KEGG   PATHWAY: bub00230
Entry
bub00230                    Pathway                                
Name
Purine metabolism - Burkholderia ubonensis
Class
Metabolism; Nucleotide metabolism
Pathway map
bub00230  Purine metabolism
bub00230

Module
bub_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bub00230]
bub_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bub00230]
bub_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bub00230]
bub_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bub00230]
bub_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bub00230]
bub_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bub00230]
bub_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bub00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia ubonensis [GN:bub]
Gene
BW23_2628  NUDIX domain protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BW23_833  phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III family protein [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BW23_2082  prs; ribose-phosphate diphosphokinase family protein [KO:K00948] [EC:2.7.6.1]
BW23_4727  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BW23_2566  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BW23_2376  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BW23_2543  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BW23_3077  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BW23_978  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BW23_2271  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
BW23_2270  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BW23_2269  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BW23_1069  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BW23_1045  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BW23_2101  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BW23_3162  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BW23_5867  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BW23_5375  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
BW23_3193  multi-copper polyphenol oxidoreductase laccase family protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BW23_1145  phosphoribosyl transferase domain protein [KO:K00760] [EC:2.4.2.8]
BW23_3004  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BW23_3170  nucleoside diphosphate kinase family protein [KO:K00940] [EC:2.7.4.6]
BW23_745  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BW23_905  xdhA; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
BW23_904  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BW23_3006  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
BW23_6266  glutamine amidotransferase class-I family protein [KO:K01951] [EC:6.3.5.2]
BW23_1638  peptidase C26 family protein [KO:K01951] [EC:6.3.5.2]
BW23_715  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BW23_742  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BW23_1140  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
BW23_5200  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BW23_1139  ribonucleotide reductase, small chain family protein [KO:K00526] [EC:1.17.4.1]
BW23_1355  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
BW23_740  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BW23_6337  mesh1; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BW23_432  ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BW23_273  RelA/SpoT family protein [KO:K00951] [EC:2.7.6.5]
BW23_2521  hypothetical protein [KO:K07816] [EC:2.7.6.5]
BW23_4655  2Fe-2S iron-sulfur cluster binding domain protein [KO:K01768] [EC:4.6.1.1]
BW23_6350  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BW23_3184  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BW23_1136  pfkB carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
BW23_4636  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BW23_714  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BW23_1984  hypothetical protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BW23_2338  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BW23_503  calcineurin-like phosphoesterase family protein [KO:K03651] [EC:3.1.4.53]
BW23_5719  ATP adenylyltransferase family protein [KO:K00988] [EC:2.7.7.5 2.7.7.53]
BW23_870  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
BW23_2744  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
BW23_2411  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
BW23_2410  phosphoadenosine phosphosulfate reductase family protein [KO:K00957] [EC:2.7.7.4]
BW23_3029  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BW23_3024  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
BW23_3022  asp/Glu/Hydantoin racemase family protein [KO:K16841] [EC:5.1.99.3]
BW23_3023  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
BW23_3025  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BW23_1088  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BW23_3827  hypothetical protein [KO:K14977] [EC:3.5.3.26]
BW23_3026  ureidoglycolate hydrolase family protein [KO:K01483] [EC:4.3.2.3]
BW23_1087  ureidoglycolate hydrolase family protein [KO:K01483] [EC:4.3.2.3]
BW23_3904  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
BW23_826  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BW23_825  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BW23_824  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BW23_3539  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bub00030  Pentose phosphate pathway
bub00220  Arginine biosynthesis
bub00250  Alanine, aspartate and glutamate metabolism
bub00260  Glycine, serine and threonine metabolism
bub00340  Histidine metabolism
bub00630  Glyoxylate and dicarboxylate metabolism
bub00730  Thiamine metabolism
bub00740  Riboflavin metabolism
bub00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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