE: 103070167 103082587(RAN)
OOR: 101281487 101283104(RAN)
PCAD: 102985469(RAN)
ECB: 100062767(RAN)
EPZ: 103560560(RAN)
EAI: 106841835(RAN)
MYB: 102239412(RAN)
MYD: 102754269(RAN)
MMYO: 118653021(RAN)
MLF: 102434289(TMEM41B)
MNA: 107529640(RAN)
DRO: 112308882 112310778(RAN)
AJM: 119060643 119060801(RAN)
PDIC: 114489725(RAN)
PHAS: 123823414(RAN)
MMF: 118640207(RAN)
PALE: 102893000(RAN)
PGIG: 120615984(RAN)
PVP: 105293597 105299564(RAN)
RAY: 107502514 107511541(RAN)
MJV: 108388641(RAN) 108392341
TOD: 119245080(RAN)
SARA: 101551011 101555816(RAN)
LAV: 100655400(RAN) 100669230
TMU: 101345055
DNM: 101435173(RAN)
MDO: 100020008(RAN)
SHR: 100913923(RAN) 100916523
PCW: 110220348(RAN)
OAA: 100090125(RAN)
GGA: 396193(RAN)
PCOC: 116228672(RAN)
MGP: 104913530(RAN)
CJO: 107321272(RAN)
NMEL: 110406273(RAN)
APLA: 101794739(RAN)
ACYG: 106031204(RAN)
AFUL: 116496120(RAN)
TGU: 100190162(RAN)
LSR: 110477846(RAN)
SCAN: 103818200(RAN)
PMOA: 120509685(RAN)
OTC: 121338918(RAN)
PRUF: 121364969(RAN)
GFR: 102040216(RAN)
FAB: 101809752(RAN)
PHI: 102104465(RAN)
PMAJ: 107211879(RAN)
CCAE: 111936334(RAN)
CCW: 104688747(RAN)
CBRC: 103615900(RAN)
ETL: 114061033(RAN)
ZAB: 102065008(RAN)
ACHL: 103805707(RAN)
FPG: 101918787(RAN)
FCH: 102059089(RAN)
CLV: 102091968(RAN)
EGZ: 104127186(RAN)
NNI: 104019840(RAN)
PLET: 104618042(RAN)
PCRI: 104026187(RAN)
ACUN: 113486002(RAN)
TALA: 104365690(RAN)
PADL: 103914331(RAN)
AFOR: 103894859(RAN)
ACHC: 115345463(RAN)
HALD: 104313127(RAN)
CCRI: 104159429(RAN)
CSTI: 104556529(RAN)
EHS: 104508362(RAN)
CMAC: 104474931(RAN)
MUI: 104537207(RAN)
FGA: 104071647(RAN)
GSTE: 104257017(RAN)
LDI: 104345252(RAN)
MNB: 103776854(RAN)
OHA: 104327558(RAN)
NNT: 104412684(RAN)
DPUB: 104309671(RAN)
PGUU: 104463991(RAN)
ACAR: 104524690(RAN)
AVIT: 104269346(RAN)
CVF: 104289190(RAN)
AAM: 106489909(RAN)
AROW: 112962501(RAN)
NPD: 112945908(RAN)
TGT: 104570841(RAN)
DNE: 112980453(RAN)
SCAM: 104138837(RAN)
ASN: 102370450(RAN)
AMJ: 102562653(RAN)
CPOO: 109312996(RAN)
GGN: 109290487(RAN)
PSS: 102446816 102448079(RAN)
CMY: 102931665(RAN)
CPIC: 101952069(RAN)
TST: 117888138(RAN)
CABI: 116839795(RAN)
MRV: 120386007(RAN)
ACS: 100561269(ran)
PVT: 110076603(RAN)
SUND: 121914872 121916658(RAN)
PBI: 103056862(RAN)
PMUR: 107295820(RAN)
CTIG: 120314339(RAN)
TSR: 106549752(RAN)
PGUT: 117658004(RAN)
VKO: 123028692(RAN)
PMUA: 114586337(RAN)
ZVI: 118076349(RAN)
GJA: 107116017(RAN)
STOW: 125442846(RAN)
XLA: 108716335(ran.L) 379874(ran.S)
XTR: 448091(ran)
NPR: 108795534(RAN)
RTEM: 120935402(RAN) 120941026
BBUF: 120988655(RAN) 120993690
BGAR: 122924492(RAN)
DRE: 30572(ran)
SANH: 107661941(ran) 107682846
PPRM: 120460969(ran)
MAMB: 125259066(ran)
IPU: 100528155(ran)
PHYP: 113542941(ran)
SMEO: 124386578(ran)
TFD: 113647824(ran)
AMEX: 103033763(ran)
EEE: 113570736(ran)
TRU: 101070070(ran)
LCO: 104937671(ran)
NCC: 104953376(ran)
