KEGG   PATHWAY: cpic00564
Entry
cpic00564                   Pathway                                
Name
Glycerophospholipid metabolism - Chrysemys picta (western painted turtle)
Class
Metabolism; Lipid metabolism
Pathway map
cpic00564  Glycerophospholipid metabolism
cpic00564

Module
cpic_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:cpic00564]
cpic_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:cpic00564]
cpic_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:cpic00564]
Other DBs
GO: 0006650
Organism
Chrysemys picta (western painted turtle) [GN:cpic]
Gene
101935478  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
101939497  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
101931423  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
101939831  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
101944347  GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
101932383  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X2 [KO:K00629] [EC:2.3.1.15]
101943896  GPAT4; glycerol-3-phosphate acyltransferase 4 isoform X1 [KO:K13506] [EC:2.3.1.15]
101940911  GPAT3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
101943398  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1 [KO:K13509] [EC:2.3.1.51]
101944318  AGPAT1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1 [KO:K13509] [EC:2.3.1.51]
101950477  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X2 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
101945765  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X3 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
101945357  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
101951946  LCLAT1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
101945255  MBOAT2; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
101939129  MBOAT1; lysophospholipid acyltransferase 1 isoform X2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
101948121  GNPAT; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
101938771  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
101948636  PLPP3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
101934148  PLPP1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
101945684  PLPP2; phospholipid phosphatase 2 isoform X1 [KO:K01080] [EC:3.1.3.4]
101949714  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
101948683  LPIN1; phosphatidate phosphatase LPIN1 isoform X2 [KO:K15728] [EC:3.1.3.4]
101940427  LPIN2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
101943768  LPIN3; phosphatidate phosphatase LPIN3 [KO:K15728] [EC:3.1.3.4]
101938427  PLPP5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
101932557  PLPP4; phospholipid phosphatase 4 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
101940928  DGKI; diacylglycerol kinase iota isoform X3 [KO:K00901] [EC:2.7.1.107]
101940221  diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
101933664  DGKA; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
101936224  DGKG; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
101950066  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
101946155  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
101943810  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
101939308  DGKB; diacylglycerol kinase beta isoform X2 [KO:K00901] [EC:2.7.1.107]
101950294  diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
101932990  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
101932654  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
101937224  CHPT1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
101940701  CEPT1; choline/ethanolaminephosphotransferase 1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
101931414  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
101946465  5'-3' exonuclease PLD3-like isoform X2 [KO:K16860] [EC:3.1.4.4]
101947421  PLD3; 5'-3' exonuclease PLD3 isoform X1 [KO:K16860] [EC:3.1.4.4]
101942697  PLD4; 5'-3' exonuclease PLD4 isoform X1 [KO:K16860] [EC:3.1.4.4]
101933197  LCAT; phosphatidylcholine-sterol acyltransferase isoform X1 [KO:K00650] [EC:2.3.1.43]
101948582  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
101945476  PLA2G3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
101950940  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
101932432  basic phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
101932692  basic phospholipase A2 sphenotoxin subunit B-like [KO:K01047] [EC:3.1.1.4]
101942418  PLA2G10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
101932063  PROCA1; protein PROCA1 [KO:K01047] [EC:3.1.1.4]
101946734  PLA2G1B; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
101946229  PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X2 [KO:K01047] [EC:3.1.1.4]
101949272  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
101935895  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
101942789  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
101951104  cytosolic phospholipase A2 beta [KO:K16342] [EC:3.1.1.4]
101935773  PLA2G4F; cytosolic phospholipase A2 zeta isoform X1 [KO:K16342] [EC:3.1.1.4]
101934086  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
101934370  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
101934642  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
101934938  cytosolic phospholipase A2 epsilon isoform X1 [KO:K16342] [EC:3.1.1.4]
101935221  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
101935501  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
101948562  PLA2G4A; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
112060933  LOW QUALITY PROTEIN: cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
101947653  PLB1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
101950913  phospholipase A and acyltransferase 3-like isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
101951554  phospholipase A and acyltransferase 2-like isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
101952358  phospholipase A and acyltransferase 3-like isoform X2 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
101952614  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
101937232  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
101931683  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
101940623  LPCAT2; lysophosphatidylcholine acyltransferase 2 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
101948289  LPCAT1; lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
101940719  LPCAT4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
101944358  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
101953537  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
101936869  PLA2G15; phospholipase A2 group XV [KO:K06129] [EC:3.1.1.5]
101939842  LYPLA2; acyl-protein thioesterase 2 isoform X1 [KO:K06130] [EC:3.1.1.5]
101951780  PNPLA7; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
101934815  LOW QUALITY PROTEIN: patatin-like phospholipase domain-containing protein 6 [KO:K14676] [EC:3.1.1.5]
101936233  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
101946401  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
101936986  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
101954077  ACHE; acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
101937628  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
103307353  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
101944730  cholinesterase-like [KO:K01049] [EC:3.1.1.7]
101935445  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
101945279  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
101948740  LOW QUALITY PROTEIN: acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
101941289  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
101932091  CHKB; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
101951023  CHKA; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
101942754  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
101947714  PCYT1B; choline-phosphate cytidylyltransferase B isoform X2 [KO:K00968] [EC:2.7.7.15]
101941452  PCYT1A; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
101941714  SELENOI; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
101937664  ethanolaminephosphotransferase 1-like [KO:K00993] [EC:2.7.8.1]
101934937  ETNK2; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
101934342  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
101936405  PCYT2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
101939791  ETNPPL; ethanolamine-phosphate phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
101953495  PEMT; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
101934849  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
101951593  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
101933691  PLA1A; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
101949650  PTDSS1; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
101951300  PTDSS2; phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
101949282  PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
101932241  phosphatidylserine decarboxylase proenzyme, mitochondrial-like isoform X2 [KO:K01613] [EC:4.1.1.65]
101952620  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
101950657  CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
101936825  TAFAZZIN; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
101931807  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
101938540  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
101944171  MBOAT7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
cpic00010  Glycolysis / Gluconeogenesis
cpic00260  Glycine, serine and threonine metabolism
cpic00561  Glycerolipid metabolism
cpic00562  Inositol phosphate metabolism
cpic00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
cpic00565  Ether lipid metabolism
cpic00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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