KEGG ORTHOLOGY: K12865

ORTHOLOGY: K12865

Entry

K12865                      KO

Symbol

PQBP1, NPW38

Name

polyglutamine-binding protein 1

Pathway

map03040

Spliceosome

Disease

H01913

Renpenning syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    K12865  PQBP1, NPW38; polyglutamine-binding protein 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K12865  PQBP1, NPW38; polyglutamine-binding protein 1
Spliceosome [BR:ko03041]
Complex B
  Other components
   Prp19 complex
    K12865  PQBP1, NPW38; polyglutamine-binding protein 1

Genes

HSA:	10084(PQBP1)

PTR:	739437(PQBP1)

PPS:	100980569(PQBP1)

GGO:	101150130(PQBP1)

PON:	100455390(PQBP1)

PPYG:

129024428(PQBP1)

NLE:	100600773(PQBP1)

HMH:	116811669(PQBP1)

SSYN:

129475787(PQBP1)

MCC:	711678(PQBP1)

MCF:	102138992(PQBP1)

MTHB:

126945608

MNI:	105493910(PQBP1)

CSAB:

103231945(PQBP1)

CATY:

105573122(PQBP1)

PANU:

101011433(PQBP1)

TGE:	112615440(PQBP1)

MLEU:

105547717(PQBP1)

RRO:	104661798(PQBP1)

RBB:	108539568(PQBP1)

TFN:	117077492(PQBP1)

PTEH:

111535707(PQBP1)

CANG:

105507932 105515005(PQBP1)

CJC:	100402469(PQBP1)

SBQ:	101028129(PQBP1) 101029170

CIMI:

108300906(PQBP1)

ANAN:

105730425(PQBP1)

CSYR:

103268710(PQBP1)

MMUR:

105856387(PQBP1)

LCAT:

123628377(PQBP1)

PCOQ:

105811484 105816826(PQBP1)

OGA:	100958756(PQBP1)

MMU:	54633(Pqbp1)

MCAL:

110286902(Pqbp1)

MPAH:

110313646(Pqbp1)

RNO:	302557(Pqbp1)

MCOC:

116104612(Pqbp1)

ANU:	117694435(Pqbp1)

MUN:	110561987(Pqbp1)

CGE:	100762531(Pqbp1)

MAUA:

101835546(Pqbp1)

PROB:

127216696(Pqbp1)

PLEU:

114701301(Pqbp1)

MORG:

121442597 121442655(Pqbp1) 121445344

MFOT:

126512823

AAMP:

119805054(Pqbp1)

NGI:	103741654(Pqbp1)

HGL:	101709749(Pqbp1)

CPOC:

100732065(Pqbp1)

CCAN:

109692138(Pqbp1)

DORD:

105997843(Pqbp1)

DSP:	122098770(Pqbp1)

PLOP:

125343320(Pqbp1)

NCAR:

124972586

MMMA:

107159843(Pqbp1)

OCU:

100345368

OPI:	101516360(PQBP1)

TUP:	102489460(PQBP1)

GVR:	103589444(PQBP1)

CFA:	480909(PQBP1)

CLUD:

112673130(PQBP1)

VVP:	112907307(PQBP1)

VLG:	121474790 121482501(PQBP1)

NPO:	129518580(PQBP1)

AML:	100471676(PQBP1)

UMR:	103663204(PQBP1)

UAH:	113265934(PQBP1)

ELK:

111150420

LLV:

125091273

MPUF:

101678867(PQBP1)

MNP:	132007505(PQBP1)

MLK:	131822170(PQBP1)

NVS:	122896770(PQBP1)

ORO:	101382300(PQBP1)

EJU:	114216773(PQBP1)

ZCA:	113930730(PQBP1)

MLX:	118010111(PQBP1)

NSU:	110570822(PQBP1)

LWW:	102735872(PQBP1)

FCA:	101097213(PQBP1)

PYU:	121025944(PQBP1)

PCOO:

112870878(PQBP1)

PBG:	122476856(PQBP1)

PVIV:

125157612(PQBP1)

LRUF:

124509518

PTG:	102971510(PQBP1)

PPAD:

109248081(PQBP1)