CGOB: 115014564(ran)
ELY: 117260558(ran)
EFO: 125894681(ran)
PLEP: 121947659(ran) 121947660
SLUC: 116052408(ran)
ECRA: 117951967(ran)
ESP: 116696347(ran)
PFLV: 114563383(ran)
GAT: 120817455(ran)
PPUG: 119210562(ran)
MSAM: 119888994(ran)
CUD: 121515897(ran)
ALAT: 119008109(ran)
MZE: 101467159(ran)
ONL: 100707444(ran)
OAU: 116332009(ran)
OLA: 101156259(ran)
OML: 112153522(ran)
XMA: 102234897(ran)
XCO: 114138775(ran)
XHE: 116713994(ran)
PRET: 103471374(ran)
PFOR: 103147490(ran)
PLAI: 106938149(ran)
PMEI: 106907038(ran)
GAF: 122836680(ran)
CVG: 107085660(ran)
CTUL: 119788336(ran)
GMU: 124859915(ran)
NFU: 107376735(ran)
KMR: 108243060(ran)
ALIM: 106516424(ran)
NWH: 119408966(ran)
AOCE: 111576486(ran)
MCEP: 125008480(ran)
CSEM: 103390946(ran)
POV: 109628339(ran)
SSEN: 122778957(ran)
HHIP: 117768801(ran)
HSP: 118112607(ran)
LCF: 108878285
SDU: 111232462(ran)
SLAL: 111651316 111662736(ran)
XGL: 120785325(ran)
HCQ: 109524377(ran)
MALB: 109953755(ran)
BSPL: 114864312(ran)
SASA: 100136389(RAN) 100136528(ran1) 100196560(ran) 106609900(RAN)
ELS: 105022884 105028585(ran)
LOC: 102692016 102694382(ran)
LCM: 102364067(RAN)
CMK: 103188021(ran)
RTP: 109923190(ran)
BFO: 118426421
BBEL: 109484118
CIN: 100181477
SPU: 581649
APLC: 110980697
SKO: 100374136
DSI: Dsimw501_GD12564(Dsim_GD12564) Dsimw501_GD22834(Dsim_GD22834) Dsimw501_GD24539(Dsim_GD24539)
DYA: Dyak_GE15102 Dyak_GE17316(Dyak_ran)
CCAT: 101451054
BOD: 106617213
RZE: 108366789
MDE: 101897713
SCAC: 106084150
LCQ: 111685136
LSQ: 119612287
HIS: 119647208
ACOZ: 120953969
AARA: 120902309
AAG: 5571763
CPII: 120429775
CNS: 116345456
BCOO: 119074047
AME: 410280
ACER: 107995624
ALAB: 122717960
BIM: 100747095
BBIF: 117214030
BVK: 117236382
BVAN: 117166785
BTER: 100646748
BPYO: 122573042
CCAL: 108624891
OBB: 114875989
MGEN: 117229773
NMEA: 116428183
CGIG: 122397292
SOC: 105203546
MPHA: 105838998
AEC: 105147439
ACEP: 105622619
PBAR: 105426228
VEM: 105565440
HST: 105183188
DQU: 106747529
CFO: 105247973
FEX: 115243565
LHU: 105673799
PGC: 109855901
OBO: 105279171
PCF: 106789205
PFUC: 122517394
VPS: 122629091
NVI: 100114116
CSOL: 105365474
TPRE: 106649551
MDL: 103569822
CGLO: 123264862
FAS: 105267697
DAM: 107044125
AGIF: 122848176
LHT: 122506041
CCIN: 107272428
TCA: 657695
DPA: 109535166
SOY: 115890766
CSET: 123313687
AGB: 108904059
LDC: 111508394
NVL: 108557121
APLN: 108737653
PPYR: 116175749
OTU: 111429232
BMOR: 692970
MSEX: 115442372
BANY: 112047046
NIQ: 126769876
PMAC: 106720185
PPOT: 106109298
PRAP: 110999455
ZCE: 119834946
HAW: 110372579
HZE: 124631264
TNL: 113491707
OFU: 114354106
API: 100162905(Ran)
DNX: 107163659
AGS: 114132507
RMD: 113554622
CLEC: 106672259
HHAL: 106683346
FOC: 113207906
TPAL: 117645320
ZNE: 110833573
CSEC: 111867160
DMK: 116932489
HAZT: 108682776
LSM: 121116346
DSV: 119446049
RSAN: 119390113
RMP: 119173663
