KEGG    Network variation - Prostate cancer
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ENTRYnt06272
NameProstate cancer
CategoryDisease view; Cancer
Pathwayhsa05215 Prostate cancer
DiseaseH00024 Prostate cancer
Display drug-target relation   disease type
PI3K signaling
N00220    PTENPIP3AKT
N00052    PTEN*PIP3AKT
N00082      NKX3-1*AKTBAD
 
Nuclear receptor signaling
   D1,D2,D3,D4,D5,D6
 |
  
N00083    (T,DHT)ARKLK3
N00085    (T,DHT,E2,P4,FLUT,..AR*KLK3
N00084    (T,DHT)AR*KLK3
 
Cell cycle
N00091    (SCF+SKP2)CDKN1B((CCNA,CCNE)+CDK2)RB1E2F
N00093      CDKN1B*(CCNE+CDK2)RB1E2F
 
Transcription
N00128    TMPRSS2-ERG(PLAU,PLAT,MMP3,MM..
N00129    TMPRSS2-ERGSPINT1
N00130    TMPRSS2-ETV5(PLAU,MMP9)


Drug name
D1D00586Flutamide (JP18/USP/INN)
D2D00961Bicalutamide (JP18/USP/INN)
D3D00965Nilutamide (USAN/INN)
D4D10218Enzalutamide (JAN/USAN)
D5D11040Apalutamide (JAN/INN)
D6D11045Darolutamide (JAN/USAN/INN)