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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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Class I HDACs
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106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106836963 HDAC3; histone deacetylase 3 isoform X1
106835298 HDAC8; histone deacetylase 8 isoform X1
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K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
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Class II HDACs
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SIRTs (sirtuins, class III HDACs)
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Class IV HDACs
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HDAC complexes
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Sin3A-HDAC complex
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106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106831283 SIN3A; paired amphipathic helix protein Sin3a
106829040 RBBP4; histone-binding protein RBBP4 isoform X2
106832438 LOW QUALITY PROTEIN: histone-binding protein RBBP4-like
106845829 RBBP7; histone-binding protein RBBP7 isoform X1
106839776 SUDS3; sin3 histone deacetylase corepressor complex component SDS3 isoform X4
106831725 SAP30; histone deacetylase complex subunit SAP30 isoform X3
106834925 SAP30L; histone deacetylase complex subunit SAP30L
106828562 SAP18; histone deacetylase complex subunit SAP18
106841533 SAP130; histone deacetylase complex subunit SAP130 isoform X1
106839322 SAP25; histone deacetylase complex subunit SAP25
106845858 ARID4A; AT-rich interactive domain-containing protein 4A isoform X1
106834704 ARID4B; AT-rich interactive domain-containing protein 4B isoform X2
106838804 BRMS1L; breast cancer metastasis-suppressor 1-like protein isoform X1
106833534 BRMS1; breast cancer metastasis-suppressor 1
106838210 ING1; inhibitor of growth protein 1 isoform X1
106830071 ING2; inhibitor of growth protein 2
106848691 SINHCAF; SIN3-HDAC complex-associated factor
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K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11644 SIN3A; paired amphipathic helix protein Sin3a
K10752 RBBP4; histone-binding protein RBBP4
K10752 RBBP4; histone-binding protein RBBP4
K11659 RBBP7; histone-binding protein RBBP7
K19201 SUDS3; Sin3 histone deacetylase corepressor complex component SDS3
K19202 SAP30; histone deacetylase complex subunit SAP30
K19202 SAP30; histone deacetylase complex subunit SAP30
K14324 SAP18; histone deacetylase complex subunit SAP18
K19192 SAP130; histone deacetylase complex subunit SAP130
K19193 SAP25; histone deacetylase complex subunit SAP25
K19194 ARID4A; AT-rich interactive domain-containing protein 4A
K19195 ARID4B; AT-rich interactive domain-containing protein 4B
K19196 BRMS1; breast cancer metastasis-suppressor 1 and related proteins
K19196 BRMS1; breast cancer metastasis-suppressor 1 and related proteins
K19197 ING1; inhibitor of growth protein 1
K19198 ING2; inhibitor of growth protein 2
K26090 SINHCAF; SIN3-HDAC complex-associated factor
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BRAF-HDAC complex
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106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106832313 HMG20B; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
106839994 KDM1A; LOW QUALITY PROTEIN: lysine-specific histone demethylase 1A
106839630 RCOR1; REST corepressor 1
106843988 PHF21A; PHD finger protein 21A isoform X1
106828876 ZMYM3; zinc finger MYM-type protein 3 isoform X1
106830522 ZMYM4; zinc finger MYM-type protein 4 isoform X2
106841447 ZMYM2; zinc finger MYM-type protein 2 isoform X1
106824871 ZNF217; zinc finger protein 217
106829493 GSE1; genetic suppressor element 1 isoform X1
106840983 GTF2I; general transcription factor II-I isoform X1
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K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K24650 HMG20B; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
K11829 RCOR1; REST corepressor 1
K24651 PHF21A; PHD finger protein 21A
K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4
K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4
K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4
K27275 ZNF217; zinc finger protein 217
K27276 GSE1; genetic suppressor element 1
K03121 TFII-I; transcription initiation factor TFII-I
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REST complex
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106841687 REST; RE1-silencing transcription factor
106831283 SIN3A; paired amphipathic helix protein Sin3a
106846867 SIN3B; paired amphipathic helix protein Sin3b isoform X2
106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106839630 RCOR1; REST corepressor 1
106833645 RCOR2; REST corepressor 2 isoform X1
106827147 RCOR3; REST corepressor 3 isoform X1
106839994 KDM1A; LOW QUALITY PROTEIN: lysine-specific histone demethylase 1A
106834851 SMARCA2; LOW QUALITY PROTEIN: probable global transcription activator SNF2L2
106846614 transcription activator BRG1
106822324 EHMT2; histone-lysine N-methyltransferase EHMT2 isoform X1
106822761 EHMT1; histone-lysine N-methyltransferase EHMT1 isoform X1
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K09222 REST; RE1-silencing transcription factor
K11644 SIN3A; paired amphipathic helix protein Sin3a
K23213 SIN3B; paired amphipathic helix protein Sin3b
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11829 RCOR1; REST corepressor 1
