KEGG   ORTHOLOGY: K11220
Entry
K11220                      KO                                     
Symbol
STAT1
Name
signal transducer and activator of transcription 1
Pathway
map04062  Chemokine signaling pathway
map04217  Necroptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map05140  Leishmaniasis
map05145  Toxoplasmosis
map05152  Tuberculosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05164  Influenza A
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05212  Pancreatic cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
H01109  Chronic mucocutaneous candidiasis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11220  STAT1; signal transducer and activator of transcription 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04621 NOD-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04625 C-type lectin receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04658 Th1 and Th2 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04659 Th17 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04062 Chemokine signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04935 Growth hormone synthesis, secretion and action
    K11220  STAT1; signal transducer and activator of transcription 1
   04919 Thyroid hormone signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11220  STAT1; signal transducer and activator of transcription 1
   05160 Hepatitis C
    K11220  STAT1; signal transducer and activator of transcription 1
   05171 Coronavirus disease - COVID-19
    K11220  STAT1; signal transducer and activator of transcription 1
   05164 Influenza A
    K11220  STAT1; signal transducer and activator of transcription 1
   05162 Measles
    K11220  STAT1; signal transducer and activator of transcription 1
   05168 Herpes simplex virus 1 infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05169 Epstein-Barr virus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05165 Human papillomavirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K11220  STAT1; signal transducer and activator of transcription 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05140 Leishmaniasis
    K11220  STAT1; signal transducer and activator of transcription 1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K11220  STAT1; signal transducer and activator of transcription 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11220  STAT1; signal transducer and activator of transcription 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11220  STAT1; signal transducer and activator of transcription 1
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11220  STAT1; signal transducer and activator of transcription 1
Genes
HSA: 6772(STAT1)
PTR: 459834(STAT1)
PPS: 100971620(STAT1)
GGO: 101131770(STAT1)
PON: 100173683(STAT1)
NLE: 100596344(STAT1)
