KEGG ORTHOLOGY: K18750

ORTHOLOGY: K18750

Entry

K18750                      KO

Symbol

APOBEC3

Name

C->U-editing enzyme APOBEC3 [EC:3.5.4.-]

Pathway

map03250

Viral life cycle - HIV-1

map05170

Human immunodeficiency virus 1 infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    K18750  APOBEC3; C->U-editing enzyme APOBEC3
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K18750  APOBEC3; C->U-editing enzyme APOBEC3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K18750  APOBEC3; C->U-editing enzyme APOBEC3
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     K18750  APOBEC3; C->U-editing enzyme APOBEC3

Genes

HSA:	100913187(APOBEC3A_B) 140564(APOBEC3D) 164668(APOBEC3H) 200315(APOBEC3A) 200316(APOBEC3F) 27350(APOBEC3C) 60489(APOBEC3G) 9582(APOBEC3B)

PTR:	100611714(APOBEC3C) 449577(APOBEC3G) 470214(APOBEC3H) 470274(APOBEC3D) 470275(APOBEC3F) 743891(APOBEC3B) 744498(APOBEC3A)

PPS:	100971498(APOBEC3B) 100982453(APOBEC3G) 100983444(APOBEC3C) 100983664(APOBEC3H) 100990514 117977490(APOBEC3A) 117977491(APOBEC3D)

GGO:	101133558(APOBEC3B) 101133902(APOBEC3C) 101134601(APOBEC3F) 101137376(APOBEC3G) 115931928(APOBEC3H) 115931935(APOBEC3D)

PON:	100455142(APOBEC3A) 100456583(APOBEC3B) 100458043(APOBEC3G) 100458762(APOBEC3H) 103888537(APOBEC3C) 129047336

PPYG:

129023577(APOBEC3A) 129023578 129023579(APOBEC3B) 129023580 129023582(APOBEC3G) 129023583(APOBEC3H)

NLE:	100583627 100585149(APOBEC3A) 100585498(APOBEC3D) 100585723(APOBEC3C) 100585834(APOBEC3H) 100601000(APOBEC3G) 108684025(APOBEC3B) 115835901

HMH:	116459220(APOBEC3A) 116459395(APOBEC3C) 116464712 116464846 116465145 116465269 116465334

SSYN:

129467569(APOBEC3H) 129468125 129468126(APOBEC3D) 129468129(APOBEC3A) 129468230 129468233

MCC:	574398(APOBEC3G) 705870(APOBEC3C) 705996(APOBEC3D) 721030(APOBEC3A) 721047(APOBEC3B) 723811(APOBEC3H) 723812(APOBEC3F)

MCF:	101925624(APOBEC3C) 102126615(APOBEC3B) 102127357(APOBEC3D) 102128261(APOBEC3G) 102129411(APOBEC3H) 102131077(APOBEC3A) 107126386

MTHB:

126963734 126963762 126963765 126963768

MNI:	105464427(APOBEC3H) 105464428(APOBEC3G) 105464430 105464431(APOBEC3D) 105464432(APOBEC3F) 105464550 105468310

CSAB:

103223331(APOBEC3D) 103223333(APOBEC3C) 103223334(APOBEC3G) 103223335(APOBEC3H) 103247808 108663998(APOBEC3B)

CATY:

105572988(APOBEC3G) 105573008 105573014(APOBEC3F) 105573020(APOBEC3C) 105573030(APOBEC3B) 105573037(APOBEC3A) 105573250(APOBEC3H)

PANU:

100303423(APOBEC3G) 101008781(APOBEC3A) 101009457(APOBEC3D) 101010266(APOBEC3H) 108663997(APOBEC3F) 108684027(APOBEC3C)

TGE:	112632746 112632747 112632749 112632750(APOBEC3C) 112633208 112633312(APOBEC3H) 112634959

MLEU:

105538859(APOBEC3H) 105538860(APOBEC3F) 105538862 105538863(APOBEC3C) 105538864(APOBEC3B)

RRO:	104682550(APOBEC3H) 104682552(APOBEC3G) 104682553(APOBEC3F) 104682554(APOBEC3D) 104682555(APOBEC3B) 104682557(APOBEC3A) 108684023(APOBEC3C)

