KEGG   PATHWAY: cabi00330
Entry
cabi00330                   Pathway                                
Name
Arginine and proline metabolism - Chelonoidis abingdonii (Abingdon island giant tortoise)
Class
Metabolism; Amino acid metabolism
Pathway map
cabi00330  Arginine and proline metabolism
cabi00330

Module
cabi_M00015  Proline biosynthesis, glutamate => proline [PATH:cabi00330]
cabi_M00047  Creatine pathway [PATH:cabi00330]
cabi_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:cabi00330]
cabi_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:cabi00330]
cabi_M00970  Proline degradation, proline => glutamate [PATH:cabi00330]
cabi_M00972  Proline metabolism [PATH:cabi00330]
Other DBs
GO: 0006525 0006560
Organism
Chelonoidis abingdonii (Abingdon island giant tortoise) [GN:cabi]
Gene
116814728  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
116815624  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
116815836  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
116816340  SATL1; spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X1 [KO:K00657] [EC:2.3.1.57]
116816552  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
116816736  SMOX; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
116817846  [KO:K00318] [EC:1.5.5.2]
116818343  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
116819659  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
116819716  CNDP2; cytosolic non-specific dipeptidase isoform X1 [KO:K08660] [EC:3.4.13.18]
116819721  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
116821489  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
116821924  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
116822802  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
116823132  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
116824205  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
116824354  AGMAT; agmatinase, mitochondrial [KO:K27001]
116825272  P4HA3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
116825316  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
116825677  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
116825945  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
116826185  PRODH2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
116826256  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
116826985  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
116827924  ALDH3A2; aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
116828310  [KO:K00657] [EC:2.3.1.57]
116828326  [KO:K00657] [EC:2.3.1.57]
116828575  [KO:K14454] [EC:2.6.1.1]
116828991  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
116830245  [KO:K01581] [EC:4.1.1.17]
116830926  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
116831036  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
116832795  [KO:K01581] [EC:4.1.1.17]
116832860  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
116833078  [KO:K08660] [EC:3.4.13.18]
116833424  CARNS1; carnosine synthase 1 [KO:K14755] [EC:6.3.2.11]
116833977  [KO:K00274] [EC:1.4.3.4]
116833984  [KO:K00274] [EC:1.4.3.4]
116834210  [KO:K13242] [EC:1.14.13.39]
116834416  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
116835318  CKM; LOW QUALITY PROTEIN: creatine kinase M-type [KO:K27382]
116835602  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
116836436  NOS1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
116836705  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
116836821  ARG1; arginase-1 isoform X1 [KO:K01476] [EC:3.5.3.1]
116836840  LAP3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
116838088  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
116839453  DAO; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
116839902  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
116839990  [KO:K05604] [EC:3.4.13.20]
116840049  ALDH16A1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
cabi00020  Citrate cycle (TCA cycle)
cabi00220  Arginine biosynthesis
cabi00250  Alanine, aspartate and glutamate metabolism
cabi00260  Glycine, serine and threonine metabolism
cabi00270  Cysteine and methionine metabolism
cabi00310  Lysine degradation
cabi00410  beta-Alanine metabolism
cabi00470  D-Amino acid metabolism
cabi00480  Glutathione metabolism
cabi00630  Glyoxylate and dicarboxylate metabolism
cabi00650  Butanoate metabolism
cabi00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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