KEGG   PATHWAY: amaa00230
Entry
amaa00230                   Pathway                                
Name
Purine metabolism - Alteromonas mediterranea DE1
Class
Metabolism; Nucleotide metabolism
Pathway map
amaa00230  Purine metabolism
amaa00230

Module
amaa_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:amaa00230]
amaa_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:amaa00230]
amaa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:amaa00230]
amaa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:amaa00230]
amaa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:amaa00230]
amaa_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:amaa00230]
Other DBs
GO: 0006163 0042278
Organism
Alteromonas mediterranea DE1 [GN:amaa]
Gene
amad1_03180  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
amad1_07550  hypothetical protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
amad1_19615  nudE; adenosine nucleotide hydrolase NudE [KO:K08312] [EC:3.6.1.-]
amad1_07830  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
amad1_07715  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
amad1_12635  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
amad1_19460  Phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
amad1_11260  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
amad1_04945  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
amad1_11255  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
amad1_02620  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
amad1_02615  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
amad1_11190  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
amad1_09625  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
amad1_19450  bifunctionalphosphoribosylaminoimidazolecarboxam ide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
amad1_13180  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
amad1_19610  HAD-superfamily hydrolase [KO:K20881] [EC:3.1.3.-]
amad1_05430  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
amad1_13245  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
amad1_13710  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
amad1_13770  mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase [KO:K00940] [EC:2.7.4.6]
amad1_19605  inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
amad1_04525  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
amad1_08020  putative xanthine dehydrogenase subunit XdhA [KO:K13481] [EC:1.17.1.4]
amad1_08015  xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
amad1_14465  xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
amad1_14460  putative oxidoreductase subunit [KO:K11178] [EC:1.17.1.4]
amad1_14455  putative oxidoreductase [KO:K13483]
amad1_13705  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
amad1_07995  guanine deaminase [KO:K01487] [EC:3.5.4.3]
amad1_00705  guanylate kinase [KO:K00942] [EC:2.7.4.8]
amad1_11155  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
amad1_11160  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
amad1_11715  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
amad1_11655  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
amad1_11710  metal dependent phosphohydrolase [KO:K08722] [EC:3.1.3.89]
amad1_12055  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
amad1_00715  bifunctional (p)ppGpp synthetase II/guanosine-3,5-bis pyrophosphate 3-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
amad1_04110  putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
amad1_02580  guanosine pentaphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
amad1_03750  relA; (p)ppGpp synthetase I/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
amad1_02175  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
amad1_09620  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
amad1_14420  adenylate cyclase [KO:K05851] [EC:4.6.1.1]
amad1_02670  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
amad1_04755  hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
amad1_08050  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
amad1_15510  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
amad1_13140  adenylate kinase [KO:K00939] [EC:2.7.4.3]
amad1_03755  MazG protein [KO:K04765] [EC:3.6.1.9]
amad1_03190  3,5-cyclic-nucleotide phosphodiesterase [KO:K03651] [EC:3.1.4.53]
amad1_03675  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
amad1_06600  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
amad1_06590  sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
amad1_06605  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
amad1_08000  transthyretin [KO:K07127] [EC:3.5.2.17]
amad1_08005  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
amad1_08035  hypothetical protein [KO:K16842] [EC:3.5.2.5]
amad1_08100  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
amad1_08105  class V aminotransferase [KO:K00839] [EC:2.6.1.112]
amad1_08115  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
amaa00030  Pentose phosphate pathway
amaa00220  Arginine biosynthesis
amaa00250  Alanine, aspartate and glutamate metabolism
amaa00260  Glycine, serine and threonine metabolism
amaa00340  Histidine metabolism
amaa00630  Glyoxylate and dicarboxylate metabolism
amaa00730  Thiamine metabolism
amaa00740  Riboflavin metabolism
amaa00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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