K26242 RCOR2_3; REST corepressor 2/3
K26242 RCOR2_3; REST corepressor 2/3
K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
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SHIP complex
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106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106844848 INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
106840113 HSPA2; heat shock-related 70 kDa protein 2
106822514 KCTD19; BTB/POZ domain-containing protein KCTD19 isoform X1
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K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K03084 SHIP1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K26598 HSPA2; heat shock 70kDa protein 2
K26581 KCTD19; BTB/POZ domain-containing protein KCTD19
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MiDAC complex
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106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106827679 MIDEAS; mitotic deacetylase-associated SANT domain protein isoform X1
106843026 DNTTIP1; deoxynucleotidyltransferase terminal-interacting protein 1
106824544 TRERF1; transcriptional-regulating factor 1 isoform X1
106845153 ZNF541; zinc finger protein 541
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K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K26582 MIDEAS; mitotic deacetylase-associated SANT domain protein
K08707 DNTTIP1; deoxynucleotidyltransferase terminal-interacting protein 1
K26583 TRERF1; transcriptional-regulating factor 1
K26584 ZNF541; zinc finger protein 541
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SMART complex
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Other HDAC associated proteins
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HMTs (histone methyltransferases)
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HMT complexes
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Canonical PRC1 (PRC1.2/1.4)
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Noncanonical PRC1 (PRC1.1)
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Noncanonical PRC1 (PRC1.3/1.5)
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Noncanonical PRC1 (PRC1.6)
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106834602 RING1; E3 ubiquitin-protein ligase RING1
106837005 RNF2; E3 ubiquitin-protein ligase RING2
106838249 PCGF6; polycomb group RING finger protein 6 isoform X1
106827917 RING1 and YY1-binding protein
106845847 YAF2; YY1-associated factor 2 isoform X3
106846038 E2F6; transcription factor E2F6 isoform X1
106848197 TFDP1; transcription factor Dp-1 isoform X1
106844892 MAX; protein max isoform X1
106841350 MGA; MAX gene-associated protein isoform X1
106847191 L3MBTL4; LOW QUALITY PROTEIN: lethal(3)malignant brain tumor-like protein 4
106835376 L3MBTL3; lethal(3)malignant brain tumor-like protein 3 isoform X4
106842458 L3MBTL2; lethal(3)malignant brain tumor-like protein 2 isoform X1
106823224 CBX3; chromobox protein homolog 3 isoform X1
106845344 WDR5; LOW QUALITY PROTEIN: WD repeat-containing protein 5
106823723 WDR5B; LOW QUALITY PROTEIN: WD repeat-containing protein 5B
106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
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K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
K11470 PCGF6; polycomb group RING finger protein 6
K11469 RYBP; RING1 and YY1-binding protein
K11468 YAF2; YY1-associated factor 2
K09390 E2F6; transcription factor E2F6
K04683 TFDP1; transcription factor Dp-1
K04453 MAX; Max protein
K23399 MGA; MAX gene-associated protein
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
K11586 CBX3; chromobox protein 3
K14963 WDR5; COMPASS component SWD3
K14963 WDR5; COMPASS component SWD3
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
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PRC2.1
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PRC2.2
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PR-DUB complex
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Other PRC associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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HP1 (heterochromatin protein 1)
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MBPs (metylated DNA binding proteins)
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Other heterochromatin formation proteins
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106846920 ATRX; transcriptional regulator ATRX
106841523 DNMT1; DNA (cytosine-5)-methyltransferase 1 isoform X1
106841074 DNMT3A; DNA (cytosine-5)-methyltransferase 3A isoform X1
106833740 DNMT3B; DNA (cytosine-5)-methyltransferase 3B isoform X5
106824455 DNMT3L; DNA (cytosine-5)-methyltransferase 3-like
106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106831283 SIN3A; paired amphipathic helix protein Sin3a
106844145 CHD3; chromodomain-helicase-DNA-binding protein 3 isoform X1
106847291 CHD4; chromodomain-helicase-DNA-binding protein 4 isoform X1
106829040 RBBP4; histone-binding protein RBBP4 isoform X2
106832438 LOW QUALITY PROTEIN: histone-binding protein RBBP4-like
106826721 activating transcription factor 7-interacting protein 1 isoform X1
106836761 ATF7IP2; activating transcription factor 7-interacting protein 2
106846522 SETDB1; histone-lysine N-methyltransferase SETDB1 isoform X1
106829693 SETDB2; histone-lysine N-methyltransferase SETDB2
106827436 SUV39H1; histone-lysine N-methyltransferase SUV39H1
106840452 SUV39H2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SUV39H2
