KEGG   PATHWAY: bit00230
Entry
bit00230                    Pathway                                
Name
Purine metabolism - Bacillus spizizenii
Class
Metabolism; Nucleotide metabolism
Pathway map
bit00230  Purine metabolism
bit00230

Module
bit_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bit00230]
bit_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bit00230]
bit_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bit00230]
bit_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bit00230]
Other DBs
GO: 0006163 0042278
Organism
Bacillus spizizenii [GN:bit]
Gene
BIS30_01475  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BIS30_01405  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
BIS30_15345  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BIS30_10670  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BIS30_13850  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BIS30_13870  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BIS30_13860  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BIS30_11655  purT; phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
BIS30_13845  phosphoribosylformylglycinamidine synthase [KO:K23269] [EC:6.3.5.3]
BIS30_13835  phosphoribosylformylglycinamidine synthase [KO:K23264] [EC:6.3.5.3]
BIS30_13840  phosphoribosylformylglycinamidine synthase [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BIS30_13855  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
BIS30_13820  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
BIS30_13815  N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BIS30_13830  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BIS30_13825  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BIS30_13865  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BIS30_03200  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BIS30_05745  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
BIS30_01400  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
BIS30_00345  purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
BIS30_18525  laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BIS30_10765  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BIS30_10425  inosine-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BIS30_01015  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BIS30_03595  nucleoside-triphosphate diphosphatase [KO:K01519] [EC:3.6.1.66]
BIS30_00675  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
BIS30_05810  xanthine dehydrogenase [KO:K00087] [EC:1.17.1.4]
BIS30_05595  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
BIS30_17365  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BIS30_18685  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BIS30_19570  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BIS30_19575  ribonucleotide-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
BIS30_10460  deoxyguanosine kinase [KO:K15518] [EC:2.7.1.113]
BIS30_03195  (p)ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BIS30_16505  GTP pyrophosphokinase [KO:K07816] [EC:2.7.6.5]
BIS30_09005  GTP pyrophosphokinase [KO:K07816] [EC:2.7.6.5]
BIS30_10075  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BIS30_10455  deoxycytidine kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
BIS30_18070  adenine deaminase [KO:K01486] [EC:3.5.4.2]
BIS30_13890  adenine deaminase [KO:K01486] [EC:3.5.4.2]
BIS30_14515  cpdB; 2', 3'-cyclic nucleotide 2'-phosphodiesterase [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
BIS30_19335  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
BIS30_11135  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BIS30_16165  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BIS30_18645  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BIS30_16170  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
BIS30_18640  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
BIS30_05785  uricase [KO:K16838] [EC:1.7.3.3 4.1.1.97]
BIS30_05790  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BIS30_05765  allantoinase [KO:K01466] [EC:3.5.2.5]
BIS30_05835  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
BIS30_05830  aminotransferase V [KO:K00839] [EC:2.6.1.112]
BIS30_08010  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BIS30_08015  urease subunit beta [KO:K01429] [EC:3.5.1.5]
BIS30_08020  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
BIS30_07705  gamma-glutamyltranspeptidase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bit00030  Pentose phosphate pathway
bit00220  Arginine biosynthesis
bit00250  Alanine, aspartate and glutamate metabolism
bit00260  Glycine, serine and threonine metabolism
bit00340  Histidine metabolism
bit00630  Glyoxylate and dicarboxylate metabolism
bit00730  Thiamine metabolism
bit00740  Riboflavin metabolism
bit00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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