KEGG   PATHWAY: csx00230
Entry
csx00230                    Pathway                                
Name
Purine metabolism - Corynebacterium singulare
Class
Metabolism; Nucleotide metabolism
Pathway map
csx00230  Purine metabolism
csx00230

Module
csx_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:csx00230]
csx_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:csx00230]
csx_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:csx00230]
csx_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:csx00230]
csx_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:csx00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium singulare [GN:csx]
Gene
CSING_00310  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
CSING_01370  cya; family 3 adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CSING_01675  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CSING_02430  adk; adenylate kinase-like kinase [KO:K00939] [EC:2.7.4.3]
CSING_02700  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CSING_02705  [KO:K00088] [EC:1.1.1.205]
CSING_02715  guaA; GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
CSING_02970  [KO:K01488] [EC:3.5.4.4]
CSING_03145  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CSING_03150  purE; phosphoribosylaminoimidazole carboxylase, PurE protein [KO:K01588] [EC:5.4.99.18]
CSING_04540  purN; formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CSING_04545  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CSING_04905  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CSING_04985  ppx2; Ppx/GppA phosphatase family [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CSING_06555  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CSING_06760  iunH1; Inosine-uridine nucleoside N-ribohydrolase [KO:K01239] [EC:3.2.2.1]
CSING_07710  [KO:K01081] [EC:3.1.3.5]
CSING_07715  relA; (p)ppGpp synthetase, RelA/SpoT family [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CSING_07720  apt; PRPP-binding protein, adenine/guanine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CSING_07805  [KO:K19710] [EC:2.7.7.53]
CSING_09055  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CSING_09640  nagD; putative sugar phosphatase of HAD superfamily [KO:K02566] [EC:3.1.3.5]
CSING_09955  [KO:K01129] [EC:3.1.5.1]
CSING_10390  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CSING_10475  nrdE1; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
CSING_10480  nrdF1; ribonucleoside-diphosphate reductase, class 1b, beta subunit [KO:K00526] [EC:1.17.4.1]
CSING_10830  [KO:K01519] [EC:3.6.1.66]
CSING_10900  nrdF2; ribonucleoside-diphosphate reductase class Ib beta subunit [KO:K00526] [EC:1.17.4.1]
CSING_10910  nrdE2; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
CSING_10975  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
CSING_11180  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CSING_11185  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CSING_11255  purL; phosphoribosylformylglycinamidine synthase II [KO:K23269]
CSING_11260  purQ; phosphoribosylformylglycinamidine synthase subunit I [KO:K23265]
CSING_11265  [KO:K23264]
CSING_11290  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CSING_11315  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CSING_11320  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CSING_11645  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CSING_11895  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
CSING_11910  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CSING_12070  cysNC; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
CSING_12075  mmcV; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
CSING_12415  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
CSING_12420  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
CSING_12425  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
csx00030  Pentose phosphate pathway
csx00220  Arginine biosynthesis
csx00250  Alanine, aspartate and glutamate metabolism
csx00260  Glycine, serine and threonine metabolism
csx00340  Histidine metabolism
csx00630  Glyoxylate and dicarboxylate metabolism
csx00730  Thiamine metabolism
csx00740  Riboflavin metabolism
csx00790  Folate biosynthesis
KO pathway
ko00230   

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