KEGG   PATHWAY: cbrc00564
Entry
cbrc00564                   Pathway                                
Name
Glycerophospholipid metabolism - Corvus brachyrhynchos (American crow)
Class
Metabolism; Lipid metabolism
Pathway map
cbrc00564  Glycerophospholipid metabolism
cbrc00564

Module
cbrc_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:cbrc00564]
cbrc_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:cbrc00564]
cbrc_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:cbrc00564]
Other DBs
GO: 0006650
Organism
Corvus brachyrhynchos (American crow) [GN:cbrc]
Gene
103611729  PCYT1B; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
103611952  [KO:K00901] [EC:2.7.1.107]
103612192  PLD4; phospholipase D4 isoform X1 [KO:K16860] [EC:3.1.4.4]
103612316  DGKB; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
103612680  LCLAT1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
103612804  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
103613008  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
103613154  PCYT2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
103613191  MBOAT1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
103613218  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
103613556  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
103613883  PLA1A; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
103613959  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
103614027  [KO:K01047] [EC:3.1.1.4]
103614149  [KO:K00006] [EC:1.1.1.8]
103614186  PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X2 [KO:K01613] [EC:4.1.1.65]
103614563  PTDSS2; phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
103614635  PLPP5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
103614739  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
103614840  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
103615104  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
103615135  DGKH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
103615259  SGMS1; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
103615396  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
103615496  PLA2G10; group 10 secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
103616176  [KO:K01047] [EC:3.1.1.4]
103616197  [KO:K01047] [EC:3.1.1.4]
103616198  [KO:K01047] [EC:3.1.1.4]
103616271  GPAM; LOW QUALITY PROTEIN: glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
103616424  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
103616479  CEPT1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
103616779  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
103616832  LYPLA2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
103616991  [KO:K13509] [EC:2.3.1.51]
103617036  LPIN3; LOW QUALITY PROTEIN: phosphatidate phosphatase LPIN3 [KO:K15728] [EC:3.1.3.4]
103617140  PLA2G4A; cytosolic phospholipase A2 isoform X2 [KO:K16342] [EC:3.1.1.4]
103617209  PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
103617290  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
103617327  SGMS2; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
103617331  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
103617396  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
103618087  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
103618332  [KO:K13509] [EC:2.3.1.51]
103618422  LPIN2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
103619044  LPCAT1; lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
103619097  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
103619181  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
103619210  CHKB; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
103619566  DGKI; LOW QUALITY PROTEIN: diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
103619570  CHPT1; cholinephosphotransferase 1 isoform X1 [KO:K00994] [EC:2.7.8.2]
103619673  [KO:K00006] [EC:1.1.1.8]
103619778  PNPLA7; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
103619892  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
103620140  LCAT; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
103620301  PLA2G15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
103620306  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
103620767  [KO:K16342] [EC:3.1.1.4]
103620770  [KO:K16342] [EC:3.1.1.4]
103620771  [KO:K16342] [EC:3.1.1.4]
103620773  [KO:K16342] [EC:3.1.1.4]
103620774  [KO:K16342] [EC:3.1.1.4]
103620903  CHKA; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
103620927  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
103620948  [KO:K16342] [EC:3.1.1.4]
103620949  [KO:K16342] [EC:3.1.1.4]
103620951  [KO:K16342] [EC:3.1.1.4]
103620952  PLA2G4F; cytosolic phospholipase A2 zeta isoform X1 [KO:K16342] [EC:3.1.1.4]
103621067  [KO:K14676] [EC:3.1.1.5]
103621557  PROCA1; protein PROCA1 [KO:K01047] [EC:3.1.1.4]
103622162  PLPP2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
103622181  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
103622343  [KO:K13506] [EC:2.3.1.15]
103622344  [KO:K13506] [EC:2.3.1.15]
103622399  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
103622627  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
103622645  PLA2G1B; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
103622755  PLB1; phospholipase B1, membrane-associated isoform X2 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
103622785  LPIN1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
103622847  MBOAT2; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
103623236  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
103623513  EPT1; ethanolaminephosphotransferase 1 isoform X2 [KO:K00993] [EC:2.7.8.1]
103623672  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
103623698  SAMD8; sphingomyelin synthase-related protein 1 [KO:K22697] [EC:3.1.4.62]
103624015  PLPP4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
103624036  PLPP1; phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
103624120  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
103624175  GNPAT; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
103625005  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X2 [KO:K18695] [EC:3.1.4.2]
103625008  CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
103625010  DGKD; diacylglycerol kinase delta isoform X3 [KO:K00901] [EC:2.7.1.107]
103625086  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
103625155  PCYT1A; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
103625381  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
103625483  [KO:K00993] [EC:2.7.8.1]
103625497  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
cbrc00010  Glycolysis / Gluconeogenesis
cbrc00260  Glycine, serine and threonine metabolism
cbrc00561  Glycerolipid metabolism
cbrc00562  Inositol phosphate metabolism
cbrc00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
cbrc00565  Ether lipid metabolism
cbrc00620  Pyruvate metabolism
KO pathway
ko00564   

DBGET integrated database retrieval system