KEGG   PATHWAY: cpau00230
Entry
cpau00230                   Pathway                                
Name
Purine metabolism - Cupriavidus pauculus
Class
Metabolism; Nucleotide metabolism
Pathway map
cpau00230  Purine metabolism
cpau00230

Module
cpau_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cpau00230]
cpau_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cpau00230]
cpau_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cpau00230]
cpau_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cpau00230]
cpau_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cpau00230]
cpau_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cpau00230]
cpau_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cpau00230]
Other DBs
GO: 0006163 0042278
Organism
Cupriavidus pauculus [GN:cpau]
Gene
EHF44_17675  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
EHF44_09335  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
EHF44_03930  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
EHF44_11065  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
EHF44_01735  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
EHF44_08645  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
EHF44_14565  formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
EHF44_14875  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
EHF44_08495  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
EHF44_02895  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
EHF44_02900  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
EHF44_02905  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
EHF44_08280  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
EHF44_03255  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
EHF44_03820  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
EHF44_12135  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
EHF44_08545  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
EHF44_15275  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
EHF44_07900  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
EHF44_13275  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
EHF44_12175  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
EHF44_18170  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
EHF44_17905  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
EHF44_17910  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
EHF44_21440  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
EHF44_25985  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
EHF44_22880  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
EHF44_21435  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
EHF44_25990  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
EHF44_22875  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
EHF44_21430  (2Fe-2S)-binding protein [KO:K13483]
EHF44_25995  (2Fe-2S)-binding protein [KO:K13483]
EHF44_22870  aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
EHF44_10220  NUDIX domain-containing protein [KO:K01518] [EC:3.6.1.17]
EHF44_13285  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
EHF44_13365  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
EHF44_17925  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
EHF44_20165  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
EHF44_18140  guanylate kinase [KO:K00942] [EC:2.7.4.8]
EHF44_01555  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
EHF44_07935  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
EHF44_12050  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
EHF44_07940  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
EHF44_06955  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
EHF44_18130  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
EHF44_16630  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
EHF44_11875  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EHF44_15810  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K00951] [EC:2.7.6.5]
EHF44_10420  hypothetical protein [KO:K07816] [EC:2.7.6.5]
EHF44_12245  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
EHF44_08020  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
EHF44_22110  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
EHF44_17920  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
EHF44_02535  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
EHF44_02770  adenylate kinase [KO:K00939] [EC:2.7.4.3]
EHF44_25025  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
EHF44_09215  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
EHF44_08860  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
EHF44_08855  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
EHF44_17945  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
EHF44_17965  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
EHF44_25295  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
EHF44_23410  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
EHF44_17960  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
EHF44_06195  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
EHF44_15150  Zn-dependent hydrolase [KO:K02083] [EC:3.5.3.9]
EHF44_17570  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
EHF44_17575  urease subunit beta [KO:K01429] [EC:3.5.1.5]
EHF44_17585  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
EHF44_25205  ggt; gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cpau00030  Pentose phosphate pathway
cpau00220  Arginine biosynthesis
cpau00250  Alanine, aspartate and glutamate metabolism
cpau00260  Glycine, serine and threonine metabolism
cpau00340  Histidine metabolism
cpau00630  Glyoxylate and dicarboxylate metabolism
cpau00730  Thiamine metabolism
cpau00740  Riboflavin metabolism
cpau00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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