KEGG   PATHWAY: cmk00330
Entry
cmk00330                    Pathway                                
Name
Arginine and proline metabolism - Callorhinchus milii (elephant shark)
Class
Metabolism; Amino acid metabolism
Pathway map
cmk00330  Arginine and proline metabolism
cmk00330

Module
cmk_M00015  Proline biosynthesis, glutamate => proline [PATH:cmk00330]
cmk_M00047  Creatine pathway [PATH:cmk00330]
cmk_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:cmk00330]
cmk_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:cmk00330]
Other DBs
GO: 0006525 0006560
Organism
Callorhinchus milii (elephant shark) [GN:cmk]
Gene
103186480  gatm; glycine amidinotransferase, mitochondrial isoform X1 [KO:K00613] [EC:2.1.4.1]
103181936  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
103175312  ckba; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
103188464  ckmt1b; creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
103178013  creatine kinase M-type isoform X1 [KO:K27382] [EC:2.7.3.2]
103180949  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
103181364  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
103189993  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
103178957  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
103179450  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
103181501  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
103189441  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
103186924  aldehyde dehydrogenase, dimeric NADP-preferring [KO:K00128] [EC:1.2.1.3]
103184053  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
103182361  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
103180031  aldh9a1a.1; 4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
103184951  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
103187601  diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
103183911  mao; amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
103177252  amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
103187649  agmat; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
103184386  nos1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
103183299  nos2b; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
103175210  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
103181791  arginase-1-like [KO:K01476] [EC:3.5.3.1]
103185443  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
103175576  pycr1a; pyrroline-5-carboxylate reductase 1a isoform X1 [KO:K00286] [EC:1.5.1.2]
103189972  aldh18a1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
103175807  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
103181221  p4ha1b; prolyl 4-hydroxylase subunit alpha-1b isoform X1 [KO:K00472] [EC:1.14.11.2]
103177143  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
103184118  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
103188918  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
103171659  got2a; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
103172525  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
103184038  dao; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
103178517  trans-L-3-hydroxyproline dehydratase [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
cmk00020  Citrate cycle (TCA cycle)
cmk00220  Arginine biosynthesis
cmk00250  Alanine, aspartate and glutamate metabolism
cmk00260  Glycine, serine and threonine metabolism
cmk00270  Cysteine and methionine metabolism
cmk00310  Lysine degradation
cmk00410  beta-Alanine metabolism
cmk00470  D-Amino acid metabolism
cmk00480  Glutathione metabolism
cmk00630  Glyoxylate and dicarboxylate metabolism
cmk00650  Butanoate metabolism
cmk00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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