KEGG   ORTHOLOGY: K04362
Entry
K04362                      KO                                     

Name
FGFR1, CD331
Definition
fibroblast growth factor receptor 1 [EC:2.7.10.1]
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04520  Adherens junction
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04714  Thermogenesis
ko04810  Regulation of actin cytoskeleton
ko04928  Parathyroid hormone synthesis, secretion and action
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05215  Prostate cancer
ko05218  Melanoma
ko05224  Breast cancer
ko05230  Central carbon metabolism in cancer
Disease
H00031  Breast cancer
H00255  Hypogonadotropic hypogonadism
H00443  Osteoglophonic dysplasia
H00458  Syndromic craniosynostoses
H01207  Trigonocephaly
H01756  Pfeiffer syndrome
H01850  Hartsfield syndrome
H01988  Jackson-Weiss syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04014 Ras signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04015 Rap1 signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04151 PI3K-Akt signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04550 Signaling pathways regulating pluripotency of stem cells
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05205 Proteoglycans in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05230 Central carbon metabolism in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09162 Cancer: specific types
   05218 Melanoma
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05215 Prostate cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05224 Breast cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   00536 Glycosaminoglycan binding proteins
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
CD molecules [BR:ko04090]
 Proteins
  K04362  CD331, FGFR1; fibroblast growth factor receptor 1
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Growth factors/receptors
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Other DBs
GO: 0005007
Genes
HSA: 2260(FGFR1)
PTR: 464122(FGFR1)
PPS: 100988115(FGFR1)
GGO: 101152179(FGFR1)
PON: 100174545(FGFR1)
NLE: 100602423(FGFR1)
MCC: 700126(FGFR1)
MCF: 102144714(FGFR1)
CSAB: 103215648(FGFR1)
RRO: 104679640(FGFR1)
RBB: 108512401(FGFR1)
CJC: 100390192(FGFR1)
SBQ: 101033213(FGFR1)
MMU: 14182(Fgfr1)
MCAL: 110299550(Fgfr1)
MPAH: 110336809(Fgfr1)
RNO: 79114(Fgfr1)
MUN: 110563307(Fgfr1)
CGE: 100773586(Fgfr1)
NGI: 103745770(Fgfr1)
HGL: 101700324(Fgfr1)
CCAN: 109688936(Fgfr1)
OCU: 100351861(FGFR1)
TUP: 102484087(FGFR1)
CFA: 100856477(FGFR1)
VVP: 112916136(FGFR1)
AML: 100472630(FGFR1)
UMR: 103659146(FGFR1)
UAH: 113262086(FGFR1)
ORO: 101364849(FGFR1)
ELK: 111144420
FCA: 101086055(FGFR1)
PTG: 102972346(FGFR1)
PPAD: 109262303(FGFR1)
AJU: 106978376(FGFR1)
BTA: 281768(FGFR1)
BOM: 102267776(FGFR1)
BIU: 109553304(FGFR1)
BBUB: 102407288(FGFR1)
CHX: 102180282(FGFR1)
OAS: 780507(FGFR1)
SSC: 100153248(FGFR1)
CFR: 102515264(FGFR1)
CDK: 105105270(FGFR1)
