KEGG   PATHWAY: daq00230
Entry
daq00230                    Pathway                                
Name
Purine metabolism - Dickeya aquatica
Class
Metabolism; Nucleotide metabolism
Pathway map
daq00230  Purine metabolism
daq00230

Module
daq_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:daq00230]
daq_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:daq00230]
daq_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:daq00230]
daq_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:daq00230]
daq_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:daq00230]
Other DBs
GO: 0006163 0042278
Organism
Dickeya aquatica [GN:daq]
Gene
DAQ1742_00419  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
DAQ1742_04135  nudE; ADP-ribose diphosphatase.ADP-ribose hydrolases in general act as protective agents against excessive intracellular accumulation of ADP-ribose, as high intracellular levels of ADP-ribose can be damaging to the cell [KO:K08312] [EC:3.6.1.-]
DAQ1742_00718  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
DAQ1742_03005  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
DAQ1742_02138  prsA; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
DAQ1742_01331  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DAQ1742_00313  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
DAQ1742_03080  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DAQ1742_02292  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
DAQ1742_01067  purL; Phosphoribosylformylglycinamidine synthase, synthetase subunit / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit [KO:K01952] [EC:6.3.5.3]
DAQ1742_03079  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
DAQ1742_01162  purK; Phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
DAQ1742_01163  purE; Phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
DAQ1742_03068  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DAQ1742_04227  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DAQ1742_02490  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DAQ1742_00314  purH; IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DAQ1742_03134  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DAQ1742_03125  ushA; UDP-sugar hydrolase; 5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
DAQ1742_04137  yrfG; FIG001957: putative hydrolase [KO:K20881] [EC:3.1.3.-]
DAQ1742_00719  deoD; Purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
DAQ1742_03263  yaiE; Cytoplasmic protein YaiE [KO:K09913] [EC:2.4.2.1 2.4.2.2]
DAQ1742_00976  yfiH; COG1496: Uncharacterized conserved protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
DAQ1742_01000  hpt; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DAQ1742_01116  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
DAQ1742_01104  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DAQ1742_03906  yjjX; Inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
DAQ1742_03625  rdgB; Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) [KO:K01519] [EC:3.6.1.66]
DAQ1742_03456  gpt; Xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
DAQ1742_01117  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
DAQ1742_01385  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
DAQ1742_02577  guaD; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
DAQ1742_00042  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
DAQ1742_03114  nrdA; Ribonucleotide reductase of class Ia (aerobic), alpha subunit [KO:K00525] [EC:1.17.4.1]
DAQ1742_03115  nrdB; Ribonucleotide reductase of class Ia (aerobic), beta subunit [KO:K00526] [EC:1.17.4.1]
DAQ1742_00463  nrdD; Ribonucleotide reductase of class III (anaerobic), large subunit [KO:K21636] [EC:1.1.98.6]
DAQ1742_01022  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
DAQ1742_01349  yfbR; Nucleotidase YfbR, HD superfamily [KO:K08722] [EC:3.1.3.89]
DAQ1742_00040  spoT; GTP pyrophosphokinase, (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DAQ1742_04250  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DAQ1742_01153  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DAQ1742_03551  relA; GTP pyrophosphokinase, (p)ppGpp synthetase I [KO:K00951] [EC:2.7.6.5]
DAQ1742_04205  cyaA; Adenylate cyclase [KO:K05851] [EC:4.6.1.1]
DAQ1742_01655  cyaB; Adenylate cyclase [KO:K05873] [EC:4.6.1.1]
DAQ1742_03939  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
DAQ1742_02193  add; Adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DAQ1742_02917  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
DAQ1742_03335  yqdH; Decarboxylase family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
DAQ1742_03595  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
DAQ1742_03129  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
DAQ1742_03550  mazG; Nucleoside triphosphate pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
DAQ1742_00421  cpdA; 3',5'-cyclic-nucleotide phosphodiesterase [KO:K03651] [EC:3.1.4.53]
DAQ1742_03862  apaH; Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
DAQ1742_03532  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
DAQ1742_03533  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
DAQ1742_00577  Uricase [KO:K16840] [EC:4.1.1.97]
DAQ1742_03485  hyuE; Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
DAQ1742_03484  cda; Putative chitin deacetylase [KO:K16842] [EC:3.5.2.5]
DAQ1742_03471  allC; N-carbamoyl-L-amino acid hydrolase [KO:K02083] [EC:3.5.3.9]
DAQ1742_03472  pucG; Serine--pyruvate aminotransferase / L-alanine:glyoxylate aminotransferase [KO:K00839] [EC:2.6.1.112]
DAQ1742_03480  atzE; Biuret hydrolase [KO:K22601] [EC:2.1.3.5]
DAQ1742_03478  Gamma-glutamyltranspeptidase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
daq00030  Pentose phosphate pathway
daq00220  Arginine biosynthesis
daq00250  Alanine, aspartate and glutamate metabolism
daq00260  Glycine, serine and threonine metabolism
daq00340  Histidine metabolism
daq00630  Glyoxylate and dicarboxylate metabolism
daq00730  Thiamine metabolism
daq00740  Riboflavin metabolism
daq00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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