106844724 LBR; delta(14)-sterol reductase LBR
106827220 SALL3; sal-like protein 3 isoform X1
106833257 SALL2; sal-like protein 2 isoform X2
106825546 SALL4; LOW QUALITY PROTEIN: sal-like protein 4
106822664 SALL1; sal-like protein 1
106829973 MPHOSPH8; M-phase phosphoprotein 8 isoform X1
106845843 PPHLN1; periphilin-1 isoform X3
106848651 TASOR; protein TASOR isoform X1
106825633 activity-dependent neuroprotector homeobox protein
106839102 AHDC1; AT-hook DNA-binding motif-containing protein 1
106848200 CHAMP1; chromosome alignment-maintaining phosphoprotein 1
106848363 POGZ; pogo transposable element with ZNF domain isoform X1
106825861 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
106827400 LRIF1; ligand-dependent nuclear receptor-interacting factor 1 isoform X1
106844548 SLFN12; schlafen family member 12
106835010 WDR76; WD repeat-containing protein 76 isoform X4
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K10779 ATRX; transcriptional regulator ATRX
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K17400 DNMT3L; DNA (cytosine-5)-methyltransferase 3-like
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11644 SIN3A; paired amphipathic helix protein Sin3a
K11642 CHD3; chromodomain-helicase-DNA-binding protein 3 [EC:5.6.2.-]
K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
K10752 RBBP4; histone-binding protein RBBP4
K10752 RBBP4; histone-binding protein RBBP4
K25802 ATF7IP; activating transcription factor 7-interacting protein
K25802 ATF7IP; activating transcription factor 7-interacting protein
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K19532 LBR; Delta14-sterol reductase (lamin-B receptor) [EC:1.3.1.70]
K19871 SALL; sal-like protein
K19871 SALL; sal-like protein
K19871 SALL; sal-like protein
K19871 SALL; sal-like protein
K21871 MPHOSPH8; M-phase phosphoprotein 8
K21872 PPHLN1; periphilin-1
K21873 FAM208A; protein TASOR
K22591 ADNP; activity-dependent neuroprotector homeobox protein
K22592 AHDC1; AT-hook DNA-binding motif-containing protein 1
K22593 CHAMP1; chromosome alignment-maintaining phosphoprotein 1
K22594 POGZ; pogo transposable element with ZNF domain
K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
K23220 LRIF1; ligand-dependent nuclear receptor-interacting factor 1
K24457 SLFN12; schlafen family member 12
K24755 WDR76; WD repeat-containing protein 76
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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BAF complex
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PBAF complex
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GBAF(ncBAF) complex
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CHRAC complex
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RSF complex
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WICH complex
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B-WICH complex
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NORC complex
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BRF complex
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NuRD complex
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106829049 HDAC1; histone deacetylase 1
106847042 HDAC2; histone deacetylase 2
106844145 CHD3; chromodomain-helicase-DNA-binding protein 3 isoform X1
106847291 CHD4; chromodomain-helicase-DNA-binding protein 4 isoform X1
106829040 RBBP4; histone-binding protein RBBP4 isoform X2
106832438 LOW QUALITY PROTEIN: histone-binding protein RBBP4-like
106845829 RBBP7; histone-binding protein RBBP7 isoform X1
106826218 MTA1; metastasis-associated protein MTA1 isoform X3
106826830 MTA2; metastasis-associated protein MTA2 isoform X1
106825973 MTA3; metastasis-associated protein MTA3 isoform X1
106834178 MBD3; methyl-CpG-binding domain protein 3 isoform X1
106825455 GATAD2A; transcriptional repressor p66-alpha isoform X2
106846254 GATAD2B; transcriptional repressor p66-beta isoform X5
106823573 PHF6; PHD finger protein 6 isoform X1
106842330 CDK2AP1; cyclin-dependent kinase 2-associated protein 1 isoform X1
106833488 CDK2AP2; cyclin-dependent kinase 2-associated protein 2 isoform X1
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K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11642 CHD3; chromodomain-helicase-DNA-binding protein 3 [EC:5.6.2.-]
K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
K10752 RBBP4; histone-binding protein RBBP4
K10752 RBBP4; histone-binding protein RBBP4
K11659 RBBP7; histone-binding protein RBBP7
K11660 MTA; metastasis-associated protein MTA
K11660 MTA; metastasis-associated protein MTA
K11660 MTA; metastasis-associated protein MTA
K11591 MBD3; methyl-CpG-binding domain protein 3
K23194 GATAD2; transcriptional repressor p66
K23194 GATAD2; transcriptional repressor p66
K23310 PHF6; PHD finger protein 6
K26454 CDK2AP1; cyclin-dependent kinase 2-associated protein 1
K26455 CDK2AP2; cyclin-dependent kinase 2-associated protein 2
|
NuRF complex
|
NuRF complex (fruit fly)
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CERF complex
|
SRCAP complex
|
INO80 complex
|
INO80 complex (yeast)
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RSC complex
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SWI/SNF complex
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SWR1 complex
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ASTRA complex
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Other chromatin remodeling factors
|
|
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Prokaryotic type
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