 Common components
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 Complex A
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U1 snRNP components
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Sm proteins
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U1 snRNP specific factors
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U1 related factors
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 K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
K12821 PRPF40, PRP40; pre-mRNA-processing factor 40
K12822 RBM25, S164; RNA-binding protein 25
K12824 TCERG1, CA150; transcription elongation regulator 1
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U2 snRNP components
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Sm proteins
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U2 snRNP specific factors
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U2 related factors
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K12836 U2AF1; splicing factor U2AF 35 kDa subunit
K12837 U2AF2; splicing factor U2AF 65 kDa subunit
K12841 CHERP; calcium homeostasis endoplasmic reticulum protein
K12820 DHX15, PRP43; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:5.6.2.6]
K12811 DDX46, PRP5; ATP-dependent RNA helicase DDX46/PRP5 [EC:5.6.2.7]
K12838 PUF60; poly(U)-binding-splicing factor PUF60
K12840 RBM17, SPF45; splicing factor 45
K12839 SMNDC1, SPF30; survival of motor neuron-related-splicing factor 30
K12842 SR140; U2-associated protein SR140
K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
K24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein
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Other components
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Complex B
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U1 snRNP components
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Sm proteins
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U1 snRNP specific factors
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U1 related factors
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K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
K12821 PRPF40, PRP40; pre-mRNA-processing factor 40
K12822 RBM25, S164; RNA-binding protein 25
K12824 TCERG1, CA150; transcription elongation regulator 1
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U2 snRNP components
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Sm proteins
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U2 snRNP specific factors
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U2 related factors
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K12836 U2AF1; splicing factor U2AF 35 kDa subunit
K12837 U2AF2; splicing factor U2AF 65 kDa subunit
K12841 CHERP; calcium homeostasis endoplasmic reticulum protein
K12820 DHX15, PRP43; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:5.6.2.6]
K12811 DDX46, PRP5; ATP-dependent RNA helicase DDX46/PRP5 [EC:5.6.2.7]
K12838 PUF60; poly(U)-binding-splicing factor PUF60
K12840 RBM17, SPF45; splicing factor 45
K12839 SMNDC1, SPF30; survival of motor neuron-related-splicing factor 30
K12842 SR140; U2-associated protein SR140
K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
K24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein
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U4/U6.U5 tri-snRNP components
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Sm proteins
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LSm proteins
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U4/U6 snRNP specific factors
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U5 snRNP specific factors
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U4/U6.U5 tri-snRNP specific factors
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U4/U6.U5 tri-snRNP related factors
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K12848 SNU23; U4/U6.U5 tri-snRNP component SNU23
K12849 PRPF38A; pre-mRNA-splicing factor 38A
K12850 PRPF38B; pre-mRNA-splicing factor 38B
K12851 PRP38; pre-mRNA-splicing factor 38
K13100 CWC22; pre-mRNA-splicing factor CWC22
K12598 MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
K12813 DHX16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:5.6.2.6]
K12814 PRP2; pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2 [EC:5.6.2.6]
K13101 GPKOW; G patch domain and KOW motifs-containing protein
K28512 SPP2; pre-mRNA-splicing factor SPP2
K04455 HSPB1; heat shock protein beta-1
K10598 PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
K13104 ZNF830, CCDC16; zinc finger protein 830
K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
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Other components
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Prp19 complex
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Prp19-related factors
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K06063 SNW1, SKIIP, SKIP; SNW domain-containing protein 1
K12867 SYF1, XAB2; pre-mRNA-splicing factor SYF1
K12868 SYF2; pre-mRNA-splicing factor SYF2
K12869 CRN, CRNKL1, CLF1, SYF3; crooked neck
K12874 AQR; intron-binding protein aquarius
K12873 BUD31, G10; bud site selection protein 31
K12871 CCDC12; coiled-coil domain-containing protein 12
K12870 ISY1; pre-mRNA-splicing factor ISY1
K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
K13105 PRCC; proline-rich protein PRCC
K12872 RBM22, SLT11; pre-mRNA-splicing factor RBM22/SLT11
K25780 KHDC4, BLOM7; kelch domain-containing protein 4
K27398 CWC2; pre-mRNA-splicing factor CWC2
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RES complex
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Complex B specific factors
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Complex C
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U2 snRNP components
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U4/U6.U5 tri-snRNP components
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Sm proteins
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U5 SnRNP specific factors
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U4/U6.U5 tri-SnRNP related factors
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K13100 CWC22; pre-mRNA-splicing factor CWC22
K12598 MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
