KEGG   PATHWAY: cmao00330
Entry
cmao00330                   Pathway                                
Name
Arginine and proline metabolism - Colossoma macropomum (tambaqui)
Class
Metabolism; Amino acid metabolism
Pathway map
cmao00330  Arginine and proline metabolism
cmao00330

Module
cmao_M00015  Proline biosynthesis, glutamate => proline [PATH:cmao00330]
cmao_M00047  Creatine pathway [PATH:cmao00330]
cmao_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:cmao00330]
cmao_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:cmao00330]
cmao_M00970  Proline degradation, proline => glutamate [PATH:cmao00330]
cmao_M00972  Proline metabolism [PATH:cmao00330]
Other DBs
GO: 0006525 0006560
Organism
Colossoma macropomum (tambaqui) [GN:cmao]
Gene
118797084  zgc:152670; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
118798844  sat1b; diamine acetyltransferase 1b [KO:K00657] [EC:2.3.1.57]
118799345  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
118799361  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
118800928  aldh3a1; aldehyde dehydrogenase, dimeric NADP-preferring isoform X1 [KO:K00128] [EC:1.2.1.3]
118800943  aldh3a2a; aldehyde dehydrogenase family 3 member A2a [KO:K00128] [EC:1.2.1.3]
118801144  ckmb; creatine kinase, muscle b [KO:K27382]
118803992  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
118804005  [KO:K13241] [EC:1.14.13.39]
118804014  [KO:K13241] [EC:1.14.13.39]
118806188  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
118806805  ckmt1; creatine kinase, mitochondrial 1 [KO:K00933] [EC:2.7.3.2]
118808970  [KO:K00819] [EC:2.6.1.13]
118808971  [KO:K00819] [EC:2.6.1.13]
118808988  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
118809393  aldh18a1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
118809657  p4ha1a; prolyl 4-hydroxylase subunit alpha-1a isoform X1 [KO:K00472] [EC:1.14.11.2]
118809660  arg1; arginase-1 [KO:K01476] [EC:3.5.3.1]
118809756  prodh2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
118810363  ckba; creatine kinase, brain a [KO:K00933] [EC:2.7.3.2]
118810394  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
118811006  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
118813707  paox1; polyamine oxidase (exo-N4-amino) 1 isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
118813734  aldh9a1a.1; LOW QUALITY PROTEIN: 4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
118814046  got1l1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
118814494  ckma; creatine kinase, muscle a [KO:K27382]
118814950  sat2b; diamine acetyltransferase 2b isoform X1 [KO:K00657] [EC:2.3.1.57]
118814951  sat1a.2; diamine acetyltransferase 1a.2 [KO:K00657] [EC:2.3.1.57]
118815312  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
118815535  ckbb; creatine kinase, brain b [KO:K00933] [EC:2.7.3.2]
118815867  pycr3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
118816162  [KO:K18384] [EC:4.2.1.77]
118816587  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
118816631  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
118817343  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
118817391  mao; amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
118818188  got2a; glutamic-oxaloacetic transaminase 2a, mitochondrial [KO:K14455] [EC:2.6.1.1]
118818646  [KO:K27382]
118818792  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
118819181  pycr1b; pyrroline-5-carboxylate reductase 1b [KO:K00286] [EC:1.5.1.2]
118819672  aldh3a2b; aldehyde dehydrogenase family 3 member A2b [KO:K00128] [EC:1.2.1.3]
118819673  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
118819742  [KO:K00472] [EC:1.14.11.2]
118819809  prodha; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
118820356  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
118820971  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
118821123  aldh16a1; aldehyde dehydrogenase family 16 member A1 isoform X1 [KO:K00128] [EC:1.2.1.3]
118821495  pycr1a; pyrroline-5-carboxylate reductase 1a [KO:K00286] [EC:1.5.1.2]
118822162  agmat; agmatinase, mitochondrial [KO:K27001]
118822814  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
118823911  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
118824180  p4ha1b; prolyl 4-hydroxylase subunit alpha-1b isoform X1 [KO:K00472] [EC:1.14.11.2]
118824443  si:ch211-127i16.2; LOW QUALITY PROTEIN: amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
118824520  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
118824558  ckmt2a; creatine kinase, mitochondrial 2a (sarcomeric) [KO:K00933] [EC:2.7.3.2]
118825765  si:dkey-19b23.15; diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
118826290  aldh9a1b; 4-trimethylaminobutyraldehyde dehydrogenase B [KO:K00149] [EC:1.2.1.47 1.2.1.3]
118826850  [KO:K00128] [EC:1.2.1.3]
118826894  [KO:K00273] [EC:1.4.3.3]
118827114  ckmt2b; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
118827337  prodhb; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
118827487  nos1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
cmao00020  Citrate cycle (TCA cycle)
cmao00220  Arginine biosynthesis
cmao00250  Alanine, aspartate and glutamate metabolism
cmao00260  Glycine, serine and threonine metabolism
cmao00270  Cysteine and methionine metabolism
cmao00310  Lysine degradation
cmao00410  beta-Alanine metabolism
cmao00470  D-Amino acid metabolism
cmao00480  Glutathione metabolism
cmao00630  Glyoxylate and dicarboxylate metabolism
cmao00650  Butanoate metabolism
cmao00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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