BACU: 103017733(FGFR1)
LVE: 103069902(FGFR1)
OOR: 101279623(FGFR1)
DLE: 111173523(FGFR1)
PCAD: 102989551(FGFR1)
ECB: 100057614(FGFR1)
EPZ: 103560266(FGFR1)
EAI: 106824659(FGFR1)
MYB: 102253832(FGFR1)
MYD: 102759202(FGFR1)
MNA: 107535065(FGFR1)
HAI: 109373149(FGFR1)
DRO: 112306733(FGFR1)
PALE: 102898943(FGFR1)
RAY: 107515961(FGFR1)
MJV: 108403050(FGFR1)
LAV: 100662289(FGFR1)
TMU: 101342270
MDO: 100029852(FGFR1)
SHR: 100914347(FGFR1)
PCW: 110207578(FGFR1)
OAA: 100074240(FGFR1)
GGA: 396516(FGFR1)
MGP: 100547498(FGFR1)
CJO: 107323773(FGFR1)
NMEL: 110387131(FGFR1)
ACYG: 106044374(FGFR1)
TGU: 100221243(FGFR1)
LSR: 110473397(FGFR1)
SCAN: 103822693(FGFR1)
GFR: 102033908(FGFR1)
FAB: 101822220(FGFR1)
PHI: 102103637(FGFR1)
PMAJ: 107213845(FGFR1)
CCAE: 111938850(FGFR1)
CCW: 104694904(FGFR1)
ETL: 114066493(FGFR1)
FPG: 101914093(FGFR1)
FCH: 102055369(FGFR1)
CLV: 102085235(FGFR1)
EGZ: 104135322(FGFR1)
NNI: 104016019(FGFR1)
PADL: 103912362(FGFR1)
AAM: 106492992(FGFR1)
ASN: 102386174(FGFR1)
AMJ: 102574117(FGFR1)
PSS: 102461506(FGFR1)
CMY: 102942878
CPIC: 101941076(FGFR1)
ACS: 100559018(fgfr1)
PVT: 110072166(FGFR1)
PBI: 103066603(FGFR1)
PMUR: 107289991(FGFR1)
TSR: 106545617(FGFR1)
PMUA: 114585343(FGFR1)
GJA: 107113006(FGFR1)
XLA: 394418(fgfr1.L) 397782(xfgfra2) 399444(fgfr1.S)
XTR: 548648(fgfr1)
NPR: 108791453(FGFR1)
DRE: 30705(fgfr1a) 567905(fgfr1b) 569566
EEE: 113588173
TRU: 101073964 101078564(fgfr1)
OLA: 100125448(fgfr1) 101155126
XCO: 114149547 114154182(fgfr1)
CVG: 107081801
AOCE: 111571065
MALB: 109954836
LCM: 102361014(FGFR1)
CMK: 103190693
CIN: 101242971 445706(fgfr)
SPU: 373310(FGFR)
DME: Dmel_CG10244(Cad96Ca)
DER: 6555476
DSE: 6619674
DSI: Dsimw501_GD18227(Dsim_GD18227)
DAN: 6499881
DSR: 110189031
DPE: 6591372
DMN: 108156267
DWI: 6651312
DAZ: 108621257
DNV: 108650218
DHE: 111601307
DVI: 6629492
MDE: 101899591
LCQ: 111681381
AAG: 5566872
AME: 409061
BIM: 100741569
BTER: 100645261
CCAL: 108630549
OBB: 114878584
SOC: 105196016
MPHA: 105830817
AEC: 105151199
ACEP: 105624990
DQU: 106748875
LHU: 105675703
PGC: 109853575
OBO: 105287184
PCF: 106787566
CSOL: 105368181
MDL: 103574949
TCA: 659961(Cad96Ca)
DPA: 109536590
ATD: 109595758
NVL: 108565944
BMOR: 101745512
BMAN: 114253316
PMAC: 106720097
PRAP: 111004172
HAW: 110379194
TNL: 113500453
PXY: 105387388
DNX: 107166442
AGS: 114124499
RMD: 113556718
BTAB: 109043826
CLEC: 106674164
ZNE: 110836649
PVM: 113825602
TUT: 107365937
DPTE: 113790798
CSCU: 111629419
PTEP: 107441235
CBR: CBG04906
TSP: Tsp_00617
CRG: 105321229
MYI: 110459294
EGL: EGR_04208
AQU: 100632318
 » show all
Reference
PMID:1697263
  Authors
Dionne CA, Crumley G, Bellot F, Kaplow JM, Searfoss G, Ruta M, Burgess WH, Jaye M, Schlessinger J
  Title
Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.
  Journal
EMBO J 9:2685-92 (1990)
DOI:10.1002/j.1460-2075.1990.tb07454.x
  Sequence
[hsa:2260]
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