K12820 DHX15, PRP43; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:5.6.2.6]
K04455 HSPB1; heat shock protein beta-1
K10598 PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
K13104 ZNF830, CCDC16; zinc finger protein 830
K13103 TFIP11; tuftelin-interacting protein 11
K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
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Other components
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Prp19-CDC5 complex
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Prp19-related factors
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K06063 SNW1, SKIIP, SKIP; SNW domain-containing protein 1
K12867 SYF1, XAB2; pre-mRNA-splicing factor SYF1
K12868 SYF2; pre-mRNA-splicing factor SYF2
K12869 CRN, CRNKL1, CLF1, SYF3; crooked neck
K12874 AQR; intron-binding protein aquarius
K12873 BUD31, G10; bud site selection protein 31
K12871 CCDC12; coiled-coil domain-containing protein 12
K12870 ISY1; pre-mRNA-splicing factor ISY1
K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
K12872 RBM22, SLT11; pre-mRNA-splicing factor RBM22/SLT11
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RES complex
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EJC/TREX
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Step II factors
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PPlases
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hnRNP proteins
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Complex C specific factors
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Other splicing related proteins
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Proteins involved in snRNP biogenesis
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SMN complex factors
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Integrator complex
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Other proteins involved in snRNP biogenesis
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K13150 COIL, CLN80; coilin
K12839 SMNDC1, SPF30; survival of motor neuron-related-splicing factor 30
K13151 SNUPN, RNUT1; snurportin-1
K23093 USB1; U6 snRNA phosphodiesterase [EC:3.1.4.-]
K28400 THUMPD2; U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 [EC:2.1.1.-]
K15448 TRM112, TRMT112; multifunctional methyltransferase subunit TRM112
K05019 CLNS1A; chloride channel, nucleotide-sensitive, 1A
K14292 TGS1; trimethylguanosine synthase [EC:2.1.1.-]
K13180 INTS6L, DDX26B; integrator complex subunit 6-like
K06874 ZPR1; zinc finger protein ZPR1
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Minor spliceosome components
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Spliceosome associated proteins (SAPs)
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hnRNP proteins
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SR proteins
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K12899 SRSF11, SFRS11; serine/arginine-rich splicing factor 11
K13165 SREK1, SFRS12; splicing regulatory glutamine/lysine-rich protein 1
K13166 SUGP2, SFRS14; SURP and G-patch domain-containing protein 2
K13167 SCAF4, SFRS15; SR-related and CTD-associated factor 4
K13168 CLASRP, SFRS16; CLK4-associating serine/arginine rich protein
K13169 AKAP17, SFRS17; A-kinase anchor protein 17
K13170 PNISR, SFRS18; arginine/serine-rich protein PNISR
K25101 SRSF12; serine/arginine-rich splicing factor 12
K28949 ARL6IP4; ADP-ribosylation factor-like protein 6-interacting protein 4
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SR-related proteins
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K13171 SRRM1, SRM160; serine/arginine repetitive matrix protein 1
K13172 SRRM2, SRM300; serine/arginine repetitive matrix protein 2
K13173 ARGLU1; arginine and glutamate-rich protein 1
K23718 SON; protein SON
K25057 PSIP1, LEDGF; PC4 and SFRS1-interacting protein
K25781 ILDR1; immunoglobulin-like domain-containing receptor 1
K25782 ILDR2; immunoglobulin-like domain-containing receptor 2
K26076 ZRANB2; zinc finger Ran-binding domain-containing protein 2
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TREX complex
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RNA helicase-like proteins
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RNA binding proteins (RBPs)
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Other SAPs
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Splicing related RNAs
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K14276 U1snRNA; U1 spliceosomal RNA
K14277 U2snRNA; U2 spliceosomal RNA
K14278 U4snRNA; U4 spliceosomal RNA
K14279 U5snRNA; U5 spliceosomal RNA
K14280 U6snRNA; U6 spliceosomal RNA
K28308 RNU7; U7 small nuclear RNA
K28309 RNU11; U11 small nuclear RNA
K28310 RNU12; U12 small nuclear RNA
K26388 RNU4ATAC; U4atac small nuclear RNA
K26387 RNU6ATAC; U6atac small nuclear RNA
K27200 SNORD7; small nucleolar RNA SNORD7
K27201 SNORD8_9; small nucleolar RNA SNORD8/9
K27206 SNORD10; small nucleolar RNA SNORD10
K26386 SNORD115; small nucleolar RNA SNORD115
K27152 SCARNA1, ACA35; small Cajal body-specific RNA 1
K27161 SCARNA2; small Cajal body-specific RNA 2
K28401 SCARNA3; small Cajal body-specific RNA 3
K27153 SCARNA4, ACA26; small Cajal body-specific RNA 4
K27154 SCARNA6, SCARNA5; small Cajal body-specific RNA 6
K27166 SCARNA7, U90; small Cajal body-specific RNA 7
K27167 SCARNA8, U92; small Cajal body-specific RNA 8
K27168 SCARNA9; small Cajal body-specific RNA 9
K27155 SCARNA10, U85; small Cajal body-specific RNA 10
K27156 SCARNA11, ACA57; small Cajal body-specific RNA 11
K27157 SCARNA12, U89; small Cajal body-specific RNA 12
K27169 SCARNA13, U93; small Cajal body-specific RNA 13
K27170 SCARNA14, U100; small Cajal body-specific RNA 14
K27158 SCARNA15, ACA45; small Cajal body-specific RNA 15
K27159 SCARNA16, ACA47; small Cajal body-specific RNA 16
K27171 SCARNA17, U91; small Cajal body-specific RNA 17
K27172 SCARNA18, U109; small Cajal body-specific RNA 18
K28311 SCARNA20, ACA66; small Cajal body-specific RNA 20
K28312 SCARNA21, ACA68; small Cajal body-specific RNA 21
K28313 SCARNA23, SCARNA22; small Cajal body-specific RNA 23
K27160 SCARNA24, SCARNA23; small Cajal body-specific RNA 24
K28451 SCARNA28, ZL1; small Cajal body-specific RNA 28
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Spliceosome