RBB:	108520475(APOBEC3G) 108520477(APOBEC3H) 108521436(APOBEC3A) 108521467 108521468 108521469 108526035

TFN:	117070549 117096478 117096479 117096481 117096482(APOBEC3H) 117096485(APOBEC3C)

PTEH:

111530206(APOBEC3G) 111548998(APOBEC3H) 111548999 111549001 111549002

CANG:

105527769 105527770 105527771 105527772 105527837

CJC:	100386727 100387905(APOBEC3A) 100393962 100397263(APOBEC3C) 100397628(APOBEC3G) 100412309(APOBEC3H) 100412662 100413381 100413502 128929074

SBQ:	101035068(APOBEC3H) 101035383 101035696 101036011 101036333 101036976 101047325

CIMI:

108287793 108288795 108289451(APOBEC3C) 108289529 108289530(APOBEC3A) 108306430 108315302 108315303(APOBEC3H)

ANAN:

105721752(APOBEC3C) 105721753 105721799(APOBEC3A) 105721800(APOBEC3G) 105721801(APOBEC3H) 105721803 105726431

CSYR:

103250986 103250987 103250989

MMUR:

105856859 105858492 105858493 109730938

PCOQ:

105805183

OGA:	100950473 100950777 100951096 105887360 105888469

MMU:	80287(Apobec3)

MCAL:

110310320

MPAH:

110334948

RNO:	315137(Apobec3)

MCOC:

116076032

ANU:

117718458

ASYL:

127667574(Apobec3h)

MUN:

110557822

CGE:	100772476(Apobec3b)

MAUA:

101832694

PROB:

127225795(Apobec3b)

PLEU:

MORG:

MFOT:

AAMP:

NGI:

HGL:	101722862 101723345

CPOC:

CCAN:

DORD:

DSP:

PLOP:

NCAR:

MMMA:

ITI:

OCU:	100340649 103348387

OPI:	101520109 101520353

TUP:	102468505 102476613 102477121 102486589(APOBEC3F) 102498341(APOBEC3H)

GVR:	103581391 103581392 103582173 103583284 103583285 103584151 103600466(APOBEC3H)

CFA:	481248(APOBEC3Z3) 610245(APOBEC3Z1)

CLUD:

112675192 112675198

VVP:

112934047

VLG:

121490498

NPO:	129511780 129512091 129512092

AML:	100464783 100483325 100483573

UMR:	103659212 103676525 103681381

UAH:

113251074

UAR:	123780529 123780568

ELK:	111140345 111157577

LLV:	125107011 125107494

MPUF:

101680223

MNP:	132008768 132020229

MLK:	131839490 131839847

NVS:	122891513 122891844 122892338

ORO:	101378154(APOBEC3B) 105757446(APOBEC3H)

EJU:	114203841 114218359

ZCA:	113921548(APOBEC3B)

MLX:	117998666 118026594

NSU:	110578160 110579380

LWW:	102750772(APOBEC3H)

FCA:	100127022(APOBEC3Z3)

PYU:	121024809 121026324 121026344 121040332

PCOO:

112863515

PBG:	122472770 122473689

PVIV:

LRUF:

LGF:

AJU:

PTG:

PPAD:

PUC:

PLEZ:

HHV:	120227638(APOBEC3A) 120234545

BTA:	108771180(APOBEC3H) 504505(APOBEC3Z2) 507162(APOBEC3Z1)

BIU:

109558629

BBUB:

102405577 112584444(APOBEC3A)

BBIS:

104992294 104992295(APOBEC3A)

CHX:	102184324 106502146

OAS:	100037691(APOBEC3F) 100301555(APOBEC3A)

BTAX:

128047831

CSUM:

138077798 138078803

ODA:	120857650(APOBEC3H) 120857653 120857654

CCAD:

122423755(APOBEC3B) 122423756(APOBEC3A)

MREE:

136174148 136174177

OVR:	110129971 110129975

MBEZ:

129535844 129535846

SSC:	100037939(APOBEC3B)

