KEGG   PATHWAY: cbai04612
Entry
cbai04612                   Pathway                                
Name
Antigen processing and presentation - Camelus bactrianus (Bactrian camel)
Class
Organismal Systems; Immune system
Pathway map
cbai04612  Antigen processing and presentation
cbai04612

Other DBs
GO: 0019885 0019886 0042591
Organism
Camelus bactrianus (Bactrian camel) [GN:cbai]
Gene
105061640  [KO:K06751]
105062008  CANX; calnexin [KO:K08054]
105062207  KLRD1; natural killer cells antigen CD94 [KO:K06516]
105062210  [KO:K06541]
105064223  TAPBP; tapasin [KO:K08058]
105064235  [KO:K06752]
105064238  [KO:K06752]
105064239  [KO:K06752]
105064241  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
105064243  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
105064245  [KO:K06752]
105064246  [KO:K06752]
105064247  [KO:K06752]
105064248  [KO:K06752]
105064249  [KO:K06752]
105064250  [KO:K06752]
105064272  [KO:K06752]
105064273  [KO:K06752]
105064275  [KO:K06752]
105064276  [KO:K06752]
105065248  [KO:K06751]
105066308  RFXAP; regulatory factor X-associated protein [KO:K08063]
105068023  HSPA6; heat shock 70 kDa protein 6 [KO:K03283]
105068326  CALR; calreticulin [KO:K08057]
105068799  PSME1; proteasome activator complex subunit 1 [KO:K06696]
105068800  PSME2; proteasome activator complex subunit 2 [KO:K06697]
105069906  HSPA5; 78 kDa glucose-regulated protein [KO:K09490] [EC:3.6.4.10]
105071091  CD4; T-cell surface glycoprotein CD4 [KO:K06454]
105071107  TAPBPL; tapasin-related protein isoform X1 [KO:K28445]
105071695  [KO:K06752]
105071715  RFX5; LOW QUALITY PROTEIN: DNA-binding protein RFX5 [KO:K08061]
105071741  CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
105072260  CD8A; LOW QUALITY PROTEIN: T-cell surface glycoprotein CD8 alpha chain [KO:K06458]
105072261  CD8B; T-cell surface glycoprotein CD8 beta chain [KO:K06459]
105072753  NFYC; nuclear transcription factor Y subunit gamma isoform X1 [KO:K08066]
105072963  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
105073236  CIITA; LOW QUALITY PROTEIN: MHC class II transactivator [KO:K08060] [EC:2.7.11.1]
105074047  [KO:K03283]
105074048  HSPA1B; LOW QUALITY PROTEIN: heat shock 70 kDa protein 1A/1B [KO:K03283]
105074049  HSPA1L; heat shock 70 kDa protein 1-like [KO:K03283]
105074074  TNF; tumor necrosis factor [KO:K03156]
105074080  [KO:K06751]
105074082  [KO:K06751]
105074083  [KO:K06751]
105074084  [KO:K06751]
105074117  [KO:K06751]
105074299  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
105074488  [KO:K07980]
105074668  HSPA2; heat shock-related 70 kDa protein 2 [KO:K26598]
105076963  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
105076977  B2M; beta-2-microglobulin [KO:K08055]
105078638  HSPA8; LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein [KO:K03283]
105078803  CTSL; cathepsin L1 [KO:K01365] [EC:3.4.22.15]
105078823  CTSV; cathepsin L2 [KO:K01365] [EC:3.4.22.15]
105079874  LGMN; legumain [KO:K01369] [EC:3.4.22.34]
105079942  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
105080092  PSME3; proteasome activator complex subunit 3 [KO:K06698]
105081302  NFYB; nuclear transcription factor Y subunit beta isoform X1 [KO:K08065]
105081344  IFNG; interferon gamma [KO:K04687]
105082116  HSPA4; heat shock 70 kDa protein 4 [KO:K09489]
105082599  RFXANK; DNA-binding protein RFXANK isoform X1 [KO:K08062]
105082680  IFI30; gamma-interferon-inducible lysosomal thiol reductase [KO:K08059]
105083368  CTSB; LOW QUALITY PROTEIN: cathepsin B [KO:K01363] [EC:3.4.22.1]
105083758  NFYA; nuclear transcription factor Y subunit alpha isoform X1 [KO:K08064]
105083823  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
Reference
PMID:15771591
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
DOI:10.1146/annurev.immunol.22.012703.104538
Reference
PMID:15814328
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
DOI:10.1532/IJH97.04200
Reference
PMID:11905820
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
DOI:10.1038/35100512
Reference
PMID:15304636
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
DOI:10.1152/physiol.00002.2004
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:12776207
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
DOI:10.1038/nri1110
Reference
PMID:12974477
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
DOI:10.1038/nri1149
Reference
PMID:15224093
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
DOI:10.1038/ni1082
Reference
PMID:16181333
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
DOI:10.1111/j.0105-2896.2005.00316.x
Reference
PMID:15653312
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
DOI:10.1016/j.coi.2004.11.008
Reference
PMID:11244040
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
DOI:10.1146/annurev.immunol.19.1.331
Reference
PMID:15745856
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
DOI:10.1016/j.it.2005.01.005
Reference
PMID:15224094
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
DOI:10.1038/ni1088
Reference
PMID:15653315
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
DOI:10.1016/j.coi.2004.12.004
Reference
PMID:20010787
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
DOI:10.1038/nri2687
Related
pathway
cbai03050  Proteasome
cbai04650  Natural killer cell mediated cytotoxicity
cbai04660  T cell receptor signaling pathway
KO pathway
ko04612   

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