KEGG   PATHWAY: csk00230
Entry
csk00230                    Pathway                                
Name
Purine metabolism - Cronobacter sakazakii ES15
Class
Metabolism; Nucleotide metabolism
Pathway map
csk00230  Purine metabolism
csk00230

Module
csk_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:csk00230]
csk_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:csk00230]
csk_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:csk00230]
csk_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:csk00230]
csk_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:csk00230]
csk_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:csk00230]
Other DBs
GO: 0006163 0042278
Organism
Cronobacter sakazakii ES15 [GN:csk]
Gene
ES15_0056  spoT; bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ES15_0058  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
ES15_0105  uraH; putative hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ES15_0114  yagT; putative xanthine dehydrogenase YagT iron-sulfur-binding subunit [KO:K13483]
ES15_0115  yagS; putative xanthine dehydrogenase YagS FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
ES15_0116  yagR; putative xanthine dehydrogenase YagR molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
ES15_0270  [KO:K20881] [EC:3.1.3.-]
ES15_0272  nudE; ADP-ribose diphosphatase NudE [KO:K08312] [EC:3.6.1.-]
ES15_0309  prsA1; putative ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ES15_0489  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
ES15_0520  cpdB; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ES15_0555  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ES15_0647  nudF; ADP-ribose pyrophosphatase NudF [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ES15_0649  [KO:K03651] [EC:3.1.4.53]
ES15_0660  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
ES15_0770  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ES15_0779  relA; GDP/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
ES15_0780  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
ES15_0796  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
ES15_0797  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
ES15_0798  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
ES15_0806  surE; 5'(3')-nucleotidase/polyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ES15_0842  nrdB1; ribonucleotide-diphosphate reductase subunit beta 1 [KO:K00526] [EC:1.17.4.1]
ES15_0843  nrdA1; ribonucleotide-diphosphate reductase subunit alpha 1 [KO:K00525] [EC:1.17.4.1]
ES15_0941  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ES15_0977  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ES15_1010  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ES15_1022  guaB; inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ES15_1023  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
ES15_1030  ppx1; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ES15_1032  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ES15_1033  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
ES15_1044  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ES15_1160  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ES15_1183  yfbR; 5'-nucleotidase YfbR [KO:K08722] [EC:3.1.3.89]
ES15_1218  nrdB2; ribonucleotide-diphosphate reductase subunit beta 2 [KO:K00526] [EC:1.17.4.1]
ES15_1219  nrdA2; ribonucleotide-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
ES15_1454  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
ES15_1605  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
ES15_1725  prsA2; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ES15_2132  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ES15_2358  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ES15_2730  [KO:K01835] [EC:5.4.2.2]
ES15_2745  [KO:K02566] [EC:3.1.3.5]
ES15_2854  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
ES15_2855  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
ES15_2874  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ES15_2877  gsk; inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
ES15_2882  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
ES15_2892  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ES15_2992  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ES15_3108  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
ES15_3168  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
ES15_3194  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ES15_3219  guaC; guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
ES15_3271  [KO:K01525] [EC:3.6.1.41]
ES15_3323  [KO:K01529]
ES15_3343  [KO:K03784] [EC:2.4.2.1]
ES15_3344  [KO:K01839] [EC:5.4.2.7]
ES15_3435  [KO:K00926] [EC:2.7.2.2]
ES15_3610  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ES15_3611  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ES15_3683  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ES15_3703  ppx2; guanosine pentaphosphate phosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
csk00030  Pentose phosphate pathway
csk00220  Arginine biosynthesis
csk00250  Alanine, aspartate and glutamate metabolism
csk00260  Glycine, serine and threonine metabolism
csk00340  Histidine metabolism
csk00630  Glyoxylate and dicarboxylate metabolism
csk00730  Thiamine metabolism
csk00740  Riboflavin metabolism
csk00790  Folate biosynthesis
KO pathway
ko00230   

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