KEGG   DRUG: トリクロルメチアジド
エントリ  
D00658                      Drug                                   
一般名   
トリクロルメチアジド (JP18);
Trichlormethiazide (JP18/USP/INN)
商品名   
フルイトラン (シオノギファーマ)
  後発品
トリクロルメチアジド (コーアイセイ), トリクロルメチアジド (ニプロ), トリクロルメチアジド (日医工), トリクロルメチアジド (日医工岐阜工場), トリクロルメチアジド (日本ジェネリック), トリクロルメチアジド (東和薬品), トリクロルメチアジド (辰巳化学), トリクロルメチアジド (鶴原製薬)
組成式   
C8H8Cl3N3O4S2
質量    
378.9022
分子量   
380.6558
構造式   
Simcomp   
クラス   
心血管系用薬
 DG03231  血圧降下薬
  DG01749  チアジド系利尿薬
 DG01690  スルホンアミド系利尿薬
  DG01749  チアジド系利尿薬
コード   
同一コード: C07767
薬効分類: 2132
ATCコード: C03AA06
商品: D00658<JP>
商品 (mixture): D10480<JP>
効能    
血圧降下薬, 利尿薬, Na+-Cl-再吸収阻害薬
  疾患
高血圧症 [DS:H01633]
コメント  
チアジド系
ターゲット 
SLC12A3 (TSC) [HSA:6559] [KO:K14426]
SLC12A1 (NKCC2) [HSA:6557] [KO:K14425]
相互作用  

構造マップ 
map07017  スルホンアミド誘導体 - 利尿剤
map07233  イオントランスポーター阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   213  利尿剤
    2132  チアジド系製剤
     D00658  トリクロルメチアジド (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C03 利尿薬
   C03A 低許容値の利尿薬、チアジド
    C03AA チアジド、単剤
     C03AA06 トリクロルメチアジド
      D00658  トリクロルメチアジド (JP18) <JP>
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG03231  血圧降下薬
   DG01749  チアジド系利尿薬
    D00658  トリクロルメチアジド
  DG01690  スルホンアミド系利尿薬
   DG01749  チアジド系利尿薬
    D00658  トリクロルメチアジド
医薬品クラス [BR:jp08332]
 心血管系用薬
  DG03231  血圧降下薬 [商品一覧]
   D00658  トリクロルメチアジド
ターゲットに基づく医薬品分類 [BR:jp08310]
 トランスポーター
  SLC ファミリー
   SLC12
    SLC12A1 (NKCC2)
     D00658  トリクロルメチアジド (JP18) <JP>
    SLC12A3 (TSC)
     D00658  トリクロルメチアジド (JP18) <JP>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00658  トリクロルメチアジド
  D00658  トリクロルメチアジド錠
リンク   
CAS: 133-67-5
PubChem: 7847724
LigandBox: D00658
日化辞: J2.527E
LinkDB    