CFR:

102512329

CDK:	105091988 116156504

VPC:

102529953

BACU:

103013586(APOBEC3G) 103014141(APOBEC3B)

BMUS:

118902687 118902688

LVE:	103069082(APOBEC3G) 103086070(APOBEC3B)

OOR:	101273482 105748501

LALB:

132529665 132529668(APOBEC3A)

DLE:	111186177 111186179

PCAD:

102983741 112065878(APOBEC3A)

PSIU:

116760453 116760454

NASI:

112410778 112410812(APOBEC3A)

ECB:	100070206 100070250(APOBEC3Z2A-Z2) 100070262(APOBEC3H) 100146802 100147481(A3F2) 100302571

EPZ:	103545867 103565680(APOBEC3H)

EAI:	106836896 106837629 106837631 123289558 123289590

MYB:	102240642 102253539 102258209 102260004 102260414 106728123

MYD:	102752136 102757825 102768131 102768424

MMYO:

118650760 118650761 118651910 118652089 118664678 118678243 118678285

MLF:	102434062 102435310 102435613 102439233 106695187 106695188 106695661 111824110 111824111

MDT:	132225941 132226943 132226948 132226949 132226950 132226952 132226953 132234757

MYUM:

139002746 139005478 139006533 139006534 139006535 139006536 139006537 139006538

PKL:	118728374 118728567 118728855 118728856 118728857 118728859

EFUS:

103289073 103289074 129149857

MNA:	107531231 107531232

DRO:	112321861 112322019 112322020 112322021

SHON:

119002214 119002215 119002448

AJM:

119060284

PDIC:

114488392 114513938 118498588

PHAS:

123816048 123816049 123816081 123816082 123816189 123816213

MMF:	118623274 118623525 118624427(APOBEC3A)

PPAM:

129077906

HAI:	109392229 109392257(APOBEC3H) 109394478

RFQ:	117028309 117028311 117029321

PALE:

107196052 112484225 112484226

PGIG:

120592783 120592784 120592788 120596571 120596572 120596573 120603008 120603009 120603010 120605431 120613156

PVP:	105288322 105288324 105298104(APOBEC3H) 105309500 105309502 105309845 111734308 111735996

RAY:	107502069 107519218 118613791 118613792

TOD:	119247254 119247255

SARA:

101546977

SFUM:

130044824

LAV:	100662049 100662329 100662891 100663177 104846826

TMU:	101347659 101347905 101348163 105756166

ETF:	101648131 101648441 115869750

DNM:	101426294 111761566

MDO:

103099360

GAS:	123239887 123254429

SHR:

AFZ:

PCW:

TVP:

PBRV:

ACS:

ASAO:

PVT:

SUND:

VKO:

PMUA:

ZVI:

GJA:

XLA:

XTR:

BBUF:

BGAR:

PWL:

HCQ:

SFM:

PKI:

LOC:

PSPA:

ARUT:

117407510 117409991 117414435

PMRN:

116957308

SPIS:

111319975 111319976 111335764

» show all

Reference

PMID:12683974

Authors

Wedekind JE, Dance GS, Sowden MP, Smith HC

Title

Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.

Journal

Trends Genet 19:207-16 (2003)
DOI:10.1016/S0168-9525(03)00054-4

Sequence

[hsa:200315 9582 27350 140564 60489 200316 164668]

Reference

PMID:17166910

Authors

Gallois-Montbrun S, Kramer B, Swanson CM, Byers H, Lynham S, Ward M, Malim MH

Title

Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules.

Journal

J Virol 81:2165-78 (2007)
DOI:10.1128/JVI.02287-06

Sequence

[hsa:60489]

Reference

PMID:10469298

Authors

Madsen P, Anant S, Rasmussen HH, Gromov P, Vorum H, Dumanski JP, Tommerup N, Collins JE, Wright CL, Dunham I, MacGinnitie AJ, Davidson NO, Celis JE

Title

Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1.

Journal

J Invest Dermatol 113:162-9 (1999)
DOI:10.1046/j.1523-1747.1999.00682.x

Sequence

[hsa:200315]

LinkDB

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