KEGG   REACTION: R03869
Entry
R03869                      Reaction                               
Name
(S)-methylmalonate semialdehyde:NAD+ oxidoreductase
Definition
(S)-Methylmalonate semialdehyde + NAD+ + H2O <=> Methylmalonate + NADH + H+
Equation
C06002 + C00003 + C00001 <=> C02170 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00242  C02170_C06002
Enzyme
1.2.1.3
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.3
     R03869  (S)-Methylmalonate semialdehyde + NAD+ + H2O <=> Methylmalonate + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.2.1.3
   R00538  Aldehyde <=> Carboxylate
    R03869  (S)-Methylmalonate semialdehyde <=> Methylmalonate
Orthology
K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00149  aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K14085  aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Other DBs
RHEA: 31046
LinkDB

KEGG   RCLASS: RC00242
Entry
RC00242                     RClass                                 
Definition
C4a-C6a:*-O6a:C1c+O4a-C1c+O6a
Reactant pair
C00082_C22021    C00118_C00197    C00135_C01929
C00186_C00424    C00256_C00937    C00258_C00577
C00279_C03393    C01301_C04722    C02170_C06002
C04554_C05445    C05577_C05580    C05583_C05584
C05938_C05947    C11499_C21181    C16587_C16591
C20839_C21305    C21076_C21304
Related class
Reaction
R01058 R01163 R01446 R01735 R01752 R01825 R03506 R03869
R03871 R03872 R04506 R04882 R04883 R04891 R04892 R05051
R07159 R08307 R08571 R08760 R08761 R10324 R10615 R10860
R11356 R11360 R11677 R11678 R12235
Enzyme
1.1.1.23        1.2.1.3         1.2.1.5         1.2.1.9         
1.2.1.22        1.2.1.23        1.2.1.72        1.2.1.88        
1.2.1.89        1.2.1.90        1.2.1.97        1.2.1.101       
1.2.3.1         1.2.7.5         1.2.7.6         1.2.99.8        
1.14.15.15      1.14.15.28      1.14.15.29
Pathway
rn00010  Glycolysis / Gluconeogenesis
rn00030  Pentose phosphate pathway
rn00120  Primary bile acid biosynthesis
rn00280  Valine, leucine and isoleucine degradation
rn00330  Arginine and proline metabolism
rn00340  Histidine metabolism
rn00350  Tyrosine metabolism
rn00561  Glycerolipid metabolism
rn00620  Pyruvate metabolism
rn00640  Propanoate metabolism
rn00750  Vitamin B6 metabolism
rn00982  Drug metabolism - cytochrome P450
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
Orthology
K00013  histidinol dehydrogenase [EC:1.1.1.23]
K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00129  aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00131  glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]
K00149  aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K00157  aldehyde oxidase [EC:1.2.3.1]
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K00488  cholestanetriol 26-monooxygenase [EC:1.14.15.15]
K03472  D-erythrose 4-phosphate dehydrogenase [EC:1.2.1.72]
K03738  aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
K07248  lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase [EC:1.2.1.22 1.2.1.21]
K11389  glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) [EC:1.2.7.6]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
K14085  aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
K16046  cholest-4-en-3-one 26-monooxygenase [EC:1.14.15.28]
K18020  glyceraldehyde dehydrogenase large subunit [EC:1.2.99.8]
K18021  glyceraldehyde dehydrogenase medium subunit [EC:1.2.99.8]
K18022  glyceraldehyde dehydrogenase small subunit [EC:1.2.99.8]
K18128  D-glyceraldehyde dehydrogenase (NADP+) [EC:1.2.1.89]
K18978  glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90]
K19266  lactaldehyde dehydrogenase [EC:1.2.1.22]

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