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KEGG   DRUG: ヒドロクロロチアジド
エントリ  
D00340                      Drug                                   
一般名   
ヒドロクロロチアジド (JP18);
Hydrochlorothiazide (JP18/USP/INN)
商品名   
  後発品
ヒドロクロロチアジド (東和薬品), ヒドロクロロチアジド (東和薬品)
米国の商品 
  後発品
HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (Accord Healthcare), HYDROCHLOROTHIAZIDE (Actavis Pharma), HYDROCHLOROTHIAZIDE (Actavis Pharma), HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals Limited), HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals), HYDROCHLOROTHIAZIDE (American Health Packaging), HYDROCHLOROTHIAZIDE (American Health Packaging), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aurobindo Pharma Limited), HYDROCHLOROTHIAZIDE (Aurobindo Pharma Limited), HYDROCHLOROTHIAZIDE (AvPAK), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Chartwell RX), HYDROCHLOROTHIAZIDE (DIRECT RX), HYDROCHLOROTHIAZIDE (Denton Pharma), HYDROCHLOROTHIAZIDE (Denton Pharma), HYDROCHLOROTHIAZIDE (Direct RX), HYDROCHLOROTHIAZIDE (Direct_Rx), HYDROCHLOROTHIAZIDE (Direct_Rx), HYDROCHLOROTHIAZIDE (Direct_Rx), HYDROCHLOROTHIAZIDE (Exelan Pharmaceuticals), HYDROCHLOROTHIAZIDE (Golden State Medical Supply), HYDROCHLOROTHIAZIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), HYDROCHLOROTHIAZIDE (JUBILANT CADISTA PHARMACEUTICALS), HYDROCHLOROTHIAZIDE (Lake Erie Medical DBA Quality Care Products LLC), HYDROCHLOROTHIAZIDE (Lannett Company), HYDROCHLOROTHIAZIDE (Leading Pharma), HYDROCHLOROTHIAZIDE (Legacy Pharmaceutical Packaging), HYDROCHLOROTHIAZIDE (NCS HealthCare of KY), HYDROCHLOROTHIAZIDE (NCS HealthCare of KY), HYDROCHLOROTHIAZIDE (NCS HealthCare of KY), HYDROCHLOROTHIAZIDE (NCS HealthCare of KY), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare PHarmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (Oxford Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (Quality Care Products LLC), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (RPK Pharmaceuticals), HYDROCHLOROTHIAZIDE (RPK Pharmaceuticals), HYDROCHLOROTHIAZIDE (RPK Pharmaceuticals), HYDROCHLOROTHIAZIDE (RPK Pharmaceuticals), HYDROCHLOROTHIAZIDE (Redpharm Drug), HYDROCHLOROTHIAZIDE (Redpharm drug), HYDROCHLOROTHIAZIDE (Rising Pharma Holdings), HYDROCHLOROTHIAZIDE (ST. MARY'S MEDICAL PARK PHARMACY), HYDROCHLOROTHIAZIDE (ScieGen Pharmaceuticals), HYDROCHLOROTHIAZIDE (ScieGen Pharmaceuticals), HYDROCHLOROTHIAZIDE (Solco Healthcare U.S.), HYDROCHLOROTHIAZIDE (St. Mary's Medical Park Pharmacy), HYDROCHLOROTHIAZIDE (St. Mary's Medical Park Pharmacy), HYDROCHLOROTHIAZIDE (St. Mary's Medical Park Pharmacy), HYDROCHLOROTHIAZIDE (St. Mary's Medical Park Pharmacy), HYDROCHLOROTHIAZIDE (Teva Pharmaceuticals USA), HYDROCHLOROTHIAZIDE (Unichem Pharmaceuticals (USA)), HYDROCHLOROTHIAZIDE (Unichem Pharmaceuticals (USA)), HYDROCHLOROTHIAZIDE (Westminster Pharmaceuticals)
組成式   
C7H8ClN3O4S2
質量    
296.9645
分子量   
297.7391
構造式   
Simcomp   
クラス   
心血管系用薬
 DG03231  血圧降下薬
  DG01749  チアジド系利尿薬
 DG01690  スルホンアミド系利尿薬
  DG01749  チアジド系利尿薬
コード   
同一コード: C07041
薬効分類: 2132 2149
ATCコード: C03AA03
商品: D00340<JP/US>
商品 (mixture): D07895<JP/US> D09196<JP/US> D09197<JP/US> D09219<JP/US> D10249<US> D10268<US> D10269<US> D10270<US> D10271<US> D10273<US> D10275<US> D10276<US> D10277<US> D10278<US> D10279<US> D10280<US> D10284<US> D10286<US> D10288<US> D10805<JP>
効能    
血圧降下薬, 利尿薬, Na+-Cl-再吸収阻害薬
  疾患
高血圧症 [DS:H01633]
コメント  
チアジド系
ターゲット 
SLC12A3 (TSC) [HSA:6559] [KO:K14426]
相互作用  

構造マップ 
map07017  スルホンアミド誘導体 - 利尿剤
map07233  イオントランスポーター阻害薬
他のマップ 
map04976  胆汁の分泌
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   213  利尿剤
    2132  チアジド系製剤
     D00340  ヒドロクロロチアジド (JP18)
   214  血圧降下剤
    2149  その他の血圧降下剤
     D00340  ヒドロクロロチアジド (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C03 利尿薬
   C03A 低許容値の利尿薬、チアジド
    C03AA チアジド、単剤
     C03AA03 ヒドロクロロチアジド
      D00340  ヒドロクロロチアジド (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  チアジド系利尿薬
   ヒドロクロロチアジド
    D00340  ヒドロクロロチアジド (JP18)
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG03231  血圧降下薬
   DG01749  チアジド系利尿薬
    D00340  ヒドロクロロチアジド
  DG01690  スルホンアミド系利尿薬
   DG01749  チアジド系利尿薬
    D00340  ヒドロクロロチアジド
医薬品クラス [BR:jp08332]
 心血管系用薬
  DG03231  血圧降下薬 [商品一覧]
   D00340  ヒドロクロロチアジド
ターゲットに基づく医薬品分類 [BR:jp08310]
 トランスポーター
  SLC ファミリー
   SLC12
    SLC12A3 (TSC)
     D00340  ヒドロクロロチアジド (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00340  ヒドロクロロチアジド
リンク   
CAS: 58-93-5
PubChem: 7847406
PDB-CCD: HCZ[PDBj]
LigandBox: D00340
日化辞: J1.920H
LinkDB    

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