KEGG   PATHWAY: csyr04612
Entry
csyr04612                   Pathway                                
Name
Antigen processing and presentation - Carlito syrichta (Philippine tarsier)
Class
Organismal Systems; Immune system
Pathway map
csyr04612  Antigen processing and presentation
csyr04612

Other DBs
GO: 0019885 0019886 0042591
Organism
Carlito syrichta (Philippine tarsier) [GN:csyr]
Gene
103249397  CALR; calreticulin [KO:K08057]
103249578  [KO:K06541]
103250182  TAPBPL; LOW QUALITY PROTEIN: tapasin-related protein [KO:K28445]
103250675  CANX; calnexin isoform X1 [KO:K08054]
103251273  [KO:K07980]
103251385  CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
103251393  [KO:K06751]
103252157  CD4; T-cell surface glycoprotein CD4 [KO:K06454]
103252293  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
103253249  [KO:K06541]
103253266  [KO:K06541]
103253268  [KO:K06541]
103253410  [KO:K06541]
103254128  [KO:K24233]
103254332  HSPA4; heat shock 70 kDa protein 4 isoform X1 [KO:K09489]
103254879  B2M; beta-2-microglobulin [KO:K08055]
103256412  HSPA6; heat shock 70 kDa protein 6 [KO:K03283]
103256658  [KO:K06516]
103256945  [KO:K06752]
103257049  [KO:K06541]
103258643  [KO:K03283]
103258654  [KO:K03283]
103258929  CD8B; T-cell surface glycoprotein CD8 beta chain [KO:K06459]
103260333  [KO:K03283]
103260588  [KO:K07980]
103260944  [KO:K01365] [EC:3.4.22.15]
103260950  [KO:K01365] [EC:3.4.22.15]
103261194  HSPA2; heat shock-related 70 kDa protein 2 isoform X1 [KO:K26598]
103261838  KIR2DL4; LOW QUALITY PROTEIN: killer cell immunoglobulin-like receptor 2DL4 [KO:K24232]
103262024  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
103262563  TAPBP; tapasin [KO:K08058]
103262579  HSPA5; 78 kDa glucose-regulated protein [KO:K09490] [EC:3.6.4.10]
103262681  [KO:K06752]
103262695  [KO:K06752]
103262757  [KO:K06752]
103263270  [KO:K06541]
103264163  CIITA; MHC class II transactivator [KO:K08060] [EC:2.7.11.1]
103264451  NFYA; nuclear transcription factor Y subunit alpha [KO:K08064]
103264939  [KO:K24233]
103264940  [KO:K06541]
103266111  CD74; HLA class II histocompatibility antigen gamma chain [KO:K06505]
103266451  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
103266489  NFYB; nuclear transcription factor Y subunit beta isoform X2 [KO:K08065]
103266905  [KO:K06752]
103267365  [KO:K06752]
103267926  NFYC; nuclear transcription factor Y subunit gamma isoform X1 [KO:K08066]
103267988  [KO:K06752]
103268467  [KO:K06751]
103269019  IFNG; interferon gamma [KO:K04687]
103269400  [KO:K08057]
103270149  TNF; tumor necrosis factor [KO:K03156]
103270208  [KO:K10785]
103270219  [KO:K10785]
103270698  PSME3; proteasome activator complex subunit 3 isoform X1 [KO:K06698]
103270816  [KO:K24233]
103270906  [KO:K06541]
103270978  [KO:K06541]
103270979  [KO:K06541]
103270984  [KO:K06541]
103270985  [KO:K06541]
103271234  HSP90AB1; heat shock protein HSP 90-beta isoform X2 [KO:K04079]
103271292  [KO:K03283]
103271436  [KO:K06751]
103271929  [KO:K06752]
103271932  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
103271934  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
103271936  [KO:K06752]
103272251  PSME2; proteasome activator complex subunit 2 isoform X1 [KO:K06697]
103272252  PSME1; proteasome activator complex subunit 1 isoform X1 [KO:K06696]
103272282  [KO:K06752]
103272395  [KO:K06541]
103273534  [KO:K06751]
103273536  [KO:K06751]
103274243  [KO:K01365] [EC:3.4.22.15]
103274244  [KO:K01365] [EC:3.4.22.15]
103274246  [KO:K01365] [EC:3.4.22.15]
103274261  [KO:K01365] [EC:3.4.22.15]
103274337  RFX5; DNA-binding protein RFX5 isoform X1 [KO:K08061]
103275039  CTSB; cathepsin B [KO:K01363] [EC:3.4.22.1]
103275558  LGMN; legumain [KO:K01369] [EC:3.4.22.34]
103275796  [KO:K03283]
103276261  [KO:K06516]
103276262  [KO:K06516]
103276452  [KO:K24234]
103276998  [KO:K06751]
103277080  [KO:K06751]
103277262  RFXANK; DNA-binding protein RFXANK isoform X1 [KO:K08062]
110594418  [KO:K06541]
110594908  [KO:K24233]
Reference
PMID:15771591
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
DOI:10.1146/annurev.immunol.22.012703.104538
Reference
PMID:15814328
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
DOI:10.1532/IJH97.04200
Reference
PMID:11905820
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
DOI:10.1038/35100512
Reference
PMID:15304636
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
DOI:10.1152/physiol.00002.2004
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:12776207
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
DOI:10.1038/nri1110
Reference
PMID:12974477
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
DOI:10.1038/nri1149
Reference
PMID:15224093
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
DOI:10.1038/ni1082
Reference
PMID:16181333
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
DOI:10.1111/j.0105-2896.2005.00316.x
Reference
PMID:15653312
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
DOI:10.1016/j.coi.2004.11.008
Reference
PMID:11244040
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
DOI:10.1146/annurev.immunol.19.1.331
Reference
PMID:15745856
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
DOI:10.1016/j.it.2005.01.005
Reference
PMID:15224094
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
DOI:10.1038/ni1088
Reference
PMID:15653315
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
DOI:10.1016/j.coi.2004.12.004
Reference
PMID:20010787
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
DOI:10.1038/nri2687
Related
pathway
csyr03050  Proteasome
csyr04650  Natural killer cell mediated cytotoxicity
csyr04660  T cell receptor signaling pathway
KO pathway
ko04612   

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