PUC:

125931667

AJU:

106989014

HHV:	120221022(PQBP1)

BTA:	534894(PQBP1)

BOM:	102268754(PQBP1)

BIU:	109555234(PQBP1)

BBUB:

102410319(PQBP1)

BBIS:

104991758(PQBP1)

CHX:	102172047(PQBP1)

OAS:	101107670(PQBP1)

BTAX:

128069981(PQBP1)

ODA:	120882107(PQBP1)

CCAD:

122434830(PQBP1)

MBEZ:

129564514(PQBP1)

SSC:	100620849(PQBP1)

CFR:	102506378(PQBP1)

CBAI:

105079400(PQBP1)

CDK:	105103302(PQBP1)

VPC:	102535533(PQBP1)

BACU:

103007677(PQBP1)

BMUS:

118889150(PQBP1)

LVE:	103089847(PQBP1)

OOR:	101287271(PQBP1)

DLE:	111169520(PQBP1)

PCAD:

102993180(PQBP1)

PSIU:

116747319(PQBP1)

NASI:

112416010(PQBP1)

ECB:	100062415(PQBP1)

EPZ:	103545448(PQBP1)

EAI:	106826969(PQBP1)

MYB:	102260046(PQBP1)

MYD:	102765477(PQBP1)

MMYO:

118653741(PQBP1) 118662771

MLF:	102427257(PQBP1)

MDT:	132223934(PQBP1) 132242662

PKL:	118731779(PQBP1)

EFUS:

103301290(PQBP1)

MNA:	107541407(PQBP1)

DRO:	112322453(PQBP1)

SHON:

118998328(PQBP1)

AJM:	119059731(PQBP1)

PDIC:

114505293(PQBP1)

PHAS:

123832725(PQBP1)

MMF:	118635834(PQBP1)

PPAM:

129065214(PQBP1)

HAI:	109374793(PQBP1)

RFQ:	117023459(PQBP1)

PALE:

102886945(PQBP1)

PGIG:

120587083(PQBP1)

PVP:	105310004(PQBP1)

RAY:	107515018(PQBP1)

MJV:	108404040(PQBP1)

TOD:	119246172(PQBP1)

SARA:

101543887(PQBP1)

SETR:

125999233(PQBP1)

LAV:	100666288(PQBP1)

TMU:

101346309

ETF:	101640619(PQBP1)

DNM:	101435637(PQBP1)

MDO:	100013763(PQBP1) 100013919

GAS:	123239555 123254160

SHR:	100917631(PQBP1) 100925250

AFZ:	127543264 127553942

PCW:	110201020(PQBP1)

TVP:	118833290(PQBP1) 118839614 118844152

OAA:	100090224(PQBP1)

ACYG:

136787525(PQBP1)

PMOA:

120512586(PQBP1)

OMA:	130266182(PQBP1)

PHI:	102109331(PQBP1)

CCW:	120412231(PQBP1)

ZLE:	135460814(PQBP1)

SVG:	106864628(PQBP1)

SHAB:

115602990(PQBP1)

PLET:

104628413(PQBP1)

CUCA:

104055627(PQBP1)

NPD:	112957828(PQBP1)

ASN:	102380196(PQBP1)

AMJ:	102570418(PQBP1)

CMY:	102934144(PQBP1)

CCAY:

125628277(PQBP1)

DCC:	119847164(PQBP1)

CPIC:

101932832(PQBP1)

CABI:

116823954(PQBP1)

MRV:	120388190(PQBP1)

ACS:	100565787(pqbp1)

ASAO:

132767811(PQBP1)

PVT:	110090608(PQBP1)

SUND:

121920903(PQBP1)

PBI:	103062760(PQBP1)

PMUR:

107286562(PQBP1)

CTIG:

120299544(PQBP1)

TSR:	106549453(PQBP1)

PGUT:

117675440(PQBP1)

APRI:

131190204(PQBP1)

PTEX:

113443379(PQBP1)

NSS:	113417763(PQBP1)

VKO:	123030032(PQBP1)

PMUA:

114587916(PQBP1)

PRAF:

128404722(PQBP1)

ZVI:	118097779(PQBP1)

