KEGG   PATHWAY: bpso00230
Entry
bpso00230                   Pathway                                
Name
Purine metabolism - Burkholderia pseudomallei A79A
Class
Metabolism; Nucleotide metabolism
Pathway map
bpso00230  Purine metabolism
bpso00230

Module
bpso_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bpso00230]
bpso_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bpso00230]
bpso_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bpso00230]
bpso_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bpso00230]
bpso_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bpso00230]
bpso_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bpso00230]
bpso_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bpso00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia pseudomallei A79A [GN:bpso]
Gene
X996_2990  NUDIX domain protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
X996_1494  phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III family protein [KO:K15778] [EC:5.4.2.8 5.4.2.2]
X996_153  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
X996_5855  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
X996_3054  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
X996_3290  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
X996_3088  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
X996_2120  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
X996_1340  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
X996_3402  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
X996_3403  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
X996_3404  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
X996_1227  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
X996_1259  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
X996_133  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
X996_2208  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
X996_2239  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
X996_1157  phosphoribosyl transferase domain protein [KO:K00760] [EC:2.4.2.8]
X996_2042  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
X996_2216  nucleoside diphosphate kinase family protein [KO:K00940] [EC:2.7.4.6]
X996_1585  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
X996_1432  xdhA; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
X996_1433  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
X996_679  peptidase C26 family protein [KO:K01951] [EC:6.3.5.2]
X996_2044  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
X996_1615  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
X996_1588  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
X996_1162  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
X996_5218  ribonucleotide reductase, barrel domain protein [KO:K00525] [EC:1.17.4.1]
X996_4622  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
X996_1163  ribonucleotide reductase, small chain family protein [KO:K00526] [EC:1.17.4.1]
X996_1809  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
X996_953  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
X996_1590  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
X996_2837  ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
X996_2669  RelA/SpoT family protein [KO:K00951] [EC:2.7.6.5]
X996_3470  response regulator [KO:K01768] [EC:4.6.1.1]
X996_2230  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
X996_1167  pfkB carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
X996_5763  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
X996_1617  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
X996_278  cpdB; 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
X996_3326  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
X996_2912  calcineurin-like phosphoesterase family protein [KO:K03651] [EC:3.1.4.53]
X996_1473  apaH; apaH [KO:K01525] [EC:3.6.1.41]
X996_2376  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
X996_1816  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
X996_1934  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
X996_5607  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
X996_3240  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
X996_3241  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
X996_1950  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
X996_2063  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
X996_2059  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
X996_2057  asp/Glu/Hydantoin racemase family protein [KO:K16841] [EC:5.1.99.3]
X996_2388  amidohydrolase family protein [KO:K01466] [EC:3.5.2.5]
X996_2058  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
X996_1210  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
X996_2060  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
X996_1211  ureidoglycolate hydrolase family protein [KO:K01483] [EC:4.3.2.3]
X996_2061  ureidoglycolate hydrolase family protein [KO:K01483] [EC:4.3.2.3]
X996_3973  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
X996_5384  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
X996_1501  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
X996_1502  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
X996_1503  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
X996_2458  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bpso00030  Pentose phosphate pathway
bpso00220  Arginine biosynthesis
bpso00250  Alanine, aspartate and glutamate metabolism
bpso00260  Glycine, serine and threonine metabolism
bpso00340  Histidine metabolism
bpso00630  Glyoxylate and dicarboxylate metabolism
bpso00730  Thiamine metabolism
bpso00740  Riboflavin metabolism
bpso00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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