KEGG   PATHWAY: bsi00230
Entry
bsi00230                    Pathway                                
Name
Purine metabolism - Brucella suis 1330
Class
Metabolism; Nucleotide metabolism
Pathway map
bsi00230  Purine metabolism
bsi00230

Module
bsi_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bsi00230]
bsi_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bsi00230]
bsi_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bsi00230]
bsi_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bsi00230]
bsi_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bsi00230]
bsi_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bsi00230]
bsi_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bsi00230]
Other DBs
GO: 0006163 0042278
Organism
Brucella suis 1330 [GN:bsi]
Gene
BS1330_I0058  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BS1330_I1527  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BS1330_I0447  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BS1330_I0415  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BS1330_I0705  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BS1330_I0833  purL; phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
BS1330_I0837  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
BS1330_I0836  purQ; phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BS1330_I0706  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
BS1330_I1739  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
BS1330_I1738  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BS1330_I0838  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BS1330_I0845  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BS1330_I1810  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BS1330_I1534  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BS1330_I0882  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BS1330_I1524  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BS1330_I1979  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BS1330_II0349  guaB; inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BS1330_I0690  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BS1330_I0175  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BS1330_I1042  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
BS1330_I0350  xanthine dehydrogenase, putative [KO:K13481] [EC:1.17.1.4]
BS1330_I0351  xanthine dehydrogenase, putative [KO:K13482] [EC:1.17.1.4]
BS1330_II0358  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
BS1330_I0355  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BS1330_I0465  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BS1330_II0313  nrdE; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BS1330_I1039  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BS1330_II0314  nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BS1330_I0872  dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
BS1330_I0662  hypothetical protein [KO:K06952] [EC:3.1.3.89]
BS1330_I0648  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BS1330_I0745  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BS1330_II0678  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BS1330_I1677  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BS1330_I0619  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BS1330_II0647  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
BS1330_I1716  hypothetical protein [KO:K09769] [EC:3.1.4.16]
BS1330_I0720  adenylate kinase, putative [KO:K00939] [EC:2.7.4.3]
BS1330_I1208  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BS1330_I1063  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
BS1330_I0194  cysNC; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein [KO:K00955] [EC:2.7.7.4 2.7.1.25]
BS1330_I0193  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
BS1330_I0509  hypothetical protein [KO:K07127] [EC:3.5.2.17]
BS1330_I0348  hypothetical protein [KO:K16842] [EC:3.5.2.5]
BS1330_I0347  hypothetical protein [KO:K14977] [EC:3.5.3.26]
BS1330_I0508  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BS1330_I1353  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BS1330_I0271  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BS1330_I1352  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
BS1330_I0270  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
BS1330_I1351  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
BS1330_I0269  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bsi00030  Pentose phosphate pathway
bsi00220  Arginine biosynthesis
bsi00250  Alanine, aspartate and glutamate metabolism
bsi00260  Glycine, serine and threonine metabolism
bsi00340  Histidine metabolism
bsi00630  Glyoxylate and dicarboxylate metabolism
bsi00730  Thiamine metabolism
bsi00740  Riboflavin metabolism
bsi00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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