KEGG   PATHWAY: cic04148
Entry
cic04148                    Pathway                                
Name
Efferocytosis - Citrus x clementina (clementine)
Class
Cellular Processes; Transport and catabolism
Pathway map
cic04148  Efferocytosis
cic04148

Organism
Citrus x clementina (clementine) [GN:cic]
Gene
CICLE_v10000070mg  [KO:K17398] [EC:2.1.1.37]
CICLE_v10000142mg  [KO:K05853] [EC:7.2.2.10]
CICLE_v10001298mg  [KO:K08057]
CICLE_v10002522mg  [KO:K07897]
CICLE_v10002551mg  [KO:K04392]
CICLE_v10005291mg  [KO:K26935]
CICLE_v10005587mg  [KO:K00411] [EC:7.1.1.8]
CICLE_v10008771mg  [KO:K04368] [EC:2.7.12.2]
CICLE_v10009470mg  [KO:K04392]
CICLE_v10009505mg  [KO:K07897]
CICLE_v10009547mg  [KO:K07887]
CICLE_v10010927mg  [KO:K14802] [EC:7.6.2.1]
CICLE_v10011848mg  [KO:K08057]
CICLE_v10011933mg  [KO:K23678]
CICLE_v10013434mg  [KO:K26935]
CICLE_v10014078mg  [KO:K14802] [EC:7.6.2.1]
CICLE_v10014143mg  [KO:K20177]
CICLE_v10014147mg  [KO:K20181]
CICLE_v10015071mg  [KO:K04718] [EC:2.7.1.91]
CICLE_v10015400mg  [KO:K01052] [EC:3.1.1.13]
CICLE_v10015828mg  [KO:K26935]
CICLE_v10016185mg  [KO:K04459] [EC:3.1.3.16 3.1.3.48]
CICLE_v10016224mg  [KO:K00411] [EC:7.1.1.8]
CICLE_v10016769mg  [KO:K07887]
CICLE_v10016797mg  [KO:K04392]
CICLE_v10016801mg  [KO:K04392]
CICLE_v10017979mg  [KO:K01052] [EC:3.1.1.13]
CICLE_v10018207mg  [KO:K20179]
CICLE_v10018296mg  [KO:K01052] [EC:3.1.1.13]
CICLE_v10018449mg  [KO:K20178]
CICLE_v10020253mg  [KO:K01581] [EC:4.1.1.17]
CICLE_v10020358mg  [KO:K08057]
CICLE_v10021006mg  [KO:K01476] [EC:3.5.3.1]
CICLE_v10022245mg  [KO:K04392]
CICLE_v10023530mg  [KO:K04392]
CICLE_v10024797mg  [KO:K20183]
CICLE_v10025820mg  [KO:K23678]
CICLE_v10026484mg  [KO:K07897]
CICLE_v10026539mg  [KO:K04392]
CICLE_v10027073mg  [KO:K07887]
CICLE_v10027764mg  [KO:K20184]
CICLE_v10028684mg  [KO:K04371] [EC:2.7.11.24]
CICLE_v10029292mg  [KO:K07897]
CICLE_v10029311mg  [KO:K04392]
CICLE_v10030537mg  [KO:K14802] [EC:7.6.2.1]
CICLE_v10030701mg  [KO:K20180]
CICLE_v100310721m  [KO:K20182]
CICLE_v10031824mg  [KO:K01581] [EC:4.1.1.17]
CICLE_v10032775mg  [KO:K07887]
Compound
C00002  ATP
C00003  NAD+
C00019  S-Adenosyl-L-methionine
C00031  D-Glucose
C00062  L-Arginine
C00073  L-Methionine
C00075  UTP
C00077  L-Ornithine
C00134  Putrescine
C00162  Fatty acid
C00186  (S)-Lactate
C00187  Cholesterol
C00584  Prostaglandin E2
C02530  Cholesterol ester
C02737  Phosphatidylserine
C04230  1-Acyl-sn-glycero-3-phosphocholine
C06124  Sphingosine 1-phosphate
C06314  Lipoxin A4
C15519  25-Hydroxycholesterol
C15610  Cholest-5-ene-3beta,26-diol
C18178  Resolvin D1
Reference
PMID:31822793
  Authors
Doran AC, Yurdagul A Jr, Tabas I
  Title
Efferocytosis in health and disease.
  Journal
Nat Rev Immunol 20:254-267 (2020)
DOI:10.1038/s41577-019-0240-6
Reference
PMID:36028471
  Authors
Zhang J, Ding W, Zhao M, Liu J, Xu Y, Wan J, Wang M
  Title
Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease.
  Journal
Br J Pharmacol 179:5151-5171 (2022)
DOI:10.1111/bph.15939
Reference
PMID:30165442
  Authors
Kawano M, Nagata S
  Title
Efferocytosis and autoimmune disease.
  Journal
Int Immunol 30:551-558 (2018)
DOI:10.1093/intimm/dxy055
Reference
PMID:35650427
  Authors
Mehrotra P, Ravichandran KS
  Title
Drugging the efferocytosis process: concepts and opportunities.
  Journal
Nat Rev Drug Discov 21:601-620 (2022)
DOI:10.1038/s41573-022-00470-y
Reference
PMID:28496201
  Authors
Park SY, Kim IS
  Title
Engulfment signals and the phagocytic machinery for apoptotic cell clearance.
  Journal
Exp Mol Med 49:e331 (2017)
DOI:10.1038/emm.2017.52
Reference
PMID:28137963
  Authors
Kojima Y, Weissman IL, Leeper NJ
  Title
The Role of Efferocytosis in Atherosclerosis.
  Journal
Circulation 135:476-489 (2017)
DOI:10.1161/CIRCULATIONAHA.116.025684
Related
pathway
cic00010  Glycolysis / Gluconeogenesis
cic04145  Phagosome
KO pathway
ko04148   

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