KEGG   COMPOUND: C00322
Entry
C00322                      Compound                               
Name
2-Oxoadipate;
2-Oxoadipic acid;
2-Oxohexanedioic acid
Formula
C6H8O5
Exact mass
160.0372
Mol weight
160.12
Structure
Reaction
R01932 R01933 R01934 R01936 R01937 R01938 R01939 R01940
R08331 R13011 R13166
Pathway
map00300  Lysine biosynthesis
map00310  Lysine degradation
map00380  Tryptophan metabolism
map00680  Methane metabolism
map00785  Lipoic acid metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00433  Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
M00960  Lysine degradation, bacteria, L-lysine => D-lysine => succinate
Network
nt06032  Lipoic acid metabolism
nt06036  Lysine degradation
Enzyme
1.1.1.87        1.1.1.172       1.1.1.286       1.2.1.-         
1.2.4.-         1.5.1.-         1.13.11.93      2.3.3.-         
2.6.1.39
Brite
Compounds with biological roles [BR:br08001]
 Organic acids
  Carboxylic acids
   2-Oxocarboxylic acids
    C00322  2-Oxoadipate
Lipids [BR:br08002]
 FA  Fatty acyls
  FA01 Fatty Acids and Conjugates
   FA0117 Dicarboxylic acids
    C00322  2-Oxohexanedioic acid
Other DBs
CAS: 3184-35-8
PubChem: 3616
ChEBI: 15753
LIPIDMAPS: LMFA01170121
KNApSAcK: C00000770
PDB-CCD: OOG[PDBj]
NIKKAJI: J39.063A
LinkDB
KCF data

ATOM        11
            1   C1b C    22.7740  -15.8016
            2   C5a C    23.9839  -16.5030
            3   C1b C    21.5577  -16.5030
            4   C6a C    25.1939  -15.8016
            5   O5a O    23.9839  -17.8995
            6   C1b C    20.3478  -15.8016
            7   O6a O    26.4038  -16.5030
            8   O6a O    25.1873  -14.5387
            9   C6a C    19.1315  -16.5030
            10  O6a O    17.9216  -15.7951
            11  O6a O    19.1380  -17.8995
BOND        10
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     4   8 2
            8     6   9 1
            9     9  10 1
            10    9  11 2

» Japanese version

KEGG   COMPOUND: C15972
Entry
C15972                      Compound                               
Name
Enzyme N6-(lipoyl)lysine;
Lipoamide-E;
[E2 protein]-N6-lipoyl-L-lysine;
[Lipoyl-carrier protein E2]-N6-lipoyl-L-lysine
Formula
C8H14NOS2R
Structure
Comment
Generic compound in reaction hierarchy
The oxidized lipoyllysine residue in EC 2.3.1.12, dihydrolipoyllysine-residue acetyltransferase ( EC 2.3.1.61, dihydrolipoyllysine-residue succinyltransferase or EC 2.3.1.168, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase ).
Reaction
R01699 R01700 R01701 R01702 R01940 R03270 R03316 R04225
R07600 R07602 R07604 R07618 R10997 R12426 R12435 R12449
R12450 R12603 R13167 R13186
Pathway
map00010  Glycolysis / Gluconeogenesis
map00020  Citrate cycle (TCA cycle)
map00280  Valine, leucine and isoleucine degradation
map00310  Lysine degradation
map00620  Pyruvate metabolism
map00640  Propanoate metabolism
map00785  Lipoic acid metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Network
nt06024  Valine, leucine and isoleucine degradation
nt06031  Citrate cycle and pyruvate metabolism
nt06032  Lipoic acid metabolism
nt06036  Lysine degradation
Enzyme
1.2.4.1         1.2.4.2         1.2.4.4         1.2.4.-         
1.8.1.4         1.11.1.28       2.3.1.200       2.3.1.313       
6.3.1.20
Other DBs
PubChem: 47205285
ChEBI: 80218
LinkDB
KCF data

ATOM        13
            1   S3x S    14.9894  -14.4968
            2   S3x S    13.5885  -14.4968
            3   C1x C    13.1557  -15.8291
            4   C1x C    14.2890  -16.6526
            5   C1y C    15.4223  -15.8291
            6   C1b C    16.6229  -16.5281
            7   C1b C    17.8362  -15.8276
            8   C1b C    19.0493  -16.5281
            9   C1b C    20.2625  -15.8276
            10  C5a C    21.4758  -16.5281
            11  N1b N    22.6890  -15.8276
            12  O5a O    21.4758  -17.9290
            13  R   R    24.0899  -15.8276
BOND        13
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     5   6 1 #Down
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   10  12 2
            13   11  13 1

» Japanese version

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