KEGG   PATHWAY: cmk00310
Entry
cmk00310                    Pathway                                
Name
Lysine degradation - Callorhinchus milii (elephant shark)
Class
Metabolism; Amino acid metabolism
Pathway map
cmk00310  Lysine degradation
cmk00310

Other DBs
GO: 0006554
Organism
Callorhinchus milii (elephant shark) [GN:cmk]
Gene
103179368  aass; alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1 [KO:K14157] [EC:1.5.1.8 1.5.1.9]
103182361  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
103180238  aadat; kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [KO:K00825] [EC:2.6.1.7 2.6.1.39]
103187915  dhtkd1; LOW QUALITY PROTEIN: probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial [KO:K15791] [EC:1.2.4.-]
103188491  dlst; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [KO:K00658] [EC:2.3.1.61]
103189342  dldh; dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
103183149  trifunctional enzyme subunit alpha, mitochondrial [KO:K07515] [EC:4.2.1.17 1.1.1.211]
103182105  echs1; enoyl-CoA hydratase, mitochondrial [KO:K07511] [EC:4.2.1.17]
103182114  hadh; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [KO:K00022] [EC:1.1.1.35]
103178593  LOW QUALITY PROTEIN: acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
103186520  acat1; acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
103191217  acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
121848070  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
103186056  hykk; hydroxylysine kinase [KO:K18201] [EC:2.7.1.81]
103183728  phykpl; 5-phosphohydroxy-L-lysine phospho-lyase isoform X1 [KO:K18202] [EC:4.2.3.134]
103183351  pipox; peroxisomal sarcosine oxidase [KO:K00306] [EC:1.5.3.1 1.5.3.7]
103180809  camkmt; calmodulin-lysine N-methyltransferase isoform X1 [KO:K18826] [EC:2.1.1.60]
103189435  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C [KO:K09188] [EC:2.1.1.354]
103176975  kmt2e; inactive histone-lysine N-methyltransferase 2E isoform X1 [KO:K09189] [EC:2.1.1.354]
103181297  setd7; histone-lysine N-methyltransferase SETD7 [KO:K11431] [EC:2.1.1.364]
103181513  histone-lysine N-methyltransferase Smyd1 isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
103186165  N-lysine methyltransferase SMYD2 isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
103181738  smyd3; histone-lysine N-methyltransferase SMYD3 isoform X2 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
103173106  histone-lysine N-methyltransferase SUV39H2 isoform X1 [KO:K11419] [EC:2.1.1.355]
103180404  histone-lysine N-methyltransferase EHMT1 isoform X1 [KO:K11420] [EC:2.1.1.355]
103181338  prdm2a; PR domain zinc finger protein 2 [KO:K11432] [EC:2.1.1.355]
103187005  ezh2; histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
103174199  setmar; histone-lysine N-methyltransferase SETMAR [KO:K11433] [EC:2.1.1.357]
103189717  histone-lysine N-methyltransferase, H3 lysine-36 specific [KO:K15588] [EC:2.1.1.357]
103183116  nsd2; histone-lysine N-methyltransferase NSD2 isoform X1 [KO:K11424] [EC:2.1.1.357]
103190419  nsd3; histone-lysine N-methyltransferase NSD3 isoform X1 [KO:K11425] [EC:2.1.1.370 2.1.1.371]
103190896  setd2; histone-lysine N-methyltransferase SETD2 isoform X3 [KO:K11423] [EC:2.1.1.359]
103181918  dot1l; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 [KO:K11427] [EC:2.1.1.360]
103188010  N-lysine methyltransferase KMT5A isoform X1 [KO:K11428] [EC:2.1.1.361]
103182382  prdm6; putative histone-lysine N-methyltransferase PRDM6 [KO:K20795] [EC:2.1.1.361]
103174937  kmt5b; histone-lysine N-methyltransferase KMT5B [KO:K11429] [EC:2.1.1.362]
103189530  LOW QUALITY PROTEIN: uncharacterized protein LOC103189530 [KO:K11429] [EC:2.1.1.362]
103180852  mecom; histone-lysine N-methyltransferase MECOM [KO:K04462] [EC:2.1.1.367]
103184259  prdm16; histone-lysine N-methyltransferase PRDM16 isoform X1 [KO:K22410] [EC:2.1.1.367]
103177255  tmlhe; trimethyllysine dioxygenase, mitochondrial [KO:K00474] [EC:1.14.11.8]
103189441  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
103186924  aldehyde dehydrogenase, dimeric NADP-preferring [KO:K00128] [EC:1.2.1.3]
103184053  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
103180031  aldh9a1a.1; 4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
103174979  bbox1; gamma-butyrobetaine dioxygenase [KO:K00471] [EC:1.14.11.1]
103181397  plod1a; procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 isoform X1 [KO:K00473] [EC:1.14.11.4]
103177516  plod2; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform X1 [KO:K13645] [EC:1.14.11.4]
103180076  colgalt2b; procollagen galactosyltransferase 2 [KO:K11703] [EC:2.4.1.50]
103183070  cercam; procollagen galactosyltransferase 2 [KO:K11703] [EC:2.4.1.50]
103172022  colgalt1b; procollagen galactosyltransferase 1 [KO:K11703] [EC:2.4.1.50]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
cmk00020  Citrate cycle (TCA cycle)
cmk00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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