HCG:	128344187(PQBP1)

GJA:	107116236(PQBP1)

STOW:

125428177(PQBP1)

EMC:	129346276(PQBP1)

XLA:	432267(pqbp1.S) 496143(pqbp1.L)

XTR:	100216040(pqbp1)

NPR:	108788255(PQBP1)

RTEM:

120914083(PQBP1)

BBUF:

121009197(PQBP1)

BGAR:

122946432(PQBP1)

MUO:	115463436 115463440(PQBP1)

GSH:	117349940(PQBP1)

DRE:	796523(pqbp1)

SRX:	107747222 107749677(pqbp1)

SANH:

107683912 107702814

SGH:	107575439(pqbp1) 107578050 107580803

CCAR:

109071706(pqbp1) 109082062

CAUA:

113107383(pqbp1)

CGIB:

127962938

PTET:

122349952(pqbp1) 122350746

LROH:

127169263(pqbp1)

OMC:	131546225(pqbp1)

PPRM:

120479325(pqbp1)

RKG:	130081928(pqbp1)

MAMB:

125280541(pqbp1)

CIDE:

127517129 127517359

CERY:

137026577(pqbp1)

MASI:

127414891 127424559

TROS:

130568594(pqbp1)

TDW:	130407292(pqbp1)

MANU:

129414684(pqbp1)

IPU:

108265668

IFU:	128607467(pqbp1)

PHYP:

113533191(pqbp1)

SMEO:

124399487(pqbp1)

TFD:	113656101(pqbp1)

TVC:	132853804(pqbp1)

TRN:	134317872(pqbp1)

AMEX:

103024004(pqbp1)

CMAO:

118812941(pqbp1)

EEE:	113578761(pqbp1)

CHAR:

105893649(pqbp1)

TRU:	101077165(pqbp1)

TFS:	130529958(pqbp1)

LCO:	104932127(pqbp1)

NCC:	104943901(pqbp1)

TBEN:

117477460(pqbp1)

CGOB:

115010842(pqbp1)

PGEO:

117449347(pqbp1)

GACU:

117563154(pqbp1)

EMAC:

134870863(pqbp1)

ELY:	117258491(pqbp1)

EFO:	125891526(pqbp1)

PLEP:

121946777(pqbp1)

SLUC:

116043608(pqbp1)

ECRA:

117947034(pqbp1)

ESP:	116692886(pqbp1)

PFLV:

114558493(pqbp1)

GAT:	120828761(pqbp1)

PPUG:

119222688(pqbp1)

AFB:	129099644(pqbp1)

CLUM:

117733575(pqbp1)

PSWI:

130199699(pqbp1)

MSAM:

119905312(pqbp1)

SCHU:

122882954(pqbp1)

CUD:	121517693(pqbp1)

ALAT:

119022439(pqbp1)

MZE:	101472313(pqbp1)

ONL:	100700881(pqbp1)

OAU:	116319516(pqbp1)

OLA:	101167869(pqbp1)

OML:	112159281(pqbp1)

CSAI:

133456702(pqbp1)

XMA:	102227044(pqbp1)

XCO:	114142793(pqbp1)

XHE:	116708521(pqbp1)

PRET:

103467716(pqbp1)

PFOR:

103139060(pqbp1)

PLAI:

106954596(pqbp1)

PMEI:

106915892(pqbp1)

GAF:	122828981(pqbp1)

PPRL:

129370140(pqbp1)

CVG:	107095958(pqbp1)

CTUL:

119799442(pqbp1)

GMU:	124867609(pqbp1)

NFU:	107390501(pqbp1)

KMR:	108232119(pqbp1)

ALIM:

106519352(pqbp1)

NWH:	119416847(pqbp1)

AOCE:

111580271(pqbp1)

MCEP:

125018596(pqbp1)

CSEM:

103385388(pqbp1)

POV:	109642988(pqbp1)

SSEN:

122777522(pqbp1)

HHIP:

117764498(pqbp1)

HSP:	118110977(pqbp1)

PPLT:

128443032(pqbp1)

SMAU:

118316677(pqbp1)

LCF:

108882183

SDU:	111235068(pqbp1)

SLAL:

