KEGG   PATHWAY: caty00330
Entry
caty00330                   Pathway                                
Name
Arginine and proline metabolism - Cercocebus atys (sooty mangabey)
Class
Metabolism; Amino acid metabolism
Pathway map
caty00330  Arginine and proline metabolism
caty00330

Module
caty_M00015  Proline biosynthesis, glutamate => proline [PATH:caty00330]
caty_M00047  Creatine pathway [PATH:caty00330]
caty_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:caty00330]
caty_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:caty00330]
caty_M00970  Proline degradation, proline => glutamate [PATH:caty00330]
caty_M00972  Proline metabolism [PATH:caty00330]
Other DBs
GO: 0006525 0006560
Organism
Cercocebus atys (sooty mangabey) [GN:caty]
Gene
105573170  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
105573229  DAO; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
105574619  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
105574631  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
105576456  [KO:K01581] [EC:4.1.1.17]
105576935  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X1 [KO:K00286] [EC:1.5.1.2]
105577355  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
105578012  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
105578193  PRODH2; probable proline dehydrogenase 2 isoform X1 [KO:K11394] [EC:1.5.5.3]
105578635  ODC1; ornithine decarboxylase isoform X1 [KO:K01581] [EC:4.1.1.17]
105578755  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
105579019  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
105580872  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
105581210  PYCRL; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
105581372  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
105581757  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
105581795  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
105581817  GOT1; aspartate aminotransferase, cytoplasmic isoform X1 [KO:K14454] [EC:2.6.1.1]
105582126  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
105582256  SAT2; diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
105582865  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
105584732  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
105584734  NOS3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
105586695  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
105587672  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
105588183  GATM; glycine amidinotransferase, mitochondrial isoform X1 [KO:K00613] [EC:2.1.4.1]
105588579  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
105590551  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
105590553  [KO:K00274] [EC:1.4.3.4]
105590786  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
105591502  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
105591715  GAMT; guanidinoacetate N-methyltransferase isoform X1 [KO:K00542] [EC:2.1.1.2]
105592744  NOS1; LOW QUALITY PROTEIN: nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
105593068  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
105593727  ALDH3A2; fatty aldehyde dehydrogenase isoform X1 [KO:K00128] [EC:1.2.1.3]
105594804  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
105595100  [KO:K01581] [EC:4.1.1.17]
105595142  CKM; creatine kinase M-type [KO:K27382]
105595288  ALDH16A1; aldehyde dehydrogenase family 16 member A1 isoform X1 [KO:K00128] [EC:1.2.1.3]
105596473  CNDP2; cytosolic non-specific dipeptidase isoform X1 [KO:K08660] [EC:3.4.13.18]
105596474  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
105596743  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
105597316  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
105597650  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1 [KO:K00294] [EC:1.2.1.88]
105598281  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
105599138  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
105599421  AGMAT; agmatinase, mitochondrial [KO:K27001]
105599693  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
105599731  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
105600460  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
105601312  PRODH; proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
caty00020  Citrate cycle (TCA cycle)
caty00220  Arginine biosynthesis
caty00250  Alanine, aspartate and glutamate metabolism
caty00260  Glycine, serine and threonine metabolism
caty00270  Cysteine and methionine metabolism
caty00310  Lysine degradation
caty00410  beta-Alanine metabolism
caty00470  D-Amino acid metabolism
caty00480  Glutathione metabolism
caty00630  Glyoxylate and dicarboxylate metabolism
caty00650  Butanoate metabolism
caty00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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