KEGG   PATHWAY: dra00230
Entry
dra00230                    Pathway                                
Name
Purine metabolism - Deinococcus radiodurans
Class
Metabolism; Nucleotide metabolism
Pathway map
dra00230  Purine metabolism
dra00230

Module
dra_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:dra00230]
dra_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:dra00230]
dra_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:dra00230]
dra_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:dra00230]
dra_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:dra00230]
dra_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:dra00230]
dra_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:dra00230]
Other DBs
GO: 0006163 0042278
Organism
Deinococcus radiodurans [GN:dra]
Gene
DR_1007  MutT/nudix family protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
DR_2204  MutT/nudix family protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
DR_2135  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
DR_0303  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
DR_1456  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
DR_0220  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DR_1431  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
DR_2026  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DR_0222  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
DR_0224  hypothetical protein [KO:K23264] [EC:6.3.5.3]
DR_0223  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
DR_1394  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
DR_0024  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
DR_0023  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
DR_0226  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DR_2178  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DR_0868  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DR_0878  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DR_0505  5`-nucleotidase family protein [KO:K01081] [EC:3.1.3.5]
DR_A0018  5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
DR_2397  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
DR_2166  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
DR_1966  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
DR_1376  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DR_1878  inosine-5`-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
DR_2499  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DR_0179  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
DR_1617  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
DR_A0177  xanthine dehydrogenase, N-terminal subunit [KO:K13481] [EC:1.17.1.4]
DR_A0178  xanthine dehydrogenase, C-terminal subunit [KO:K13482] [EC:1.17.1.4]
DR_A0237  oxidoreductase [KO:K11177] [EC:1.17.1.4]
DR_A0231  oxidoreductase [KO:K11177] [EC:1.17.1.4]
DR_A0232  oxidoreductase [KO:K11178] [EC:1.17.1.4]
DR_A0236  oxidoreductase [KO:K11178] [EC:1.17.1.4]
DR_A0235  oxidoreductase iron-sulfur subunit [KO:K13483]
DR_A0233  oxidoreductase iron-sulfur subunit [KO:K13483]
DR_1874  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
DR_A0180  guanine deaminase [KO:K01487] [EC:3.5.4.3]
DR_2289  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
DR_B0108  ribonucleoside-diphosphate reductase, alpha chain [KO:K00525] [EC:1.17.4.1]
DR_2374  ribonucleoside-diphosphate reductase-like protein [KO:K00525] [EC:1.17.4.1]
DR_B0109  nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
DR_1808  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
DR_1006  dGTP triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
DR_1838  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DR_A0185  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DR_0035  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
DR_A0270  adenine deaminase [KO:K01486] [EC:3.5.4.2]
DR_1736  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
DR_1281  hypothetical protein [KO:K24670] [EC:3.1.4.16 3.1.3.60]
DR_2117  adenylate kinase [KO:K00939] [EC:2.7.4.3]
DR_A0014  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
DR_A0016  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
DR_1160  uricase [KO:K00365] [EC:1.7.3.3]
DR_1161  hypothetical protein [KO:K07127] [EC:3.5.2.17]
DR_1158  hypothetical protein [KO:K13485] [EC:4.1.1.97]
DR_1153  allantoinase [KO:K01466] [EC:3.5.2.5]
DR_1154  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
DR_1152  hypothetical protein [KO:K14977] [EC:3.5.3.26]
DR_A0318  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
DR_A0319  bifunctional urease subunit gamma/beta [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
dra00030  Pentose phosphate pathway
dra00220  Arginine biosynthesis
dra00250  Alanine, aspartate and glutamate metabolism
dra00260  Glycine, serine and threonine metabolism
dra00340  Histidine metabolism
dra00630  Glyoxylate and dicarboxylate metabolism
dra00730  Thiamine metabolism
dra00740  Riboflavin metabolism
dra00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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