KEGG   PATHWAY: ebe00630
Entry
ebe00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli BL21(DE3)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ebe00630  Glyoxylate and dicarboxylate metabolism
ebe00630

Module
ebe_M00012  Glyoxylate cycle [PATH:ebe00630]
ebe_M00621  Glycine cleavage system [PATH:ebe00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli BL21(DE3) [GN:ebe]
Gene
B21_03847  aceA; isocitrate lyase monomer, subunit of isocitrate lyase [KO:K01637] [EC:4.1.3.1]
B21_03901  acs; acetyl-CoA synthetase (AMP-forming) [KO:K01895] [EC:6.2.1.1]
B21_02794  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
B21_03846  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
B21_03047  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
B21_00669  gltA; citrate synthase monomer, subunit of citrate synthase [KO:K01647] [EC:2.3.3.1]
B21_01264  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
B21_00116  acnB; bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
B21_02655  yqeF; predicted acyltransferase [KO:K00626] [EC:2.3.1.9]
B21_02110  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
B21_02711  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
B21_02798  glcD; glycolate oxidase, predicted FAD-linked subunit, subunit of glycolate oxidase [KO:K00104] [EC:1.1.99.14]
B21_02797  glcE; glycolate oxidase, predicted FAD-binding subunit, subunit of glycolate oxidase [KO:K11472] [EC:1.1.99.14]
B21_02796  glcF; glycolate oxidase, predicted iron-sulfur subunit, subunit of glycolate oxidase [KO:K11473] [EC:1.1.99.14]
B21_01689  katE; hydroperoxidase / heme d synthase [KO:K03781] [EC:1.11.1.6]
B21_01037  ghrA; glyoxylate reductase / hydroxypyruvate reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
B21_03354  ghrB; 2-ketoaldonate reductase / glyoxylate reductase B / glyoxylate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
B21_03189  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
B21_03704  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
B21_02407  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
B21_02698  gcvP; glycine decarboxylase, subunit of glycine cleavage system [KO:K00281] [EC:1.4.4.2]
B21_02700  gcvT; aminomethyltransferase, subunit of glycine cleavage system [KO:K00605] [EC:2.1.2.10]
B21_00114  lpd; E3 monomer, subunit of lipoamide dehydrogenase, pyruvate dehydrogenase multienzyme complex, glycine cleavage system and 2-oxoglutarate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
B21_02699  gcvH; glycine cleavage system H protein [KO:K02437]
B21_00462  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
B21_00463  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
B21_00464  glxR; tartronate semialdehyde reductase 2 [KO:K00042] [EC:1.1.1.60]
B21_02941  garR; GarR [KO:K00042] [EC:1.1.1.60]
B21_00469  glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
B21_02940  garK; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
B21_01382  aldA; aldehyde dehydrogenase A, NAD-linked [KO:K07248] [EC:1.2.1.22 1.2.1.21]
B21_02606  fucO; L-1,2-propanediol oxidoreductase monomer, subunit of L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
B21_02881  ttdA; L-tartrate dehydratase, alpha subunit, subunit of alpha subunit complex and L-tartrate dehydratase [KO:K03779] [EC:4.2.1.32]
B21_02882  ttdB; L-tartrate dehydratase, beta subunit, subunit of beta subunit complex and L-tartrate dehydratase [KO:K03780] [EC:4.2.1.32]
B21_01758  yeaU; D-malate dehydrogenase (decarboxylating) [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
B21_01809  eda; multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
B21_03728  fdoG; formate dehydrogenase-O, alpha subunit, subunit of formate dehydrogenase-O [KO:K00123] [EC:1.17.1.9]
B21_03727  fdoH; formate dehydrogenase-O, beta subunit, subunit of formate dehydrogenase-O [KO:K00124]
B21_03726  fdoI; formate dehydrogenase-O, gamma subunit, subunit of formate dehydrogenase-O [KO:K00127]
B21_01218  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
B21_02244  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
B21_02245  frc; formyl-CoA transferase monomer, subunit of formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ebe00010  Glycolysis / Gluconeogenesis
ebe00020  Citrate cycle (TCA cycle)
ebe00030  Pentose phosphate pathway
ebe00053  Ascorbate and aldarate metabolism
ebe00071  Fatty acid degradation
ebe00230  Purine metabolism
ebe00250  Alanine, aspartate and glutamate metabolism
ebe00260  Glycine, serine and threonine metabolism
ebe00620  Pyruvate metabolism
ebe00710  Carbon fixation by Calvin cycle
ebe00750  Vitamin B6 metabolism
ebe00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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