HMH: 116810529(STAT1)
MCC: 693650(STAT1)
MCF: 101925134(STAT1)
MTHB: 126932637
MNI: 105468204(STAT1)
CSAB: 103217529(STAT1)
CATY: 105579958(STAT1)
PANU: 101005886(STAT1)
TGE: 112635950(STAT1)
MLEU: 105535217(STAT1)
RRO: 104675282(STAT1)
RBB: 108527866(STAT1)
TFN: 117094713(STAT1)
PTEH: 111546340(STAT1)
CANG: 105507777(STAT1)
CJC: 100401630(STAT1)
SBQ: 101030811(STAT1)
CIMI: 108284049(STAT1)
CSYR: 103256404(STAT1)
MMUR: 105877906(STAT1)
LCAT: 123643619(STAT1)
PCOQ: 105813290(STAT1)
OGA: 100956762(STAT1)
MMU: 20846(Stat1)
MCAL: 110304843(Stat1)
MPAH: 110321139(Stat1)
RNO: 25124(Stat1)
MCOC: 116088407(Stat1)
ANU: 117705244(Stat1)
MUN: 110552020(Stat1)
CGE: 100755609(Stat1)
MAUA: 101827798(Stat1)
PROB: 127226208(Stat1)
PLEU: 114705035(Stat1)
MFOT: 126511873
AAMP: 119803912(Stat1)
NGI: 103736156(Stat1)
HGL: 101718902(Stat1)
CPOC: 100724708(Stat1)
CCAN: 109679865 109682738(Stat1)
DORD: 105995197(Stat1)
DSP: 122115055(Stat1)
PLOP: 125350458(Stat1)
NCAR: 124979200
MMMA: 107138551(Stat1)
OPI: 101525476(STAT1)
TUP: 102476590(STAT1)
GVR: 103588074(STAT1)
CFA: 488449(STAT1)
CLUD: 112656324(STAT1)
VVP: 112922923(STAT1)
VLG: 121480638(STAT1)
NPO: 129522804(STAT1)
AML: 100474026(STAT1)
UMR: 103659933(STAT1)
UAH: 113250654(STAT1)
UAR: 123798145(STAT1)
ELK: 111144592
LLV: 125095018
MPUF: 101686596(STAT1)
MNP: 132013398(STAT1)
MLK: 131827656(STAT1)
NVS: 122902129(STAT1)
ORO: 101378785(STAT1)
EJU: 114223921(STAT1)
ZCA: 113919574(STAT1)
MLX: 118012204(STAT1)
NSU: 110592138(STAT1)
LWW: 102731818(STAT1)
FCA: 101084561(STAT1)
PYU: 121030838(STAT1)
PCOO: 112869860(STAT1)
PBG: 122481579(STAT1)
PVIV: 125173414(STAT1)
LRUF: 124515343
PTG: 102953174(STAT1)
PPAD: 109274693(STAT1)
PUC: 125911435
AJU: 106979712
HHV: 120233455(STAT1)
BTA: 510814(STAT1)
BOM: 102283508(STAT1)
BIU: 109568771(STAT1)
BBUB: 102415500(STAT1)
BBIS: 105003595(STAT1)
CHX: 102189170(STAT1)
OAS: 100307049(STAT1)
BTAX: 128071221(STAT1)
ODA: 120854684(STAT1)
CCAD: 122426277(STAT1)
MBEZ: 129537915(STAT1)
SSC: 396655(STAT1)
CFR: 102509999(STAT1)
CBAI: 105063982(STAT1)
CDK: 105088783(STAT1)
VPC: 102544679(STAT1)
BACU: 103013781
BMUS: 118898022(STAT1)
LVE: 103069117
OOR: 101272458(STAT1)
DLE: 111171663(STAT1)
PCAD: 102977655(STAT1)
PSIU: 116757187(STAT1)
NASI: 112392137(STAT1)
ECB: 100069633(STAT1)
EPZ: 103548655(STAT1)
EAI: 106828796(STAT1)
MYB: 102243651(STAT1)
MYD: 102757059(STAT1)
MMYO: 118661220(STAT1)
MLF: 102424662(STAT1)
PKL: 118709492(STAT1)
EFUS: 103290572(STAT1)
MNA: 107540521(STAT1)
DRO: 112307780(STAT1)
SHON: 118985299(STAT1)
AJM: 119062093(STAT1)
PDIC: 114494120(STAT1)
PHAS: 123816523(STAT1)
MMF: 118625659(STAT1)
PPAM: 129065467(STAT1)
HAI: 109393276(STAT1)
RFQ: 117025725(STAT1)
PALE: 102886603(STAT1)
PGIG: 120587473(STAT1)
PVP: 105289309(STAT1)
RAY: 107519182(STAT1)
MJV: 108400080(STAT1)
TOD: 119256041(STAT1)
