KEGG   PATHWAY: csed00230
Entry
csed00230                   Pathway                                
Name
Purine metabolism - Citrobacter sedlakii
Class
Metabolism; Nucleotide metabolism
Pathway map
csed00230  Purine metabolism
csed00230

Module
csed_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:csed00230]
csed_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:csed00230]
csed_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:csed00230]
csed_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:csed00230]
csed_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:csed00230]
csed_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:csed00230]
Other DBs
GO: 0006163 0042278
Organism
Citrobacter sedlakii [GN:csed]
Gene
JY391_00465  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
JY391_00475  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
JY391_01900  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
JY391_01910  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
JY391_03705  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
JY391_03710  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
JY391_04525  ppnN; nucleotide 5'-monophosphate nucleosidase [KO:K06966] [EC:3.2.2.10 3.2.2.-]
JY391_04585  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
JY391_04590  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
JY391_04655  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
JY391_04660  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
JY391_04665  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
JY391_04695  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
JY391_05130  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
JY391_05135  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
JY391_05675  pgeF; polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
JY391_06265  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
JY391_06445  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
JY391_06505  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
JY391_06510  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
JY391_06525  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
JY391_06535  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
JY391_06540  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
JY391_06655  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
JY391_06895  [KO:K01951] [EC:6.3.5.2]
JY391_06965  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
JY391_07270  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
JY391_07405  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
JY391_07615  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
JY391_07620  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
JY391_08935  [KO:K01241] [EC:3.2.2.4]
JY391_09980  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
JY391_11680  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
JY391_12710  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
JY391_13175  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
JY391_14945  pgm; alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
JY391_15030  nagD; ribonucleotide monophosphatase NagD [KO:K02566] [EC:3.1.3.5]
JY391_16145  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
JY391_16150  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
JY391_16230  [KO:K11751] [EC:3.1.3.5 3.6.1.45]
JY391_16245  gsk; inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
JY391_16260  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
JY391_16285  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
JY391_16740  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
JY391_17095  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
JY391_17100  [KO:K11178] [EC:1.17.1.4]
JY391_17105  [KO:K11177] [EC:1.17.1.4]
JY391_17215  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
JY391_17525  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
JY391_17680  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
JY391_17815  [KO:K00364] [EC:1.7.1.7]
JY391_18080  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH [KO:K01525] [EC:3.6.1.41]
JY391_18365  yjjX; inosine/xanthosine triphosphatase [KO:K01529]
JY391_18425  [KO:K00926] [EC:2.7.2.2]
JY391_18550  hiuH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
JY391_18615  [KO:K01519] [EC:3.6.1.66]
JY391_18975  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
JY391_18985  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
JY391_19100  [KO:K01430] [EC:3.5.1.5]
JY391_19105  [KO:K01429] [EC:3.5.1.5]
JY391_19110  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
JY391_19460  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
JY391_19530  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
JY391_19705  [KO:K01119] [EC:3.1.4.16 3.1.3.6]
JY391_19900  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
JY391_21030  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
JY391_21035  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
JY391_22025  cyaA; class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
JY391_22155  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
csed00030  Pentose phosphate pathway
csed00220  Arginine biosynthesis
csed00250  Alanine, aspartate and glutamate metabolism
csed00260  Glycine, serine and threonine metabolism
csed00340  Histidine metabolism
csed00630  Glyoxylate and dicarboxylate metabolism
csed00730  Thiamine metabolism
csed00740  Riboflavin metabolism
csed00790  Folate biosynthesis
KO pathway
ko00230   

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