KEGG   PATHWAY: bub00630
Entry
bub00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia ubonensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
bub00630  Glyoxylate and dicarboxylate metabolism
bub00630

Module
bub_M00012  Glyoxylate cycle [PATH:bub00630]
bub_M00621  Glycine cleavage system [PATH:bub00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia ubonensis [GN:bub]
Gene
BW23_5312  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BW23_2950  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BW23_5613  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BW23_2675  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BW23_6237  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BW23_3395  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BW23_403  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BW23_3992  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
BW23_2946  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BW23_4688  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BW23_2352  merR regulatory family protein [KO:K01647] [EC:2.3.3.1]
BW23_4695  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BW23_3901  2-methylcitrate synthase/citrate synthase II family protein [KO:K01659] [EC:2.3.3.5]
BW23_4684  acnA; aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
BW23_4277  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
BW23_3087  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW23_1953  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW23_3195  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW23_3204  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW23_6235  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW23_6256  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW23_2120  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW23_6081  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
BW23_3196  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BW23_2121  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
BW23_1004  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
BW23_1005  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
BW23_1006  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
BW23_492  catalase family protein [KO:K03781] [EC:1.11.1.6]
BW23_1702  catalase family protein [KO:K03781] [EC:1.11.1.6]
BW23_5961  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BW23_1925  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BW23_627  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BW23_3253  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BW23_5699  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
BW23_618  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
BW23_3311  haloacid dehalogenase-like hydrolase family protein [KO:K01091] [EC:3.1.3.18]
BW23_1214  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BW23_3534  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BW23_1892  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BW23_2742  glutamine synthetase, beta-Grasp domain protein [KO:K01915] [EC:6.3.1.2]
BW23_2759  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BW23_935  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
BW23_3480  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
BW23_1570  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BW23_1568  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
BW23_237  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BW23_2781  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BW23_5911  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BW23_1569  gcvH; glycine cleavage system H protein [KO:K02437]
BW23_3114  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BW23_3113  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BW23_3112  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BW23_3064  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BW23_4029  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BW23_1074  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BW23_5410  bicupin, oxalate decarboxylase family protein [KO:K01569] [EC:4.1.1.2]
BW23_704  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
BW23_4745  molybdopterin oxidoreductase Fe4S4 domain protein [KO:K00123] [EC:1.17.1.9]
BW23_4746  fdnG; formate dehydrogenase-N alpha subunit [KO:K00123] [EC:1.17.1.9]
BW23_703  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BW23_4747  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
BW23_702  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
BW23_4748  formate dehydrogenase, gamma subunit [KO:K00127]
BW23_701  thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]
BW23_4042  alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]
BW23_2307  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BW23_2104  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BW23_3469  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BW23_2740  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bub00010  Glycolysis / Gluconeogenesis
bub00020  Citrate cycle (TCA cycle)
bub00030  Pentose phosphate pathway
bub00053  Ascorbate and aldarate metabolism
bub00071  Fatty acid degradation
bub00230  Purine metabolism
bub00250  Alanine, aspartate and glutamate metabolism
bub00260  Glycine, serine and threonine metabolism
bub00620  Pyruvate metabolism
bub00710  Carbon fixation by Calvin cycle
bub00750  Vitamin B6 metabolism
bub00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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