SARA: 101554357(STAT1)
LAV: 100668424(STAT1)
TMU: 101357916
ETF: 101650838(STAT1)
DNM: 101436399(STAT1)
MDO: 100028917(STAT1)
GAS: 123242151(STAT1)
SHR: 105749862(STAT1)
AFZ: 127554459
PCW: 110213248(STAT1)
OAA: 100087266(STAT1)
GGA: 424044(STAT1)
PCOC: 116235961(STAT1)
MGP: 100544816(STAT1)
CJO: 107316322(STAT1)
TPAI: 128077102(STAT1)
LMUT: 125697226(STAT1)
NMEL: 110399457(STAT1)
APLA: 101795022(STAT1)
ACYG: 106039967(STAT1)
CATA: 118261546(STAT1)
AFUL: 116490500(STAT1)
TGU: 100221342(STAT1)
LSR: 110471109(STAT1)
SCAN: 103814539(STAT1)
PMOA: 120511477(STAT1)
OTC: 121335389(STAT1)
PRUF: 121364380(STAT1)
GFR: 102036007(STAT1)
FAB: 101811260(STAT1)
OMA: 130255273(STAT1)
PHI: 102100816(STAT1)
PMAJ: 107207405(STAT1)
CCAE: 111931930(STAT1)
CCW: 104693738(STAT1)
CBRC: 103612443(STAT1)
ETL: 114057449(STAT1)
ZAB: 102075199(STAT1)
ACHL: 103800628(STAT1)
SVG: 106855910(STAT1)
MMEA: 130578196(STAT1)
HRT: 120755497(STAT1)
FPG: 101922205(STAT1)
FCH: 102054689(STAT1)
CLV: 102098106(STAT1)
EGZ: 104130544(STAT1)
NNI: 104014274(STAT1)
PCRI: 104024447(STAT1)
PLET: 104619945(STAT1)
EHS: 104508311(STAT1)
PCAO: 104041888(STAT1)
ACUN: 113482458(STAT1)
TALA: 104362790(STAT1)
PADL: 103925472(STAT1)
AFOR: 103897147(STAT1)
ACHC: 115342511(STAT1)
HALD: 104324347(STAT1)
HLE: 104829588(STAT1)
AGEN: 126042725
GCL: 127018115
CCRI: 104167043(STAT1)
CSTI: 104560273(STAT1)
CMAC: 104485862(STAT1)
MUI: 104544870
BREG: 104643105(STAT1)
FGA: 104077124(STAT1)
GSTE: 104259693(STAT1)
LDI: 104351582(STAT1)
OHA: 104328394(STAT1)
NNT: 104413420(STAT1)
SHAB: 115608872(STAT1)
DPUB: 104309847(STAT1)
PGUU: 104457917(STAT1)
ACAR: 104525996(STAT1)
CPEA: 104386613(STAT1)
CVF: 104290959(STAT1)
RTD: 128913182(STAT1)
CUCA: 104058327(STAT1)
TEO: 104381035(STAT1)
BRHI: 104491544(STAT1)
AAM: 106492439(STAT1)
AROW: 112978333(STAT1)
NPD: 112954430(STAT1)
TGT: 104565536(STAT1)
DNE: 112982588(STAT1)
SCAM: 104143404(STAT1)
ASN: 102374439(STAT1)
AMJ: 102571738(STAT1)
CPOO: 109323031(STAT1)
GGN: 109301851(STAT1)
PSS: 102462741(STAT1)
CMY: 102934663(STAT1)
CCAY: 125644935(STAT1)
DCC: 119863823(STAT1)
CPIC: 101931440(STAT1)
TST: 117884619(STAT1)
CABI: 116815204(STAT1)
MRV: 120374631(STAT1)
ACS: 100558595(stat1)
ASAO: 132778013(STAT1)
PVT: 110083952(STAT1)
SUND: 121935257(STAT1)
PBI: 103060112(STAT1)
PMUR: 107289220(STAT1)
CTIG: 120298332(STAT1)
TSR: 106537889(STAT1)
PGUT: 117672712(STAT1)
APRI: 131201014(STAT1)
PTEX: 113433994(STAT1)
NSS: 113412400(STAT1)
VKO: 123021819(STAT1)
PMUA: 114607449(STAT1)
PRAF: 128399344(STAT1)
ZVI: 118095191(STAT1)
HCG: 128335373(STAT1)
EMC: 129323801(STAT1)
XLA: 108703082(stat1.S) 398324(stat1.L)
XTR: 780397(stat1)
NPR: 108798858(STAT1)
RTEM: 120943691(STAT1)
BBUF: 121008988(STAT1)
BGAR: 122945284(STAT1)
MUO: 115473779(STAT1)
GSH: 117360731(STAT1)
DRE: 30768(stat1a) 368481(stat1b)
PTET: 122327842(stat1a) 122351700(stat1b)
