KEGG   PATHWAY: apel00230
Entry
apel00230                   Pathway                                
Name
Purine metabolism - Alteromonas pelagimontana
Class
Metabolism; Nucleotide metabolism
Pathway map
apel00230  Purine metabolism
apel00230

Module
apel_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:apel00230]
apel_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:apel00230]
apel_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:apel00230]
apel_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:apel00230]
apel_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:apel00230]
apel_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:apel00230]
apel_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:apel00230]
Other DBs
GO: 0006163 0042278
Organism
Alteromonas pelagimontana [GN:apel]
Gene
CA267_002360  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CA267_006120  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CA267_008550  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
CA267_002110  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CA267_002215  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CA267_016495  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CA267_008410  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CA267_000500  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CA267_012010  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
CA267_014010  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CA267_000495  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CA267_006770  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CA267_006775  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
CA267_000415  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CA267_017480  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CA267_008400  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CA267_015965  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CA267_006290  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
CA267_008545  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
CA267_002250  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
CA267_015890  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CA267_015435  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
CA267_015380  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CA267_008540  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
CA267_013580  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CA267_001410  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
CA267_001415  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
CA267_010690  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
CA267_010695  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
CA267_010700  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
CA267_015440  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
CA267_001435  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
CA267_010295  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CA267_000360  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CA267_000365  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CA267_013435  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
CA267_000795  deoxyguanosinetriphosphate triphosphohydrolase family protein [KO:K01129] [EC:3.1.5.1]
CA267_016890  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
CA267_000790  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
CA267_010305  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CA267_005205  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CA267_006810  guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CA267_005470  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
CA267_007195  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CA267_017475  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CA267_006710  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CA267_001370  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CA267_013820  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
CA267_001385  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
CA267_016160  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
CA267_005465  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
CA267_006110  3',5'-cyclic-nucleotide phosphodiesterase [KO:K03651] [EC:3.1.4.53]
CA267_005540  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
CA267_003290  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CA267_003300  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
CA267_003285  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
CA267_001430  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
CA267_001425  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
CA267_001400  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
CA267_001360  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
CA267_001355  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
CA267_001345  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
apel00030  Pentose phosphate pathway
apel00220  Arginine biosynthesis
apel00250  Alanine, aspartate and glutamate metabolism
apel00260  Glycine, serine and threonine metabolism
apel00340  Histidine metabolism
apel00630  Glyoxylate and dicarboxylate metabolism
apel00730  Thiamine metabolism
apel00740  Riboflavin metabolism
apel00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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