TUT: 107368508
DFR: 124490640
PTEP: 107439373
SDM: 118198923
CEL: CELE_K01G5.4(ran-1)
CBR: CBG_18317(Cbr-ran-1)
BMY: BM_BM4731(Bma-ran-1)
TSP: Tsp_04091
PCAN: 112561744
BGT: 106078432
CRG: 105327885
MMER: 123534829
OBI: 106877227
OSN: 115224235
LAK: 106160330
EGL: EGR_04178
NVE: 5508877
EPA: 110252234
ATEN: 116289667
ADF: 107334559
AMIL: 114960208
PDAM: 113681045
SPIS: 111330112
XEN: 124434680
HMG: 100211661
ATH: AT5G20010(RAN-1) AT5G20020(RAN2) AT5G55080(RAN4) AT5G55190(RAN3)
TCC: 18588700
LJA: Lj0g3v0196629.1(Lj0g3v0196629.1) Lj0g3v0337519.1(Lj0g3v0337519.1) Lj1g3v1912870.1(Lj1g3v1912870.1) Lj4g3v1833610.1(Lj4g3v1833610.1)
RCU: 8278571
SLY: 778289(RAN1) 778290(RAN2A) 778291(RAN2B)
NTA: 107765348(Ran-B2) 107779563(Ran-B1) 107787005(Ran-A2) 107829920(Ran-A1)
DOSA: Os01t0611100-01(Os01g0611100) Os05t0574500-01(Os05g0574500) Os06t0600301-00(Os06g0600301)
OBR: 102709464
PEQ: 110027225
APRO: F751_5979
SCE: YLR293C(GSP1) YOR185C(GSP2)
ERC: Ecym_3097
KMX: KLMA_10225(GSP1) KLMA_50134(GSP1)
NCS: NCAS_0F00440(NCAS0F00440)
NDI: NDAI_0D02670(NDAI0D02670)
TPF: TPHA_0K01060(TPHA0K01060)
TBL: TBLA_0E00980(TBLA0E00980)
TDL: TDEL_0G03810(TDEL0G03810)
KAF: KAFR_0A04800(KAFR0A04800)
KNG: KNAG_0F03180(KNAG0F03180)
CAL: CAALFM_C206310CA(GSP1)
SLB: AWJ20_1622(GSP2)
BNN: FOA43_001572(GSP1)
BBRX: BRETT_001340(GSP2)
NCR: NCU09269(ran)
NTE: NEUTE1DRAFT119293(NEUTE1DRAFT_119293)
MGR: MGG_09952
SSCK: SPSK_05396
TRE: TRIREDRAFT_75547(ran1)
MAW: MAC_05258
MAJ: MAA_03972
CMT: CCM_06188
ANI: AN5482.2
ANG: ANI_1_1342074(An08g10060)
ALUC: AKAW2_51786S(GSP1)
ACHE: ACHE_10147A(GSP1)
APUU: APUU_40813S(GSP1)
ABE: ARB_07546
TVE: TRV_07436
PTE: PTT_04918
SPO: SPBC1289.03c(spi1)
CNE: CNE02890
CNB: CNBE2910
TASA: A1Q1_00836
ABP: AGABI1DRAFT111135(AGABI1DRAFT_111135)
ABV: AGABI2DRAFT190352(AGABI2DRAFT_190352)
MORE: E1B28_008931(GSP1)
SCM: SCHCO_02605647(SCHCODRAFT_02605647)
WSE: WALSEDRAFT_62044(Gsp1p)
MGL: MGL_2972
MRT: MRET_3576
DDI: DDB_G0291235(ranA)
DFA: DFA_02199(ranA)
EHI: EHI_148190(1.t00138)
TAN: TA06865
TPV: TP01_0757
BBO: BBOV_IV010920(23.m06098)
CPV: cgd7_220
SMIN: v1.2.019954.t1(symbB.v1.2.019954.t1) v1.2.029132.t1(symbB.v1.2.029132.t1)
 » show all
Reference
  Authors
Dasso M
  Title
The Ran GTPase: theme and variations.
  Journal
Curr Biol 12:R502-8 (2002)
DOI:10.1016/S0960-9822(02)00970-3
Reference
PMID:8692944
  Authors
Moroianu J, Blobel G, Radu A
  Title
Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta.
  Journal
Proc Natl Acad Sci U S A 93:7059-62 (1996)
DOI:10.1073/pnas.93.14.7059
  Sequence
[hsa:5901]
Reference
PMID:2108320
  Authors
Drivas GT, Shih A, Coutavas E, Rush MG, D'Eustachio P
  Title
Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.
  Journal
Mol Cell Biol 10:1793-8 (1990)
DOI:10.1128/MCB.10.4.1793
  Sequence
[hsa:5901]
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