LROH: 127153806(stat1a) 127170576(stat1b) 127170859
OMC: 131531449(stat1a)
PPRM: 120477609 120477802(stat1b) 120486276(stat1a)
RKG: 130072558(stat1b) 130072594 130100395(stat1a)
MAMB: 125254061(stat1a) 125270612(stat1b)
TROS: 130549106(stat1a) 130555682(stat1b)
TDW: 130427429(stat1b) 130430030(stat1a)
MANU: 129452652 129454249(stat1a)
IPU: 108259490(stat1a) 108266311(stat1b)
IFU: 128602760(stat1a) 128608451(stat1b)
TFD: 113651885(stat1a) 113657095(stat1b) 113661254 113661265
TVC: 132838889(stat1a) 132850464 132850466(stat1b)
CMAO: 118801704(stat1a) 118809414 118821121(stat1b)
EEE: 113581352(stat1) 113586831
TRU: 101068828(stat1) 101079646
TFS: 130522341(stat1a) 130523302
NCC: 104949635
TBEN: 117469171 117485957(stat1b) 117499191(stat1a)
PGEO: 117441669(stat1a) 117466574
GACU: 117549497 117549793(stat1a)
EMAC: 134861047(stat1a) 134867158
ELY: 117249488 117250238(stat1a)
EFO: 125884694(stat1a) 125899274
SLUC: 116043142(stat1b) 116053691(stat1a)
ECRA: 117939468(stat1a) 117953178
ESP: 116674022(stat1) 116698329
GAT: 120826627(stat1a) 120834093
PPUG: 119220035(stat1a)
AFB: 129104815 129111532(stat1a)
CLUM: 117741800(stat1a)
SCHU: 122871839(stat1a) 122885811
CUD: 121506226(stat1a) 121522933
ALAT: 119015223(stat1a) 119025600
MZE: 101476764(stat1) 101486905
ONL: 100696359(stat1) 100709564
OAU: 116309467 116317095(stat1a)
OML: 112154777 112156680(stat1a)
CSAI: 133425311(stat1a)
PRET: 103457785(stat1) 103460709
PFOR: 103130104(stat1) 103130271
PLAI: 106942383(stat1) 106951655
PMEI: 106907676 106909973(stat1)
GAF: 122827058(stat1a) 122840006
PPRL: 129356612(stat1a)
CVG: 107080778 107092284(stat1)
CTUL: 119792770
GMU: 124861925(stat1a) 124870924
NFU: 107384662(stat1) 107397172
KMR: 108229342(stat1a) 108250770
ALIM: 106531438(stat1)
NWH: 119419796 119428888(stat1a)
MCEP: 125000988(stat1a) 125017356
CSEM: 103389515(stat1) 103392403
SSEN: 122758564 122763091(stat1a)
HHIP: 117754943 117774286(stat1a)
SDU: 111218101 111222701(stat1)
XGL: 120798154(stat1a) 120801616
HCQ: 109517578 109520194(stat1)
SSCV: 125988268
SBIA: 133505793(stat1a)
PEE: 133402577(stat1a)
PTAO: 133478909(stat1a)
MALB: 109955685(stat1)
BSPL: 114845713(stat1a) 114846801
SJO: 128354436(stat1a) 128367733
SASA: 100136558(STAT1) 106586142
OMY: 100136755(stat1-1) 100137016(stat1-2) 110501544(stat1b) 110520020 110527523
PKI: 111842948 111845415(stat1)
LOC: 102685821(stat1)
PSEX: 120522445
LCM: 102353760(STAT1)
CMK: 103176541
RTP: 109920367
PMRN: 116938726(STAT1)
LRJ: 133345932(STAT1)
 » show all
Reference
PMID:1502203
  Authors
Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE Jr
  Title
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
  Journal
Proc Natl Acad Sci U S A 89:7836-9 (1992)
DOI:10.1073/pnas.89.16.7836
  Sequence
[hsa:6772]
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