111654201(pqbp1)

XGL:	120803593(pqbp1)

HCQ:	109513016(pqbp1)

SSCV:

125988639

SBIA:

133514536(pqbp1)

PEE:	133401425(pqbp1)

PTAO:

133476795(pqbp1)

BPEC:

110164839(pqbp1)

MALB:

109966722(pqbp1)

BSPL:

114858510(pqbp1)

SJO:	128357400(pqbp1)

SASA:

100286483(pqbp1)

STRU:

115165734 115168071

OTW:	112221900(pqbp1)

OMY:	110492769(pqbp1)

OGO:	124045932(pqbp1)

ONE:	115102371(pqbp1)

OKI:	109869393(pqbp1)

OKE:	118359891(pqbp1)

SALP:

111976513

SNH:	120061150(pqbp1)

CCLU:

121538090 121545670

ELS:	105022364(pqbp1)

SFM:	108918177(pqbp1)

PKI:	111857081(pqbp1)

AANG:

118211779(pqbp1)

LOC:	102683840(pqbp1)

PSPA:

121305527(pqbp1)

ARUT:

117401783(pqbp1)

PSEX:

120542887(pqbp1)

LCM:	102367299(PQBP1)

PMRN:

116947605(PQBP1)

LRJ:	133351645(PQBP1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG11820(PQBP1)

DER:

6555319

DSE:

6619645

DSI:	Dsimw501_GD21167(Dsim_GD21167)

DYA:	Dyak_GE23551

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI23959

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ002807

CPII:

CNS:

BCOO:

AME:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105670272(PQBP1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

SOY:

AGRG:

ATD:

CSET:

AGB:	108916287 111691314

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_202310

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:	119828643 119828644

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103518768 113465688

CLEC:

106661837

HHAL:

106677281(PQBP1)

NLU:

111049999

HVI:	124355310 124355315

MQU:	128997180 128997261

PHU:	Phum_PHUM600860

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_221611

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

DSV:	119434474 119434559

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136975880(PQBP1)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_T21D12.3(pqbp-1.1)

CBR:	CBG_10545(Cbr-pqbp-1.2)

CRQ:	GCK72_016361

NAI:	NECAME_00439

BMY:	BM_BM5892(Bma-pqbp-1.1)

LOA:	LOAG_18055

TSP:

Tsp_00320

HRO:	HELRODRAFT_186200

LGI:	LOTGIDRAFT_116530

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:	111106083 111109660

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_089630

OVI:	T265_09249

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:	107331077 107331166

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_55399

AQU:	100634796 100639908

ATH:

AT2G41020

ALY:

9317822

CRB:

17887809

CSAT:

104782591 104785291 109124549

EUS:	EUTSA_v10002504mg

BRP:

103865858

BNA:	106391634 106431122

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10011646mg

PVY:

MINC:

TCC:

GRA:

GHI:	107925934 121209481

GAB:

HSYR:

DZI:

EGR:

GMX:

GSJ:

PVU:	PHAVU_007G243700g

VRA:

106772409

VAR:

108326172

VUN:

114167130

VUM:	124848561 124848562

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

ADU:

AIP:

AHF:	112727530 112789652

LANG:

109354810

PCIN:

129317708

QSA:	O6P43_006299

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:	103928008 103966214

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107760870 107821129

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130786618 130788415

BVG:

104889567

SOE:

110804226

CQI:	110711536 110714712

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

OBR:

OGL:

BDI:

ATS:	109738129 109774263

TDC:	119270056 119278103

TAES:

123063058 123071951 123080258

TUA:	125528341 125545772

LPER:

LRD:

SBI:

ZMA:

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	122002176 122006424

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

PPP:

CSL:	COCSUDRAFT_18221

OLU:	OSTLU_33395

OTA:	OT_ostta09g01020

BPG:	Bathy10g03460

MIS:	MICPUN_57153

MPP:	MICPUCDRAFT_56227

» show all

Reference

PMID:12062018

Authors

Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I

Title

Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.

Journal

Neuron 34:701-13 (2002)
DOI:10.1016/S0896-6273(02)00697-9

Sequence

[hsa:10084]

LinkDB

DBGET integrated database retrieval system