KEGG   PATHWAY: cpau00630
Entry
cpau00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cupriavidus pauculus
Class
Metabolism; Carbohydrate metabolism
Pathway map
cpau00630  Glyoxylate and dicarboxylate metabolism
cpau00630

Module
cpau_M00012  Glyoxylate cycle [PATH:cpau00630]
cpau_M00621  Glycine cleavage system [PATH:cpau00630]
Other DBs
GO: 0046487 0043648
Organism
Cupriavidus pauculus [GN:cpau]
Gene
EHF44_12880  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
EHF44_25690  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
EHF44_17080  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
EHF44_11415  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
EHF44_12900  malate synthase A [KO:K01638] [EC:2.3.3.9]
EHF44_10925  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
EHF44_10960  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
EHF44_14660  citrate synthase [KO:K01647] [EC:2.3.3.1]
EHF44_19275  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
EHF44_10910  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
EHF44_23505  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
EHF44_15240  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
EHF44_15260  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
EHF44_14785  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
EHF44_19380  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
EHF44_04880  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
EHF44_15255  3-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
EHF44_08430  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
EHF44_13940  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
EHF44_08420  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
EHF44_13945  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
EHF44_08415  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
EHF44_13950  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
EHF44_21030  catalase [KO:K03781] [EC:1.11.1.6]
EHF44_16025  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
EHF44_19990  catalase [KO:K03781] [EC:1.11.1.6]
EHF44_04810  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
EHF44_11135  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
EHF44_11175  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EHF44_07460  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
EHF44_21185  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
EHF44_09535  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EHF44_06050  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
EHF44_06060  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
EHF44_24860  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EHF44_18940  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EHF44_15510  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EHF44_12515  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EHF44_06055  gcvH; glycine cleavage system protein GcvH [KO:K02437]
EHF44_06170  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
EHF44_06165  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
EHF44_13530  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EHF44_06160  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EHF44_08820  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
EHF44_03365  glycerate kinase [KO:K11529] [EC:2.7.1.165]
EHF44_06155  glycerate kinase [KO:K11529] [EC:2.7.1.165]
EHF44_03370  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
EHF44_25455  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EHF44_02615  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
EHF44_21470  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
EHF44_21475  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
EHF44_02625  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
EHF44_21480  fdxH; formate dehydrogenase subunit beta [KO:K00124]
EHF44_02630  formate dehydrogenase beta subunit [KO:K00124]
EHF44_21485  formate dehydrogenase subunit gamma [KO:K00127]
EHF44_02635  formate dehydrogenase subunit gamma [KO:K00127]
EHF44_08815  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
EHF44_09640  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
EHF44_11570  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
EHF44_08785  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
EHF44_27660  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
EHF44_18785  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
EHF44_18780  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
EHF44_18795  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cpau00010  Glycolysis / Gluconeogenesis
cpau00020  Citrate cycle (TCA cycle)
cpau00030  Pentose phosphate pathway
cpau00053  Ascorbate and aldarate metabolism
cpau00071  Fatty acid degradation
cpau00230  Purine metabolism
cpau00250  Alanine, aspartate and glutamate metabolism
cpau00260  Glycine, serine and threonine metabolism
cpau00620  Pyruvate metabolism
cpau00710  Carbon fixation by Calvin cycle
cpau00750  Vitamin B6 metabolism
cpau00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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